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Baker Bros. Advisors Lp
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Include option trades
EDGAR CIK
0001263508
Entrada Therapeutics, Inc. - TRDA
Manufacturing
Chemicals
Pharmaceutical Preparations
10% owner
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
4
$1.61 M
206,911
Shares
Indirect Sells
0
$0
0
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
11/20/2025
11/24/2025
Buy
28,867 @ $9.07
$261,846
4,691,392
(0.62%)
Indirect - See Footnotes
11/12/2025
11/12/2025
Buy
100,736 @ $7.76
$781,638
4,664,924
(2.21%)
Indirect - See Footnotes
11/11/2025
11/12/2025
Buy
46,434 @ $7.50
$348,193
4,572,549
(1.03%)
Indirect - See Footnotes
11/10/2025
11/12/2025
Buy
30,874 @ $7.21
$222,756
4,529,969
(0.69%)
Indirect - See Footnotes
KALA BIO, Inc. - KALA
Manufacturing
Chemicals
Pharmaceutical Preparations
Other owner
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
1
$2.00 M
310,559
Shares
Indirect Sells
2
($1.06) M
-730,408
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
10/01/2025
10/02/2025
Sell
-513,607 @ $1.38
($710,729)
425,006
(-54.72%)
Indirect - See Footnotes
09/30/2025
10/02/2025
Sell
-216,801 @ $1.60
($345,993)
887,973
(-19.62%)
Indirect - See Footnotes
12/30/2024
12/31/2024
Buy
310,559 @ $6.44
$2,000,000
1,083,398
(40.18%)
Indirect - See Footnotes
Celcuity Inc. - CELC
Services
Health Services
Medical Laboratories
10% owner
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
1
$9.57 M
170,100
Shares
Indirect Sells
0
$0
0
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
09/08/2025
09/10/2025
Buy
170,100 @ $56.27
$9,571,319
7,211,484
(2.42%)
Indirect - See Footnotes
Madrigal Pharmaceuticals, Inc. - MDGL
Manufacturing
Chemicals
Pharmaceutical Preparations
Director
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
3
$61.92 M
165,683
Shares
Indirect Sells
0
$0
0
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
08/20/2025
08/20/2025
Buy
59,901 @ $385.16
$23,071,366
1,947,968
(3.17%)
Indirect - See Footnotes
08/18/2025
08/20/2025
Buy
68,618 @ $364.04
$24,979,827
1,859,091
(3.83%)
Indirect - See Footnotes
08/18/2025
08/20/2025
Buy
37,164 @ $373.21
$13,869,831
1,893,120
(2.00%)
Indirect - See Footnotes
Kymera Therapeutics, Inc. - KYMR
Manufacturing
Chemicals
Biological Products, (no Disgnostic Substances)
Director
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
1
$28.84 M
655,500
Shares
Indirect Sells
0
$0
0
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
06/30/2025
06/30/2025
Buy
655,500 @ $44.00
$28,842,000
6,117,295
(12.00%)
Indirect - See Footnotes
Immunocore Holdings plc - IMCR
Manufacturing
Chemicals
Biological Products, (no Disgnostic Substances)
Director
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
1
$23.99 M
807,338
Shares
Indirect Sells
0
$0
0
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
03/17/2025
03/19/2025
Buy
807,338 @ $29.72
$23,993,224
2,144,060
(60.40%)
Indirect - See Footnotes
BeOne Medicines Ltd. - ONC
Manufacturing
Chemicals
Pharmaceutical Preparations
Director
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
0
$0
0
Shares
Indirect Sells
1
($190.54) M
-732,827
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
02/28/2025
02/28/2025
Sell
-732,827 @ $260.00
($190,535,020)
8,068,411
(-8.33%)
Indirect - See Footnotes
Bicycle Therapeutics Plc - BCYC
Manufacturing
Chemicals
Pharmaceutical Preparations
Director
10% owner
Direct Buys
0
$0
0
Shares
Direct Sells
0
$0
0
Shares
Indirect Buys
2
$21.23 M
1,485,397
Shares
Indirect Sells
0
$0
0
Shares
Monthly Values
Show Transactions
Transaction
Filed
Type
Shares @ Price
Value
Balance ( Change % )
Ownership
12/16/2024
12/17/2024
Buy
500,000 @ $15.34
$7,670,900
9,995,274
(5.27%)
Indirect - See Footnotes
12/13/2024
12/17/2024
Buy
985,397 @ $13.76
$13,559,485
9,537,643
(11.52%)
Indirect - See Footnotes