Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 9/9/2025 10:04:53 PM
1 Month
Buy/Sell Ratio 2.91
74%
26%
Buy Sell
$458.71 M ($157.61) M
42 Insiders 155 Insiders
66 Transactions 243 Transactions
8/9/2025 to 9/9/2025
3 Month
Buy/Sell Ratio 2.34
70%
30%
Buy Sell
$590.78 M ($252.49) M
124 Insiders 319 Insiders
340 Transactions 549 Transactions
6/9/2025 to 9/9/2025
6 Month
Buy/Sell Ratio 1.86
64%
36%
Buy Sell
$759.88 M ($409.25) M
263 Insiders 473 Insiders
906 Transactions 1024 Transactions
3/9/2025 to 9/9/2025
12 Month
Buy/Sell Ratio 0.72
41%
59%
Buy Sell
$1,115.86 M ($1,558.48) M
435 Insiders 799 Insiders
1612 Transactions 2320 Transactions
9/9/2024 to 9/9/2025

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Bausch Health Companies Inc.
$369,628,560 8
Janux Therapeutics, Inc.
$79,042,965 4
Madrigal Pharmaceuticals, Inc.
$61,921,024 3
Zymeworks Inc.
$58,036,053 36
89Bio, Inc.
$49,999,994 1
Mineralys Therapeutics, Inc.
$47,499,981 2
Aurinia Pharmaceuticals Inc.
$37,125,126 9
Tyra Biosciences, Inc.
$35,156,072 7
Viridian Therapeutics, Inc.\De
$30,000,000 1
Larimar Therapeutics, Inc.
$30,000,000 3

Most Insider Selling

12 months
Name Value Transactions
BeOne Medicines Ltd.
($384,735,063) 2
Nuvalent, Inc.
($110,000,000) 1
MoonLake Immunotherapeutics
($100,003,200) 1
Nuvalent, Inc.
($97,750,000) 1
Roivant Sciences Ltd.
($51,232,227) 5
Bridgebio Pharma, Inc.
($42,773,577) 19
Dyne Therapeutics, Inc.
($23,660,659) 25
Abbvie Inc.
($20,263,020) 2
Disc Medicine, Inc.
($20,108,066) 7
Disc Medicine, Inc.
($20,108,066) 7

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Eli Lilly & Co 8 8
Perspective Therapeutics, Inc. 6 9
Hcw Biologics Inc. 6 8
Avadel Pharmaceuticals Plc 6 7
Organon & Co. 6 6
CalciMedica, Inc. 5 7
Zomedica Corp. 5 7
Relmada Therapeutics, Inc. 4 13
Maia Biotechnology, Inc. 4 13
Immunome Inc. 4 10

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Ani Pharmaceuticals Inc 14 29
Apellis Pharmaceuticals, Inc. 12 36
Blueprint Medicines Corp 11 27
Ionis Pharmaceuticals Inc 11 26
Xencor Inc 11 16
Uniqure N.V. 10 16
Puma Biotechnology, Inc. 10 13
Insmed Inc 9 62
Ptc Therapeutics, Inc. 9 36
Disc Medicine, Inc. 9 34

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Bausch Health Companies Inc. 1519.70 $333,757,793 ($219,621) 1683.03 $369,628,560 ($219,621) 1655.34 $369,628,560 ($223,295)
Alx Oncology Holdings Inc 30.47 $58,402 ($1,917) 16.78 $58,402 ($3,481) 3.33 $104,806 ($31,433)
Madrigal Pharmaceuticals, Inc. 9.14 $61,921,024 ($6,771,124) 9.03 $61,921,024 ($6,854,468) 4.86 $61,921,024 ($12,748,745)
Evolus, Inc. 4.76 $204,486 ($42,972) 0.11 $393,486 ($3,744,852) 0.10 $393,486 ($3,900,468)
Eli Lilly & Co 2.90 $4,409,388 ($1,518,692) 1.14 $4,537,301 ($3,989,892) 0.50 $4,537,301 ($9,028,999)
Rocket Pharmaceuticals, Inc. 0.32 $34,100 ($107,139) 0.98 $234,865 ($240,511) 0.24 $234,865 ($961,614)
Aldeyra Therapeutics, Inc. 0.12 $13,250 ($113,713) 0.12 $13,250 ($113,713) 0.12 $13,250 ($113,713)
Axsome Therapeutics, Inc. 0.01 $200,466 ($13,373,843) 0.01 $200,466 ($14,479,691) 0.01 $200,466 ($14,479,691)
NewAmsterdam Pharma Co N.V. 0.00 $11,294 ($3,130,659) 0.09 $273,662 ($3,130,659) 0.12 $375,198 ($3,130,659)
Ani Pharmaceuticals Inc 0.00 $0 ($32,028,513) 0.00 $0 ($32,626,601) 0.00 $0 ($33,704,423)
Liquidia Corp 0.00 $0 ($20,409,392) 0.00 $0 ($21,652,765) 0.13 $2,999,994 ($22,831,412)
Bridgebio Pharma, Inc. 0.00 $0 ($10,814,566) 0.00 $0 ($43,292,352) 0.00 $0 ($68,305,936)
Alnylam Pharmaceuticals, Inc. 0.00 $0 ($8,316,986) 0.00 $0 ($8,325,369) 0.00 $1,211 ($16,696,989)
Amneal Pharmaceuticals, Inc. 0.00 $0 ($7,744,386) 0.00 $0 ($10,443,394) 0.00 $0 ($16,778,550)
Insmed Inc 0.00 $0 ($6,973,749) 0.01 $201,694 ($16,167,806) 0.00 $201,694 ($48,479,507)
Apellis Pharmaceuticals, Inc. 0.00 $0 ($6,507,129) 0.00 $0 ($6,703,272) 0.00 $0 ($11,131,233)
Ionis Pharmaceuticals Inc 0.00 $0 ($5,717,409) 0.07 $477,900 ($6,817,290) 0.07 $658,979 ($9,795,062)
Design Therapeutics, Inc. 0.00 $0 ($2,953,792) 0.00 $0 ($2,953,792) 0.00 $0 ($2,977,655)
Corcept Therapeutics Inc 0.00 $0 ($2,821,033) 0.00 $0 ($17,302,835) 0.00 $0 ($17,707,591)
Bristol Myers Squibb Co 0.00 $0 ($2,650,480) 0.08 $202,215 ($2,654,167) 0.19 $512,340 ($2,693,097)
Wave Life Sciences Ltd. 0.00 $0 ($2,380,003) 0.00 $0 ($2,640,994) 0.00 $0 ($4,886,089)
Disc Medicine, Inc. 0.00 $0 ($2,105,862) 0.00 $0 ($46,450,045) 0.00 $0 ($47,408,412)
Sionna Therapeutics, Inc. 0.00 $0 ($1,966,634) 0.00 $0 ($1,966,634) 0.00 $0 ($1,966,634)
Stoke Therapeutics, Inc. 0.00 $0 ($1,863,709) 0.00 $0 ($2,583,750) 0.00 $0 ($3,272,392)
Akero Therapeutics, Inc. 0.00 $0 ($1,457,596) 0.86 $8,787,921 ($10,276,168) 1.03 $18,387,921 ($17,827,448)
ARS Pharmaceuticals, Inc. 0.00 $0 ($1,428,100) 0.00 $0 ($1,428,100) 0.00 $0 ($13,628,873)
Supernus Pharmaceuticals, Inc. 0.00 $0 ($1,336,101) 0.00 $0 ($1,336,101) 0.00 $0 ($1,652,535)
Xeris Biopharma Holdings, Inc. 0.00 $0 ($1,095,685) 0.08 $109,475 ($1,312,929) 0.08 $109,475 ($1,312,929)
Cytokinetics Inc 0.00 $0 ($878,340) 0.00 $0 ($6,767,173) 0.00 $0 ($9,651,622)
Skye Bioscience, Inc. 0.00 $0 ($800,548) 0.00 $0 ($800,548) 0.00 $0 ($3,447,334)
Harmony Biosciences Holdings, Inc. 0.00 $0 ($787,378) 0.00 $0 ($1,014,764) 0.00 $0 ($2,289,310)
Jazz Pharmaceuticals Plc 0.00 $0 ($771,690) 5.12 $9,993,082 ($1,953,163) 1.78 $9,993,082 ($5,607,491)
Eton Pharmaceuticals, Inc. 0.00 $0 ($673,714) 0.00 $0 ($4,770,642) 0.00 $0 ($4,770,642)
Collegium Pharmaceutical, Inc 0.00 $0 ($671,576) 0.00 $0 ($2,797,320) 0.00 $0 ($3,883,201)
Arcutis Biotherapeutics, Inc. 0.00 $0 ($649,966) 0.16 $373,039 ($2,268,848) 0.09 $407,062 ($4,736,765)
Nektar Therapeutics 0.00 $0 ($627,568) 0.00 $0 ($656,992) 0.00 $0 ($957,830)
Acadia Pharmaceuticals Inc 0.00 $0 ($595,584) 0.00 $0 ($1,050,218) 0.00 $0 ($1,139,892)
Arrowhead Pharmaceuticals, Inc. 0.00 $0 ($575,000) 0.00 $0 ($2,883,311) 0.00 $0 ($6,754,759)
Ardelyx, Inc. 0.00 $0 ($507,463) 4.01 $3,403,196 ($848,166) 3.47 $6,777,784 ($1,951,502)
Enliven Therapeutics, Inc. 0.00 $0 ($498,466) 0.00 $0 ($3,681,088) 0.00 $0 ($7,247,969)
Natures Sunshine Products Inc 0.00 $0 ($409,803) 0.00 $0 ($409,803) 0.00 $0 ($409,803)
Ocular Therapeutix, Inc 0.00 $0 ($367,864) 0.10 $69,600 ($688,184) 0.05 $69,600 ($1,281,936)
Agios Pharmaceuticals, Inc. 0.00 $0 ($315,091) 0.00 $0 ($315,091) 0.00 $0 ($1,494,167)
Spyre Therapeutics, Inc. 0.00 $0 ($299,639) 0.00 $0 ($299,639) 0.00 $0 ($556,881)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($246,148) 0.07 $37,005 ($507,927) 0.15 $138,373 ($923,861)
Protagonist Therapeutics, Inc 0.00 $0 ($237,000) 0.00 $0 ($3,985,353) 0.00 $0 ($4,268,068)
Crinetics Pharmaceuticals, Inc. 0.00 $0 ($189,437) 0.00 $0 ($1,310,792) 0.00 $0 ($1,968,111)
Urogen Pharma Ltd. 0.00 $0 ($176,900) 0.00 $0 ($176,900) 0.00 $0 ($176,900)
Abeona Therapeutics Inc. 0.00 $0 ($143,041) 0.00 $0 ($1,768,075) 0.00 $0 ($1,809,995)
Lyell Immunopharma, Inc. 0.00 $0 ($133,557) 3.35 $447,931 ($133,557) 3.35 $447,931 ($133,557)
Emergent Biosolutions Inc. 0.00 $0 ($130,684) 0.79 $349,800 ($441,451) 0.40 $349,800 ($885,216)
Rapport Therapeutics, Inc. 0.00 $0 ($127,466) 0.27 $162,238 ($594,727) 0.27 $162,238 ($594,727)
Kiniksa Pharmaceuticals International, plc 0.00 $0 ($124,397) 0.00 $0 ($494,872) 0.00 $0 ($494,872)
Dyne Therapeutics, Inc. 0.00 $0 ($108,039) 4.07 $911,000 ($223,622) 0.04 $911,000 ($25,054,538)
Vertex Pharmaceuticals Inc / Ma 0.00 $0 ($102,860) 0.85 $5,844,183 ($6,860,565) 0.20 $5,844,183 ($29,100,296)
Cadrenal Therapeutics, Inc. 0.00 $0 ($98,348) 0.00 $0 ($98,348) 0.00 $0 ($98,348)
Ptc Therapeutics, Inc. 0.00 $0 ($83,600) 0.00 $0 ($1,842,552) 0.00 $0 ($4,292,868)
Aquestive Therapeutics, Inc. 0.00 $0 ($79,500) 0.00 $0 ($79,500) 0.00 $0 ($79,714)
Ligand Pharmaceuticals Inc 0.00 $0 ($75,775) 2.45 $1,156,546 ($472,424) 0.81 $1,156,546 ($1,424,941)
Pacira Biosciences, Inc. 0.00 $0 ($64,005) 0.00 $0 ($703,698) 0.00 $0 ($736,182)
Cryoport, Inc. 0.00 $0 ($43,000) 0.00 $0 ($331,589) 0.00 $0 ($347,789)
BeOne Medicines Ltd. 0.00 $0 ($39,865) 0.00 $0 ($16,025,324) 0.00 $0 ($410,905,407)
Q32 Bio Inc. 0.00 $0 ($31,921) 0.00 $0 ($31,921) 0.00 $0 ($31,921)
Arcus Biosciences, Inc. 0.00 $0 ($18,758) 0.00 $0 ($18,758) 5.32 $402,665 ($75,747)
Travere Therapeutics, Inc. 0.00 $0 ($18,744) 0.00 $0 ($31,315) 0.00 $0 ($2,489,332)
Spero Therapeutics, Inc. 0.00 $0 ($16,286) 0.00 $0 ($16,286) 0.00 $0 ($304,681)
Amphastar Pharmaceuticals, Inc. 0.00 $0 ($15,492) 0.00 $0 ($76,708) 0.00 $0 ($104,694)
Ironwood Pharmaceuticals Inc 0.00 $0 ($11,072) 0.00 $0 ($20,303) 0.00 $0 ($515,389)
Avidity Biosciences, Inc. 0.00 $0 ($8,915) 0.00 $0 ($3,569,528) 0.00 $0 ($10,467,469)
Phathom Pharmaceuticals, Inc. 0.00 $0 ($5,573) 7.16 $261,173 ($36,465) 1.59 $441,505 ($276,949)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($2,637) 0.00 $0 ($121,461) 0.00 $0 ($8,233,714)
Karyopharm Therapeutics Inc. 0.00 $0 ($81) 0.00 $0 ($7,050) 0.00 $0 ($187,328)
Mineralys Therapeutics, Inc. -- $44,999,978 $0 37.93 $74,099,970 ($1,953,623) 28.83 $74,099,970 ($2,570,006)
Shattuck Labs, Inc. -- $10,943,653 $0 -- $10,943,653 $0 -- $10,987,873 $0
Kura Oncology, Inc. -- $713,346 $0 37.41 $713,346 ($19,069) 3.45 $713,346 ($206,659)
Perrigo Co Plc -- $328,259 $0 -- $522,875 $0 0.70 $522,875 ($741,940)
Viatris Inc -- $219,740 $0 -- $756,002 $0 0.28 $756,002 ($2,681,403)
Relmada Therapeutics, Inc. -- $178,095 $0 -- $639,406 $0 -- $1,012,707 $0
Precigen, Inc. -- $167,643 $0 -- $167,643 $0 -- $167,643 $0
Macrogenics Inc -- $150,515 $0 -- $150,515 $0 -- $150,515 $0
CalciMedica, Inc. -- $96,361 $0 55.60 $202,945 ($3,650) 299.02 $1,091,413 ($3,650)
Zomedica Corp. -- $61,743 $0 -- $393,999 $0 -- $497,039 $0
Gossamer Bio, Inc. -- $50,016 $0 -- $50,016 $0 -- $50,016 $0
ZEVRA THERAPEUTICS, INC. -- $45,825 $0 0.58 $127,801 ($221,004) 0.12 $131,758 ($1,140,979)
Dynavax Technologies Corp -- $41,116 $0 0.22 $41,116 ($190,392) 0.06 $41,116 ($661,866)
Tonix Pharmaceuticals Holding Corp. -- $24,061 $0 -- $110,261 $0 -- $110,261 $0
Teva Pharmaceutical Industries Ltd -- $20,988 $0 0.00 $20,988 ($7,049,769) 0.00 $20,988 ($16,230,364)
Arcturus Therapeutics Holdings Inc. -- $20,499 $0 -- $20,499 $0 0.08 $20,499 ($249,121)
Akari Therapeutics Plc -- $19,540 $0 -- $56,660 $0 -- $56,660 $0
Renovorx, Inc. -- $9,296 $0 -- $158,086 $0 -- $158,086 $0
Annexon, Inc. -- $8,600 $0 3.60 $28,723 ($7,987) 0.32 $64,883 ($200,255)
Bespoke Extracts, Inc. -- $975 $0 -- $2,065 $0 -- $5,310 $0
Arvinas, Inc. -- $0 $0 0.00 $0 ($137,096) 0.00 $0 ($908,698)
Aurinia Pharmaceuticals Inc. -- $0 $0 64.71 $13,590,000 ($210,000) 6.03 $37,125,126 ($6,156,646)
Greenwich Lifesciences, Inc. -- $0 $0 -- $164,835 $0 -- $401,174 $0
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($129,840) 0.00 $0 ($300,311)
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($630,447) 0.00 $0 ($826,288)
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($198,691) 0.00 $0 ($885,909)
KALA BIO, Inc. -- $0 $0 0.00 $0 ($203,515) 0.00 $0 ($276,046)
Zentalis Pharmaceuticals, Inc. -- $0 $0 -- $29,373 $0 3.58 $252,786 ($70,569)
Verastem, Inc. -- $0 $0 0.00 $0 ($709,194) 0.00 $0 ($775,725)
Kezar Life Sciences, Inc. -- $0 $0 0.00 $0 ($3,531) 0.00 $0 ($3,531)
United Therapeutics Corp -- $0 $0 0.00 $0 ($187,045) 0.00 $0 ($1,284,036)
Anixa Biosciences Inc -- $0 $0 -- $139,200 $0 -- $325,241 $0
Cartesian Therapeutics, Inc. -- $0 $0 -- $2,893,671 $0 26.05 $15,892,118 ($610,064)
Cumberland Pharmaceuticals Inc -- $0 $0 -- $33,530 $0 -- $74,082 $0
Tg Therapeutics, Inc. -- $0 $0 0.00 $0 ($369,400) 0.00 $0 ($2,395,457)
2Seventy Bio, Inc. -- $0 $0 0.00 $0 ($49,361) 0.00 $0 ($455,049)
Hookipa Pharma Inc. -- $0 $0 0.00 $0 ($39,362) 0.00 $0 ($39,362)
Galectin Therapeutics Inc -- $0 $0 -- $17,420 $0 -- $84,035 $0
Entrada Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,088,222) 0.00 $0 ($1,854,774)
Biomarin Pharmaceutical Inc -- $0 $0 0.00 $0 ($216,269) 0.00 $0 ($1,159,851)
Tharimmune, Inc. -- $0 $0 -- $593,424 $0 -- $628,143 $0
Repare Therapeutics Inc. -- $0 $0 0.00 $0 ($42,488) 0.00 $0 ($42,488)
Xenon Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($91) 0.00 $0 ($91)
Zai Lab Ltd -- $0 $0 0.00 $0 ($1,855,907) 0.00 $0 ($2,917,943)
Regulus Therapeutics Inc. -- $0 $0 -- $95,852 $0 0.55 $170,899 ($310,669)
Uniqure N.V. -- $0 $0 0.00 $0 ($322,426) 0.00 $0 ($1,396,278)
89Bio, Inc. -- $0 $0 0.00 $0 ($206,488) 99.68 $50,302,794 ($504,632)
Mannkind Corp -- $0 $0 0.00 $0 ($1,172,660) 0.00 $0 ($1,576,360)
Checkpoint Therapeutics, Inc. -- $0 $0 0.00 $0 ($110,868) 0.00 $0 ($4,598,055)
Verona Pharma Plc -- $0 $0 0.00 $0 ($18,265,688) 0.01 $476,066 ($40,973,453)
Syndax Pharmaceuticals Inc -- $0 $0 2.95 $241,896 ($81,987) 0.58 $241,896 ($418,160)
Abbvie Inc. -- $0 $0 0.00 $0 ($6,385,746) 0.00 $0 ($32,264,257)
Lifevantage Corp -- $0 $0 -- $15,886 $0 0.06 $23,136 ($364,620)
Vera Therapeutics, Inc. -- $0 $0 -- $5,277,311 $0 2.69 $5,277,311 ($1,963,640)
Rhythm Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,521,444) 0.00 $0 ($1,948,121)
GYRE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($388,047) 0.00 $0 ($1,546,917)
Zoetis Inc. -- $0 $0 0.00 $0 ($367,289) 0.00 $0 ($367,289)
Abbott Laboratories -- $0 $0 0.00 $0 ($1,083,874) 0.00 $0 ($1,969,919)
Alkermes Plc. -- $0 $0 0.00 $0 ($210,143) 0.00 $0 ($1,403,137)
Abcellera Biologics Inc. -- $0 $0 -- $57,500 $0 -- $198,068 $0
Aprea Therapeutics, Inc. -- $0 $0 -- $10,110 $0 5.95 $176,052 ($29,583)
Altimmune, Inc. -- $0 $0 -- $57,780 $0 -- $57,780 $0
Vanda Pharmaceuticals Inc. -- $0 $0 5.29 $169,967 ($32,130) 8.86 $513,636 ($57,993)
Theravance Biopharma, Inc. -- $0 $0 0.00 $0 ($413,870) 0.00 $0 ($485,870)
Elanco Animal Health Inc -- $0 $0 -- $102,000 $0 -- $483,558 $0
Blueprint Medicines Corp -- $0 $0 0.00 $0 ($1,517,612) 0.00 $0 ($9,573,626)
Xencor Inc -- $0 $0 0.00 $0 ($726,467) 0.00 $0 ($1,026,719)
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 0.00 $0 ($30,561) 0.00 $0 ($160,802)
Kalvista Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($992,221) 0.00 $0 ($992,221)
Organogenesis Holdings Inc. -- $0 $0 -- $725,290 $0 0.57 $725,290 ($1,273,959)
Immuneering Corp -- $0 $0 -- $334,058 $0 -- $334,058 $0
Iterum Therapeutics Plc -- $0 $0 -- $10,854 $0 -- $10,854 $0
Optinose, Inc. -- $0 $0 0.00 $0 ($3,445) 0.00 $0 ($65,416)
Johnson & Johnson -- $0 $0 0.00 $0 ($3,129,830) 0.05 $147,220 ($3,129,830)
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($79,600) 0.00 $0 ($155,787)
XOMA Royalty Corp -- $0 $0 -- $748,875 $0 -- $760,508 $0
Oric Pharmaceuticals, Inc. -- $0 $0 0.43 $262,899 ($617,394) 0.43 $262,899 ($617,394)
Assembly Biosciences, Inc. -- $0 $0 0.00 $0 ($14,664) 2.43 $49,998 ($20,558)
Igm Biosciences, Inc. -- $0 $0 0.00 $0 ($68,329) 0.00 $0 ($238,021)
Alzamend Neuro, Inc. -- $0 $0 0.16 $21,072 ($134,366) 0.16 $21,072 ($134,366)
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,520) 0.00 $0 ($2,520)
Synlogic, Inc. -- $0 $0 0.00 $0 ($173) 0.00 $0 ($3,086)
Nuvation Bio Inc. -- $0 $0 -- $2,091,111 $0 14.19 $2,311,111 ($162,883)
Longeveron Inc. -- $0 $0 0.00 $0 ($36,757) 0.00 $0 ($39,345)
Heron Therapeutics, Inc. /De/ -- $0 $0 -- $2,649,819 $0 -- $2,649,819 $0
Bicycle Therapeutics Plc -- $0 $0 0.00 $0 ($161,777) 24.82 $21,230,385 ($855,268)
Fibrogen Inc -- $0 $0 -- $275,188 $0 -- $275,188 $0
Nkarta, Inc. -- $0 $0 0.00 $0 ($3,204) 0.00 $0 ($110,751)
Neurogene Inc. -- $0 $0 0.00 $0 ($179,250) 8.15 $1,460,400 ($179,250)
Anaptysbio, Inc -- $0 $0 0.00 $0 ($144,539) 7.61 $1,099,642 ($144,539)
Savara Inc -- $0 $0 -- $535,647 $0 3.04 $882,319 ($290,675)
Phio Pharmaceuticals Corp. -- $0 $0 -- $27,011 $0 -- $27,011 $0
Immunic, Inc. -- $0 $0 -- $246,928 $0 -- $347,297 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $124,750 $0 -- $133,150 $0
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($151,020) 0.00 $0 ($1,696,872)
Mirum Pharmaceuticals, Inc. -- $0 $0 0.47 $123,732 ($262,433) 0.15 $284,418 ($1,911,152)
Edgewise Therapeutics, Inc. -- $0 $0 -- $20,000,000 $0 98.72 $20,000,000 ($202,603)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($47,888) 0.00 $0 ($47,888)
Pmv Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($152,104) 0.00 $0 ($167,304)
Prelude Therapeutics Inc -- $0 $0 -- $650,621 $0 -- $876,166 $0
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($12,680) 0.00 $0 ($12,680)
Cogent Biosciences, Inc. -- $0 $0 -- $24,999,993 $0 -- $25,332,406 $0
Werewolf Therapeutics, Inc. -- $0 $0 -- $487,188 $0 -- $487,188 $0
Therapeuticsmd, Inc. -- $0 $0 -- $2,809 $0 -- $2,809 $0
CervoMed Inc. -- $0 $0 -- $35,811 $0 -- $35,811 $0
Silo Pharma, Inc. -- $0 $0 -- $4,329 $0 -- $11,051 $0
Immunome Inc. -- $0 $0 -- $1,268,079 $0 -- $3,740,590 $0
Opko Health, Inc. -- $0 $0 -- $2,012,418 $0 -- $5,187,381 $0
Kronos Bio, Inc. -- $0 $0 0.00 $0 ($21,554) 0.00 $0 ($21,554)
Centessa Pharmaceuticals Plc -- $0 $0 3.11 $5,865,242 ($1,886,244) 0.79 $5,865,242 ($7,466,113)
Verrica Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($2,805) 0.00 $0 ($2,805)
Viking Therapeutics, Inc. -- $0 $0 0.03 $29,943 ($984,534) 0.00 $29,943 ($13,766,329)
Atai Life Sciences N.V. -- $0 $0 0.00 $0 ($246,038) 0.00 $0 ($246,038)
Larimar Therapeutics, Inc. -- $0 $0 -- $30,000,000 $0 -- $30,000,000 $0
Palatin Technologies Inc -- $0 $0 -- $10,180 $0 -- $10,180 $0
Jade Biosciences, Inc. -- $0 $0 -- $44,400 $0 -- $44,400 $0
Atossa Therapeutics, Inc. -- $0 $0 -- $16,887 $0 -- $16,887 $0
Hcw Biologics Inc. -- $0 $0 -- $3,045,056 $0 -- $3,045,056 $0
Rezolute, Inc. -- $0 $0 -- $4,153,618 $0 -- $4,304,935 $0
Catalyst Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,580,787) 0.00 $0 ($4,277,170)
Organon & Co. -- $0 $0 -- $651,626 $0 -- $651,626 $0
PALVELLA THERAPEUTICS, INC. -- $0 $0 -- $100,797 $0 -- $152,517 $0
Tyra Biosciences, Inc. -- $0 $0 24.38 $15,320,006 ($628,263) 4.13 $35,308,026 ($8,541,429)
Ventyx Biosciences, Inc. -- $0 $0 0.00 $0 ($2,019) 24.31 $1,260,462 ($51,860)
Context Therapeutics Inc. -- $0 $0 -- $107,086 $0 -- $107,086 $0
Xilio Therapeutics, Inc. -- $0 $0 -- $72,765 $0 -- $72,765 $0
Io Biotech, Inc. -- $0 $0 -- $20,884 $0 -- $75,761 $0
Sellas Life Sciences Group, Inc. -- $0 $0 -- $84,600 $0 -- $84,600 $0
Immix Biopharma, Inc. -- $0 $0 -- $10,069 $0 -- $114,427 $0
Ainos, Inc. -- $0 $0 0.00 $0 ($23,639) 0.00 $0 ($23,639)
Geron Corp -- $0 $0 -- $15,667 $0 -- $221,880 $0
AYTU BIOPHARMA, INC -- $0 $0 -- $124,998 $0 -- $144,498 $0
Oncotelic Therapeutics, Inc. -- $0 $0 -- $994 $0 -- $19,332 $0
Rockwell Medical, Inc. -- $0 $0 0.00 $0 ($20,310) 0.00 $0 ($108,846)
Unity Biotechnology, Inc. -- $0 $0 0.00 $0 ($142,878) 0.00 $0 ($145,942)
TALPHERA, INC. -- $0 $0 -- $125,000 $0 1109.04 $131,849 ($119)
Geovax Labs, Inc. -- $0 $0 -- $34,625 $0 -- $34,625 $0
Earth Science Tech, Inc. -- $0 $0 -- $65,949 $0 -- $402,383 $0
Perspective Therapeutics, Inc. -- $0 $0 -- $316,769 $0 -- $594,081 $0
Terns Pharmaceuticals, Inc. -- $0 $0 31.07 $186,595 ($6,006) 24.46 $5,311,161 ($217,097)
An2 Therapeutics, Inc. -- $0 $0 -- $20,798 $0 21.35 $504,135 ($23,610)
Lexaria Bioscience Corp. -- $0 $0 -- $49,085 $0 -- $167,477 $0
Rafael Holdings, Inc. -- $0 $0 -- $16,742,985 $0 -- $16,742,985 $0
Benitec Biopharma Inc. -- $0 $0 -- $11,911,736 $0 -- $13,258,726 $0
Accustem Sciences Inc. -- $0 $0 -- $124,479 $0 -- $162,579 $0
Pepgen Inc. -- $0 $0 -- $71,668 $0 14.42 $71,668 ($4,971)
Maia Biotechnology, Inc. -- $0 $0 -- $179,998 $0 -- $1,183,624 $0
Pasithea Therapeutics Corp. -- $0 $0 0.00 $0 ($792) 0.00 $0 ($792)
Journey Medical Corp -- $0 $0 0.00 $0 ($315,932) 0.00 $0 ($887,229)
Zymeworks Inc. -- $0 $0 -- $26,071,310 $0 -- $58,036,053 $0
Aspire Biopharma Holdings, Inc. -- $0 $0 1.00 $7,800 ($7,800) 1.00 $7,800 ($7,800)
AEON Biopharma, Inc. -- $0 $0 -- $84,550 $0 -- $84,550 $0
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 0.08 $9,640 ($115,800) 0.01 $9,640 ($678,105)
MetaVia Inc. -- $0 $0 -- $9,940 $0 -- $9,940 $0
GENELUX CORP -- $0 $0 0.00 $0 ($78,297) 0.00 $0 ($145,842)
JUPITER NEUROSCIENCES, INC. -- $0 $0 -- $4,439 $0 -- $4,439 $0
BullFrog AI Holdings, Inc. -- $0 $0 0.00 $0 ($150,630) 0.00 $0 ($283,110)
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $14,410 $0 -- $131,933 $0
ACELYRIN, Inc. -- $0 $0 0.00 $0 ($68,902) 0.00 $0 ($68,902)
Sagimet Biosciences Inc. -- $0 $0 0.00 $0 ($772,193) 0.00 $0 ($772,193)
Mural Oncology plc -- $0 $0 0.00 $0 ($42,206) 0.00 $0 ($177,234)
FibroBiologics, Inc. -- $0 $0 -- $16,800 $0 -- $16,800 $0
NEONC TECHNOLOGIES HOLDINGS, INC. -- $0 $0 -- $207,889 $0 -- $207,889 $0
Nika Pharmaceuticals, Inc -- $0 $0 0.00 $0 ($500,000) 0.00 $0 ($500,000)
ALUMIS INC. -- $0 $0 -- $1,909,889 $0 -- $1,909,889 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $1,499,988 $0 -- $1,499,988 $0
IMPACT BIOMEDICAL INC. -- $0 $0 0.00 $0 ($4,209,761) 0.00 $5,173 ($4,209,761)
Mbx Biosciences, Inc. -- $0 $0 -- $45,312 $0 -- $4,621,323 $0
Apimeds Pharmaceuticals US, Inc. -- $0 $0 -- $107,074 $0 -- $107,074 $0
Emmaus Life Sciences, Inc. -- $0 $0 -- $0 $0 -- $800 $0
Processa Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $9,889 $0
Avid Bioservices, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,785,375)
Day One Biopharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,470,534)
Y-Mabs Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,341,555)
Regeneron Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($104,878)
Syros Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 2.63 $321,920 ($122,320)
Catalent, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($305,931)
Olema Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,936,396)
Enanta Pharmaceuticals Inc -- $0 $0 -- $0 $0 2.02 $256,050 ($126,993)
Clearside Biomedical, Inc. -- $0 $0 -- $0 $0 -- $50,300 $0
LIFECORE BIOMEDICAL, INC. \DE\ -- $0 $0 -- $0 $0 -- $5,473,959 $0
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $100,600 $0
Bolt Biotherapeutics, Inc. -- $0 $0 -- $0 $0 -- $2,482 $0
Clene Inc. -- $0 $0 -- $0 $0 -- $583,390 $0
Viridian Therapeutics, Inc.\De -- $0 $0 -- $0 $0 -- $30,616,312 $0
Chimerix Inc -- $0 $0 -- $0 $0 0.00 $0 ($91,140)
Nuvectis Pharma, Inc. -- $0 $0 -- $0 $0 5.75 $129,305 ($22,478)
Aclaris Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $1,499,998 $0
Nuvalent, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($214,838,222)
Tvardi Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,365)
Roivant Sciences Ltd. -- $0 $0 -- $0 $0 0.00 $0 ($57,098,536)
Generation Bio Co. -- $0 $0 -- $0 $0 -- $203,209 $0
Ibio, Inc. -- $0 $0 -- $0 $0 -- $654,995 $0
Protokinetix, Inc. -- $0 $0 -- $0 $0 -- $20,000 $0
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($94,797)
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($1,319)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 -- $69,950 $0
Schrodinger, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($257,884)
Alaunos Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,022)
KIORA PHARMACEUTICALS INC -- $0 $0 -- $0 $0 -- $15,400 $0
Avalo Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $12,750 $0
Bioxcel Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($18,173)
Cue Biopharma, Inc. -- $0 $0 -- $0 $0 -- $30,900 $0
Arbutus Biopharma Corp -- $0 $0 -- $0 $0 0.00 $0 ($251,655)
Phibro Animal Health Corp -- $0 $0 -- $0 $0 -- $110,500 $0
ALT5 Sigma Corp -- $0 $0 -- $0 $0 -- $9,000 $0
Monopar Therapeutics -- $0 $0 -- $0 $0 -- $25,188 $0
Galera Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $499,979 $0
Vtv Therapeutics Inc. -- $0 $0 -- $0 $0 -- $83,812 $0
Essa Pharma Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,185)
IGC Pharma, Inc. -- $0 $0 -- $0 $0 -- $200,000 $0
Sarepta Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($205,400)
Veru Inc. -- $0 $0 -- $0 $0 -- $84,351 $0
MARINUS PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,733)
Vyne Therapeutics Inc. -- $0 $0 -- $0 $0 -- $43,800 $0
Marker Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $35,472 $0
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,501,298)
Fortress Biotech, Inc. -- $0 $0 -- $0 $0 -- $1,404,581 $0
Avenue Therapeutics, Inc. -- $0 $0 -- $0 $0 6.84 $1,250 ($183)
Pfizer Inc -- $0 $0 -- $0 $0 8.13 $527,312 ($64,825)
Merck & Co., Inc. -- $0 $0 -- $0 $0 1.10 $1,577,424 ($1,436,352)
Cormedix Inc. -- $0 $0 -- $0 $0 -- $14,985 $0
Equillium, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($77,733)
Janux Therapeutics, Inc. -- $0 $0 -- $0 $0 10.60 $79,042,965 ($7,459,389)
Pds Biotechnology Corp -- $0 $0 -- $0 $0 -- $50,001 $0
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 0.97 $4,971 ($5,141)
Revance Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($16,296)
Opus Genetics, Inc. -- $0 $0 -- $0 $0 -- $208,592 $0
Forte Biosciences, Inc. -- $0 $0 -- $0 $0 -- $124,998 $0
Acurx Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $170,000 $0
Nrx Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $46,800 $0
Pyxis Oncology, Inc. -- $0 $0 -- $0 $0 -- $10,900 $0
Atea Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.06 $81,498 ($1,257,630)
Rein Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $898 $0
Avadel Pharmaceuticals Plc -- $0 $0 -- $0 $0 -- $761,675 $0
Tango Therapeutics, Inc. -- $0 $0 -- $0 $0 0.52 $74,000 ($143,227)
Cassava Sciences Inc -- $0 $0 -- $0 $0 0.00 $0 ($15,480)
MoonLake Immunotherapeutics -- $0 $0 -- $0 $0 0.00 $0 ($109,189,320)
Maravai Lifesciences Holdings, Inc. -- $0 $0 -- $0 $0 8.65 $1,087,625 ($125,750)
Scynexis Inc -- $0 $0 -- $0 $0 -- $27,400 $0
Rigel Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($424,179)
Promis Neurosciences Inc. -- $0 $0 -- $0 $0 -- $270,345 $0
Rani Therapeutics Holdings, Inc. -- $0 $0 -- $0 $0 -- $49,967 $0
Anebulo Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $10,000,000 $0
Biohaven Ltd. -- $0 $0 -- $0 $0 -- $4,259,538 $0
Mereo Biopharma Group plc -- $0 $0 -- $0 $0 0.00 $0 ($1,342,846)
Flora Growth Corp. -- $0 $0 -- $0 $0 -- $6,455 $0
Serina Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $151,667 $0
Quoin Pharmaceuticals, Ltd. -- $0 $0 -- $0 $0 -- $616,200 $0
Entero Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($678)
BIOADAPTIVES, INC. -- $0 $0 -- $0 $0 -- $10,625 $0
Coya Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $106,393 $0
Bio Essence Corp -- $0 $0 -- $0 $0 0.00 $0 ($562,006)
MIRA PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($133,649)
Kairos Pharma, LTD. -- $0 $0 -- $0 $0 -- $9,828 $0
Contineum Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($117,598)
Zenas Biopharma, Inc. -- $0 $0 -- $0 $0 -- $2,472,186 $0
Bioage Labs, Inc. -- $0 $0 -- $0 $0 -- $4,430,395 $0
Septerna, Inc. -- $0 $0 -- $0 $0 -- $934,328 $0