Baker Bros. Advisors Lp

EDGAR CIK 0001263508

Madrigal Pharmaceuticals, Inc. - MDGL

Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
3
$61.92 M
165,683 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
08/20/2025
08/20/2025
Buy
59,901 @ $385.16
$23,071,366 1,947,968 (3.17%) Indirect - See Footnotes
08/18/2025
08/20/2025
Buy
68,618 @ $364.04
$24,979,827 1,859,091 (3.83%) Indirect - See Footnotes
08/18/2025
08/20/2025
Buy
37,164 @ $373.21
$13,869,831 1,893,120 (2.00%) Indirect - See Footnotes

Kymera Therapeutics, Inc. - KYMR

Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$28.84 M
655,500 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
06/30/2025
06/30/2025
Buy
655,500 @ $44.00
$28,842,000 6,117,295 (12.00%) Indirect - See Footnotes

Immunocore Holdings plc - IMCR

Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$23.99 M
807,338 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
03/17/2025
03/19/2025
Buy
807,338 @ $29.72
$23,993,224 2,144,060 (60.40%) Indirect - See Footnotes

BeOne Medicines Ltd. - ONC

Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
0
$0
0 Shares
Indirect Sells
2
($384.74) M
-1,769,844 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
02/28/2025
02/28/2025
Sell
-732,827 @ $260.00
($190,535,020) 8,068,411 (-8.33%) Indirect - See Footnotes
12/09/2024
12/10/2024
Sell
-1,037,017 @ $187.27
($194,200,043) 8,740,387 (-10.61%) Indirect - See Footnotes

KALA BIO, Inc. - KALA

10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$2.00 M
310,559 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
12/30/2024
12/31/2024
Buy
310,559 @ $6.44
$2,000,000 1,083,398 (40.18%) Indirect - See Footnotes

Bicycle Therapeutics Plc - BCYC

Director 10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
2
$21.23 M
1,485,397 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
12/16/2024
12/17/2024
Buy
500,000 @ $15.34
$7,670,900 9,995,274 (5.27%) Indirect - See Footnotes
12/13/2024
12/17/2024
Buy
985,397 @ $13.76
$13,559,485 9,537,643 (11.52%) Indirect - See Footnotes