Baker Bros. Advisors Lp

EDGAR CIK 0001263508

KALA BIO, Inc. - KALA

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Other owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$2.00 M
310,559 Shares
Indirect Sells
2
($1.06) M
-730,408 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
10/01/2025
10/02/2025
Sell
-513,607 @ $1.38
 ($710,729) 425,006 (-54.72%) Indirect - See Footnotes
09/30/2025
10/02/2025
Sell
-216,801 @ $1.60
 ($345,993) 887,973 (-19.62%) Indirect - See Footnotes
12/30/2024
12/31/2024
Buy
310,559 @ $6.44
 $2,000,000 1,083,398 (40.18%) Indirect - See Footnotes

Celcuity Inc. - CELC

  1. Services
  2. Health Services
  3. Medical Laboratories
10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$9.57 M
170,100 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
09/08/2025
09/10/2025
Buy
170,100 @ $56.27
 $9,571,319 7,211,484 (2.42%) Indirect - See Footnotes

Madrigal Pharmaceuticals, Inc. - MDGL

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
3
$61.92 M
165,683 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
08/20/2025
08/20/2025
Buy
59,901 @ $385.16
 $23,071,366 1,947,968 (3.17%) Indirect - See Footnotes
08/18/2025
08/20/2025
Buy
68,618 @ $364.04
 $24,979,827 1,859,091 (3.83%) Indirect - See Footnotes
08/18/2025
08/20/2025
Buy
37,164 @ $373.21
 $13,869,831 1,893,120 (2.00%) Indirect - See Footnotes

Kymera Therapeutics, Inc. - KYMR

  1. Manufacturing
  2. Chemicals
  3. Biological Products, (no Disgnostic Substances)
Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$28.84 M
655,500 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
06/30/2025
06/30/2025
Buy
655,500 @ $44.00
 $28,842,000 6,117,295 (12.00%) Indirect - See Footnotes

Immunocore Holdings plc - IMCR

  1. Manufacturing
  2. Chemicals
  3. Biological Products, (no Disgnostic Substances)
Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$23.99 M
807,338 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
03/17/2025
03/19/2025
Buy
807,338 @ $29.72
 $23,993,224 2,144,060 (60.40%) Indirect - See Footnotes

BeOne Medicines Ltd. - ONC

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
0
$0
0 Shares
Indirect Sells
2
($384.74) M
-1,769,844 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
02/28/2025
02/28/2025
Sell
-732,827 @ $260.00
 ($190,535,020) 8,068,411 (-8.33%) Indirect - See Footnotes
12/09/2024
12/10/2024
Sell
-1,037,017 @ $187.27
 ($194,200,043) 8,740,387 (-10.61%) Indirect - See Footnotes

Bicycle Therapeutics Plc - BCYC

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director 10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
2
$21.23 M
1,485,397 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
12/16/2024
12/17/2024
Buy
500,000 @ $15.34
 $7,670,900 9,995,274 (5.27%) Indirect - See Footnotes
12/13/2024
12/17/2024
Buy
985,397 @ $13.76
 $13,559,485 9,537,643 (11.52%) Indirect - See Footnotes