Orbimed Advisors Llc

EDGAR CIK 0001055951

Sionna Therapeutics, Inc. - SION

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
0
$0
0 Shares
Indirect Sells
20
($55.67) M
-1,235,000 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
07/07/2026
10b5-1
07/09/2026
Sell
-85,918 @ $44.86
 ($3,854,281) 2,469,959 (-3.36%) Indirect - See footnotes
06/30/2026
10b5-1
07/02/2026
Sell
-115,844 @ $45.50
 ($5,270,902) 2,555,877 (-4.34%) Indirect - See footnotes
05/27/2026
10b5-1
05/29/2026
Sell
-101 @ $44.49
 ($4,493) 2,671,721 (-0.00%) Indirect - See footnotes
05/11/2026
10b5-1
05/11/2026
Sell
-184,639 @ $46.22
 ($8,534,015) 2,671,822 (-6.46%) Indirect - See footnotes(
05/08/2026
10b5-1
05/11/2026
Sell
-59,767 @ $44.58
 ($2,664,413) 2,856,461 (-2.05%) Indirect - See footnotes(
05/07/2026
10b5-1
05/11/2026
Sell
-48,546 @ $44.61
 ($2,165,637) 2,916,228 (-1.64%) Indirect - See footnotes(
04/18/2026
10b5-1
04/21/2026
Sell
-2,948 @ $44.52
 ($131,245) 2,964,774 (-0.10%) Indirect - See footnotes
04/17/2026
10b5-1
04/21/2026
Sell
-52,397 @ $44.68
 ($2,341,098) 2,967,722 (-1.73%) Indirect - See footnotes
04/16/2026
10b5-1
04/16/2026
Sell
-226,906 @ $45.34
 ($10,287,918) 3,020,119 (-6.99%) Indirect - See footnotes
04/15/2026
10b5-1
04/16/2026
Sell
-235,863 @ $44.64
 ($10,528,924) 3,247,025 (-6.77%) Indirect - See footnotes
04/14/2026
10b5-1
04/16/2026
Sell
-47,814 @ $44.51
 ($2,128,201) 3,482,888 (-1.35%) Indirect - See footnotes
02/03/2026
02/04/2026
Sell
-29,063 @ $44.58
 ($1,295,629) 3,530,702 (-0.82%) Indirect - See footnotes
02/02/2026
02/04/2026
Sell
-1,890 @ $44.57
 ($84,237) 3,559,765 (-0.05%) Indirect - See footnotes
12/24/2025
12/29/2025
Sell
-33,356 @ $44.55
 ($1,486,010) 3,561,655 (-0.93%) Indirect - See footnotes
12/19/2025
12/19/2025
Sell
-875 @ $44.49
 ($38,929) 3,595,011 (-0.02%) Indirect - See footnotes
12/18/2025
12/19/2025
Sell
-100 @ $44.49
 ($4,449) 3,595,886 (-0.00%) Indirect - See footnotes
12/17/2025
12/19/2025
Sell
-900 @ $44.50
 ($40,050) 3,595,986 (-0.03%) Indirect - See footnotes
11/26/2025
11/26/2025
Sell
-1,600 @ $44.49
 ($71,184) 3,596,886 (-0.04%) Indirect - See footnotes
11/25/2025
11/26/2025
Sell
-11,890 @ $44.60
 ($530,294) 3,598,486 (-0.33%) Indirect - See footnotes
11/24/2025
11/26/2025
Sell
-94,583 @ $44.54
 ($4,212,727) 3,610,376 (-2.55%) Indirect - See footnotes

Enliven Therapeutics, Inc. - ELVN

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
0
$0
0 Shares
Indirect Sells
2
($51.68) M
-1,141,531 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
06/22/2026
06/24/2026
Sell
-860,123 @ $45.36
 ($39,014,046) 6,555,102 (-11.60%) Indirect - See Footnotes
06/15/2026
06/17/2026
Sell
-281,408 @ $45.02
 ($12,668,988) 7,388,902 (-3.67%) Indirect - See Footnotes

Q32 Bio Inc. - QTTB

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director 10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$15.00 M
1,875,000 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
05/28/2026
06/01/2026
Buy
1,875,000 @ $8.00
 $15,000,000 625,000 (-150.00%) Indirect - See footnotes

Prelude Therapeutics Inc - PRLD

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director 10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$12.50 M
2,815,315 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
04/21/2026
04/23/2026
Buy
2,815,315 @ $4.44
 $12,499,999 1,126,126 (-166.67%) Indirect - See footnotes

Traws Pharma, Inc. - TRAW

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$998,207
597,729 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
04/16/2026
04/28/2026
Buy
597,729 @ $1.67
 $998,207 1,203,250 (98.71%) Indirect - See Footnote

Adicet Bio, Inc. - ACET

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$5.00 M
5,000,000 Shares
Indirect Sells
2
($674,847)
-104,658 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
04/08/2026
04/09/2026
Sell
-72,939 @ $6.42
 ($468,082) 0 (-100.00%) Indirect - See footnotes
04/07/2026
04/09/2026
Sell
-31,719 @ $6.52
 ($206,765) 32,523 (-49.37%) Indirect - See footnotes
10/08/2025
10/10/2025
Buy
5,000,000 @ $1.00
 $5,000,000 4,490,254 (-980.88%) Indirect - See footnotes

Pmv Pharmaceuticals, Inc. - PMVP

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
10% owner
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
0
$0
0 Shares
Indirect Sells
2
($2.42) M
-1,500,000 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
10/23/2025
10/27/2025
Sell
-1,000,000 @ $1.52
 ($1,520,000) 4,975,291 (-16.74%) Indirect - See Footnotes
09/10/2025
09/12/2025
Sell
-500,000 @ $1.80
 ($900,000) 5,975,291 (-7.72%) Indirect - See Footnotes

Shattuck Labs, Inc. - STTK

  1. Manufacturing
  2. Chemicals
  3. Pharmaceutical Preparations
Director
Direct Buys
0
$0
0 Shares
Direct Sells
0
$0
0 Shares
Indirect Buys
1
$5.47 M
6,306,127 Shares
Indirect Sells
0
$0
0 Shares
Monthly Values

Transaction Filed Type Shares @ Price Value Balance ( Change % ) Ownership
08/25/2025
09/02/2025
Buy
6,306,127 @ $0.87
 $5,471,826 1,051,021 (-120.00%) Indirect - See Footnote