Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 10/28/2026 10:01:44 PM
1 Month
Buy/Sell Ratio 0.12
10%
90%
Buy Sell
$4.60 M ($38.74) M
21 Insiders 80 Insiders
25 Transactions 96 Transactions
9/28/2026 to 10/28/2026
3 Month
Buy/Sell Ratio 0.10
9%
91%
Buy Sell
$55.57 M ($539.40) M
120 Insiders 308 Insiders
203 Transactions 498 Transactions
7/28/2026 to 10/28/2026
6 Month
Buy/Sell Ratio 0.26
20%
80%
Buy Sell
$301.29 M ($1,151.50) M
212 Insiders 517 Insiders
389 Transactions 1196 Transactions
4/28/2026 to 10/28/2026
12 Month
Buy/Sell Ratio 0.26
20%
80%
Buy Sell
$669.50 M ($2,546.75) M
381 Insiders 885 Insiders
867 Transactions 2750 Transactions
10/28/2025 to 10/28/2026

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Wave Life Sciences, Inc.
$54,631,065 4
Summit Therapeutics Inc.
$51,447,200 2
Summit Therapeutics Inc.
$51,447,200 2
CRESCENT BIOPHARMA, INC.
$30,612,625 2
ALUMIS INC.
$28,768,847 17
Aurinia Pharmaceuticals Inc.
$25,144,033 6
Larimar Therapeutics, Inc.
$25,000,000 4
Biohaven Ltd.
$24,999,998 1
Benitec Biopharma Inc.
$22,442,099 7
Kardigan, Inc.
$20,000,000 1

Most Insider Selling

12 months
Name Value Transactions
Roivant Sciences Ltd.
($154,472,307) 10
Roivant Sciences Ltd.
($147,382,307) 9
Dyne Therapeutics, Inc.
($129,095,797) 19
Cogent Biosciences, Inc.
($127,400,000) 1
Liquidia Corp
($125,050,198) 20
BeOne Medicines Ltd.
($120,892,072) 9
Septerna, Inc.
($63,452,500) 1
MoonLake Immunotherapeutics
($62,962,500) 1
Sionna Therapeutics, Inc.
($55,674,636) 20
Sionna Therapeutics, Inc.
($55,674,636) 20

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Elanco Animal Health Inc 7 11
Indivior Pharmaceuticals, Inc. 7 8
Rapport Therapeutics, Inc. 6 6
CervoMed Inc. 5 12
Hepion Pharmaceuticals, Inc. 5 11
Maia Biotechnology, Inc. 5 10
Braveheart Bio, Inc. 5 5
Zenas Biopharma, Inc. 4 15
Annexon, Inc. 4 11
Relmada Therapeutics, Inc. 4 10

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
TAKEDA PHARMACEUTICAL CO LTD 13 19
Vertex Pharmaceuticals Inc / Ma 12 52
Ani Pharmaceuticals Inc 12 44
Ionis Pharmaceuticals Inc 12 26
BeOne Medicines Ltd. 11 36
Uniqure N.V. 11 17
Arrowhead Pharmaceuticals, Inc. 10 20
Liquidia Corp 9 61
Ptc Therapeutics, Inc. 9 49
Insmed Inc 9 39

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Rapport Therapeutics, Inc. 3.09 $1,664,824 ($539,577) 0.21 $1,664,824 ($8,088,209) 0.13 $1,664,824 ($12,432,949)
Roivant Sciences Ltd. 0.00 $0 ($7,022,668) 0.00 $0 ($113,220,201) 0.00 $0 ($319,311,120)
Liquidia Corp 0.00 $0 ($6,516,951) 0.00 $0 ($159,707,079) 0.00 $0 ($170,930,299)
PALVELLA THERAPEUTICS, INC. 0.00 $0 ($3,579,476) 0.00 $0 ($7,746,622) 0.11 $849,974 ($7,746,622)
Disc Medicine, Inc. 0.00 $0 ($3,351,274) 0.00 $0 ($7,854,271) 0.00 $0 ($12,957,634)
Opus Genetics, Inc. 0.00 $0 ($2,974,373) 0.00 $0 ($10,583,171) 0.02 $323,693 ($19,565,480)
Mineralys Therapeutics, Inc. 0.00 $0 ($1,909,665) 0.00 $0 ($7,167,010) 0.14 $8,762,797 ($62,873,373)
Jazz Pharmaceuticals Plc 0.00 $0 ($1,854,780) 0.00 $0 ($11,031,559) 0.00 $0 ($20,862,431)
Spyre Therapeutics, Inc. 0.00 $0 ($1,380,105) 0.00 $0 ($15,516,610) 0.00 $0 ($19,326,701)
Corcept Therapeutics Inc 0.00 $0 ($1,148,083) 0.00 $0 ($23,618,569) 0.10 $3,313,809 ($31,832,450)
MapLight Therapeutics, Inc. 0.00 $0 ($1,063,572) 0.01 $148,702 ($24,163,324) 0.03 $842,548 ($30,239,360)
United Therapeutics Corp 0.00 $0 ($1,056,425) 0.00 $0 ($2,070,512) 0.00 $0 ($2,772,042)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($830,904) 0.01 $51,338 ($4,314,734) 0.02 $152,183 ($6,379,782)
Ani Pharmaceuticals Inc 0.00 $0 ($633,051) 0.00 $0 ($8,417,884) 0.00 $0 ($14,365,642)
Kura Oncology, Inc. 0.00 $0 ($514,856) 0.95 $2,351,000 ($2,472,575) 0.72 $2,351,000 ($3,276,415)
BeOne Medicines Ltd. 0.00 $0 ($418,125) 0.00 $0 ($95,227,620) 0.00 $0 ($133,252,162)
Alnylam Pharmaceuticals, Inc. 0.00 $0 ($398,855) 0.00 $0 ($398,855) 0.00 $0 ($24,178,725)
Cue Biopharma, Inc. 0.00 $0 ($389,304) 0.00 $0 ($389,304) 0.26 $99,747 ($389,304)
Verastem, Inc. 0.00 $0 ($373,496) 0.00 $0 ($490,505) 0.00 $0 ($1,023,336)
Xeris Biopharma Holdings, Inc. 0.00 $0 ($344,949) 0.00 $0 ($3,049,066) 0.00 $0 ($5,004,480)
Ptc Therapeutics, Inc. 0.00 $0 ($307,517) 0.00 $0 ($8,524,588) 0.00 $0 ($19,464,674)
Legend Biotech Corp 0.00 $0 ($258,920) 0.00 $0 ($479,616) 0.00 $0 ($566,755)
Royalty Pharma Plc 0.00 $0 ($235,595) 0.00 $0 ($34,571,049) 0.00 $0 ($92,823,522)
Ocular Therapeutix, Inc 0.00 $0 ($234,419) 0.00 $0 ($927,920) 0.14 $461,354 ($3,296,177)
Oramed Pharmaceuticals Inc. 0.00 $0 ($225,530) 0.00 $0 ($556,274) 0.00 $0 ($556,274)
Abeona Therapeutics Inc. 0.00 $0 ($208,431) 0.00 $0 ($2,184,644) 0.00 $0 ($3,567,776)
Adlai Nortye Group Ltd. 0.00 $0 ($163,275) 0.00 $0 ($411,191) 0.00 $0 ($411,191)
Emergent Biosolutions Inc. 0.00 $0 ($145,792) 0.00 $0 ($689,232) 0.00 $0 ($996,135)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($107,898) 0.00 $0 ($924,415) 0.00 $0 ($3,809,849)
Aquestive Therapeutics, Inc. 0.00 $0 ($105,600) 0.00 $0 ($572,870) 0.00 $0 ($2,224,085)
Elanco Animal Health Inc 0.00 $0 ($100,050) 16.72 $1,672,850 ($100,050) 26.09 $2,610,757 ($100,050)
Alkermes Plc. 0.00 $0 ($83,455) 0.00 $0 ($1,008,045) 0.00 $0 ($1,809,477)
BELITE BIO, INC 0.00 $0 ($82,659) 0.00 $0 ($35,994,497) 0.00 $0 ($40,625,543)
Bicycle Therapeutics Plc 0.00 $0 ($64,039) 0.00 $0 ($124,500) 0.00 $0 ($522,733)
Q32 Bio Inc. 0.00 $0 ($45,251) 93.63 $30,000,000 ($320,396) 59.40 $30,000,000 ($505,079)
Stoke Therapeutics, Inc. 0.00 $0 ($44,002) 0.00 $0 ($830,592) 0.00 $0 ($6,395,098)
Rallybio Corp 0.00 $0 ($9,608) 0.00 $0 ($9,608) 0.00 $0 ($13,600)
Rockwell Medical, Inc. 0.00 $0 ($8,420) 0.00 $0 ($8,420) 0.00 $0 ($15,975)
Lyell Immunopharma, Inc. 0.00 $0 ($3,642) 0.00 $0 ($255,242) 0.00 $0 ($607,954)
Karyopharm Therapeutics Inc. 0.00 $0 ($2,097) 0.00 $0 ($38,219) 0.00 $0 ($351,406)
Acrivon Therapeutics, Inc. 0.00 $0 ($1,529) 0.00 $0 ($41,335) 2.77 $114,341 ($41,335)
RedHill Biopharma Ltd. 0.00 $0 ($1,431) 0.00 $0 ($2,844) 0.00 $0 ($4,418)
Xenon Pharmaceuticals Inc. -- $1,681,140 $0 1.40 $1,681,140 ($1,199,867) 0.72 $1,681,140 ($2,346,746)
Xbiotech Inc. -- $711,251 $0 -- $711,251 $0 -- $711,251 $0
FILANA THERAPEUTICS, INC. -- $278,132 $0 -- $356,328 $0 -- $997,077 $0
Anixa Biosciences Inc -- $61,220 $0 -- $475,522 $0 -- $505,922 $0
Lipocine Inc. -- $55,043 $0 -- $82,174 $0 -- $516,774 $0
Dyne Therapeutics, Inc. -- $40,000 $0 0.00 $196,800 ($115,879,195) 0.00 $314,840 ($168,617,119)
Helus Pharma Inc. -- $38,730 $0 -- $9,670,162 $0 -- $9,670,162 $0
Veraxa Biotech AG - Post de-SPAC -- $32,700 $0 -- $115,350 $0 -- $115,350 $0
ELITE PHARMACEUTICALS INC /NV/ -- $25,980 $0 -- $34,590 $0 -- $34,590 $0
Hepion Pharmaceuticals, Inc. -- $10,000 $0 -- $835,000 $0 -- $1,235,000 $0
Phio Pharmaceuticals Corp. -- $5,200 $0 -- $68,950 $0 -- $91,250 $0
Ctt Pharmaceutical Holdings, Inc. -- $653 $0 -- $4,625 $0 -- $16,017 $0
Enliven Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,202,806) 0.00 $0 ($8,312,324)
Bridgebio Pharma, Inc. -- $0 $0 0.00 $0 ($18,227,851) 0.00 $0 ($78,092,222)
Faeth Therapeutics, Inc. -- $0 $0 -- $1,133,317 $0 -- $1,133,317 $0
Eli Lilly & Co -- $0 $0 0.00 $0 ($18,835,095) 0.00 $0 ($19,845,595)
Emmaus Life Sciences, Inc. -- $0 $0 -- $15,026 $0 -- $15,026 $0
Arrowhead Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,414,934) 0.00 $0 ($33,768,522)
Arvinas, Inc. -- $0 $0 0.00 $0 ($518,078) 0.19 $268,070 ($1,421,163)
Amphastar Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($340,633) 0.00 $0 ($460,774)
Aurinia Pharmaceuticals Inc. -- $0 $0 22.80 $12,455,227 ($546,373) 46.02 $25,144,033 ($546,373)
Greenwich Lifesciences, Inc. -- $0 $0 -- $97,003 $0 -- $586,328 $0
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($785,946) 0.00 $0 ($1,352,437)
Precigen, Inc. -- $0 $0 0.01 $24,662 ($4,467,859) 0.00 $24,662 ($41,307,834)
Processa Pharmaceuticals, Inc. -- $0 $0 -- $130,096 $0 -- $208,638 $0
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($1,129,758) 0.00 $0 ($1,548,747)
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($62,181) 0.09 $86,588 ($962,955)
Arcutis Biotherapeutics, Inc. -- $0 $0 0.00 $0 ($1,172,740) 0.00 $0 ($9,422,267)
Regeneron Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,203,012) 0.00 $0 ($2,717,908)
Prothena Corp Public Ltd Co -- $0 $0 0.00 $0 ($135,975) 0.00 $0 ($135,975)
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($366,143) 0.00 $0 ($2,520,753)
Travere Therapeutics, Inc. -- $0 $0 0.00 $0 ($183,952) 0.00 $0 ($9,970,870)
Insmed Inc -- $0 $0 0.00 $0 ($12,921,016) 0.00 $0 ($39,778,676)
Urogen Pharma Ltd. -- $0 $0 0.00 $0 ($3,904,953) 0.00 $0 ($4,300,127)
Keros Therapeutics, Inc. -- $0 $0 0.22 $41,650 ($191,130) 0.14 $75,770 ($522,950)
Tg Therapeutics, Inc. -- $0 $0 0.00 $0 ($274,800) 0.00 $0 ($437,650)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($412,305) 0.00 $0 ($1,083,288)
Olema Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($291,162) 0.00 $0 ($5,277,355)
Entrada Therapeutics, Inc. -- $0 $0 0.01 $29,316 ($2,284,775) 0.01 $29,316 ($4,674,123)
Biomarin Pharmaceutical Inc -- $0 $0 0.00 $0 ($1,340,430) 0.00 $0 ($4,318,214)
Shattuck Labs, Inc. -- $0 $0 0.61 $250,000 ($408,600) 0.61 $250,000 ($408,600)
Bausch Health Companies Inc. -- $0 $0 0.00 $0 ($391,690) 0.00 $0 ($506,730)
Pacira Biosciences, Inc. -- $0 $0 0.00 $0 ($442,790) 0.00 $0 ($1,277,179)
Zai Lab Ltd -- $0 $0 0.08 $33,071 ($433,507) 0.04 $65,804 ($1,550,156)
Uniqure N.V. -- $0 $0 0.00 $0 ($966,917) 0.00 $0 ($2,258,860)
Bolt Biotherapeutics, Inc. -- $0 $0 0.03 $4,442 ($128,281) 0.04 $5,594 ($128,281)
Vertex Pharmaceuticals Inc / Ma -- $0 $0 0.00 $0 ($11,005,690) 0.00 $0 ($65,281,011)
Mannkind Corp -- $0 $0 0.00 $0 ($480,592) 0.00 $0 ($872,588)
Syndax Pharmaceuticals Inc -- $0 $0 0.00 $0 ($152,376) 0.00 $0 ($780,667)
Viridian Therapeutics, Inc.\De -- $0 $0 -- $19,999,990 $0 282.50 $19,999,990 ($70,796)
Nuvectis Pharma, Inc. -- $0 $0 -- $250,000 $0 -- $418,110 $0
Rocket Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($535,661) 0.05 $34,400 ($692,164)
Lifevantage Corp -- $0 $0 0.09 $12,130 ($141,108) 0.42 $195,986 ($471,625)
Cytokinetics Inc -- $0 $0 0.00 $0 ($5,711,391) 0.00 $0 ($13,529,515)
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $0 ($31,707,557) 0.00 $0 ($55,103,501)
Rhythm Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($912,703) 0.00 $0 ($3,129,837)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($914,400) 0.00 $0 ($1,066,655)
Korro Bio, Inc. -- $0 $0 0.00 $0 ($5,698,848) 0.00 $0 ($5,698,848)
GYRE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($82,927) 0.00 $0 ($82,927)
Zoetis Inc. -- $0 $0 -- $886,367 $0 -- $886,367 $0
Nuvalent, Inc. -- $0 $0 0.00 $0 ($261,363) 0.00 $0 ($43,310,793)
Wave Life Sciences, Inc. -- $0 $0 0.00 $0 ($93,002) 57.68 $54,631,065 ($947,139)
Nektar Therapeutics -- $0 $0 0.00 $0 ($2,034,537) 0.00 $0 ($2,433,286)
Abbott Laboratories -- $0 $0 0.27 $173,640 ($645,463) 3.30 $4,402,775 ($1,333,826)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($33,550) 0.00 $0 ($33,550)
Ardelyx, Inc. -- $0 $0 0.00 $0 ($1,027,139) 0.98 $1,946,331 ($1,988,178)
Bristol Myers Squibb Co -- $0 $0 0.00 $0 ($437,248) 0.00 $0 ($2,287,264)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($162,542) 0.00 $0 ($4,285,614)
Abcellera Biologics Inc. -- $0 $0 -- $1,641,080 $0 -- $1,965,232 $0
Ligand Pharmaceuticals Inc -- $0 $0 0.00 $0 ($4,174,209) 0.00 $0 ($5,270,564)
Altimmune, Inc. -- $0 $0 -- $44,250 $0 -- $370,038 $0
Theravance Biopharma, Inc. -- $0 $0 0.00 $0 ($444,961) 0.00 $0 ($2,860,368)
Ironwood Pharmaceuticals Inc -- $0 $0 0.00 $0 ($658,523) 0.00 $0 ($22,497,443)
Imunon, Inc. -- $0 $0 0.00 $0 ($38,153) 0.00 $0 ($38,153)
Xencor Inc -- $0 $0 0.00 $0 ($379,135) 0.00 $0 ($950,090)
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 0.33 $126,255 ($381,156) 0.20 $126,255 ($628,664)
Evolus, Inc. -- $0 $0 0.00 $0 ($950,019) 0.00 $0 ($1,121,292)
CRESCENT BIOPHARMA, INC. -- $0 $0 8.19 $12,375,025 ($1,511,627) 20.25 $30,612,625 ($1,511,627)
Cryoport, Inc. -- $0 $0 0.00 $0 ($6,660,257) 0.00 $0 ($6,901,051)
Chemomab Therapeutics Ltd. -- $0 $0 3.11 $20,246 ($6,516) 3.11 $20,246 ($6,516)
Immuneering Corp -- $0 $0 -- $35,993 $0 -- $270,336 $0
Viatris Inc -- $0 $0 0.00 $0 ($809,784) 0.00 $0 ($1,093,323)
Johnson & Johnson -- $0 $0 0.00 $0 ($12,515,010) 0.01 $257,688 ($34,962,666)
Arcus Biosciences, Inc. -- $0 $0 0.00 $0 ($3,174,409) 0.00 $0 ($12,052,095)
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($240,364) 0.00 $0 ($575,586)
Damora Therapeutics, Inc. -- $0 $0 -- $252,875 $0 -- $252,875 $0
Oric Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,600) 0.00 $0 ($84,031)
Tonix Pharmaceuticals Holding Corp. -- $0 $0 -- $172,308 $0 -- $458,758 $0
Assembly Biosciences, Inc. -- $0 $0 0.00 $0 ($674) 0.00 $0 ($14,687)
Oruka Therapeutics, Inc. -- $0 $0 0.00 $0 ($3,268,113) 0.00 $0 ($3,410,887)
Alzamend Neuro, Inc. -- $0 $0 0.00 $0 ($3,116) 23.63 $330,827 ($14,000)
CalciMedica, Inc. -- $0 $0 -- $199,999 $0 -- $199,999 $0
Relmada Therapeutics, Inc. -- $0 $0 -- $1,671,990 $0 -- $4,030,050 $0
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($65,614) 0.00 $0 ($599,654)
Ionis Pharmaceuticals Inc -- $0 $0 0.37 $1,058,700 ($2,860,152) 0.05 $1,058,700 ($23,254,088)
Nuvation Bio Inc. -- $0 $0 -- $118,250 $0 -- $118,250 $0
Annexon, Inc. -- $0 $0 -- $3,465,088 $0 39.58 $12,406,197 ($313,428)
Schrodinger, Inc. -- $0 $0 0.00 $0 ($13,647) 0.00 $0 ($317,601)
Avalo Therapeutics, Inc. -- $0 $0 0.00 $0 ($347,063) 0.00 $0 ($617,656)
KYNTRA BIO, INC. -- $0 $0 -- $19,852 $0 -- $53,602 $0
Nkarta, Inc. -- $0 $0 0.00 $0 ($4,813) 0.00 $0 ($70,422)
Kiniksa Pharmaceuticals International, plc -- $0 $0 0.00 $0 ($299,092) 0.00 $0 ($1,190,607)
Zomedica Corp. -- $0 $0 -- $146,903 $0 -- $193,929 $0
Neurogene Inc. -- $0 $0 0.00 $0 ($640,005) 0.00 $0 ($1,133,592)
Phibro Animal Health Corp -- $0 $0 0.18 $317,700 ($1,760,246) 0.02 $317,700 ($18,034,090)
Lite Strategy, Inc. -- $0 $0 -- $21,388 $0 -- $141,864 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $49,997 $0 68.30 $49,997 ($732)
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($120,444) 0.00 $0 ($424,424)
Mirum Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,061,295) 2.75 $8,999,984 ($3,273,974)
Macrogenics Inc -- $0 $0 0.00 $0 ($129,086) 0.00 $0 ($129,086)
Veru Inc. -- $0 $0 -- $4,842 $0 -- $4,842 $0
Alx Oncology Holdings Inc -- $0 $0 0.00 $0 ($8,274) 117.40 $4,999,999 ($42,588)
Amneal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($7,667,124) 0.00 $0 ($8,253,124)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,953) 0.00 $0 ($1,232,151)
Eton Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($9,913,490) 0.00 $0 ($9,913,490)
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,867) 0.00 $0 ($5,630)
Protagenic Therapeutics, Inc.\New -- $0 $0 -- $30,717 $0 -- $30,717 $0
Werewolf Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,062,008) 0.00 $0 ($3,102,601)
Corvus Pharmaceuticals, Inc. -- $0 $0 -- $333,689 $0 -- $333,689 $0
Cocrystal Pharma, Inc. -- $0 $0 -- $80,406 $0 -- $300,212 $0
Pfizer Inc -- $0 $0 21.98 $2,960,110 ($134,661) 21.98 $2,960,110 ($134,661)
Merck & Co., Inc. -- $0 $0 0.00 $0 ($10,046,142) 0.00 $0 ($29,406,103)
Summit Therapeutics Inc. -- $0 $0 -- $103,616,650 $0 -- $103,616,650 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($495,047) 0.00 $0 ($619,095)
CervoMed Inc. -- $0 $0 -- $3,000,000 $0 -- $3,737,723 $0
Immunome Inc. -- $0 $0 0.01 $103,500 ($9,944,909) 0.11 $2,101,730 ($19,814,853)
Verrica Pharmaceuticals Inc. -- $0 $0 -- $210,890 $0 -- $18,183,588 $0
Equillium, Inc. -- $0 $0 0.00 $0 ($723,830) 0.00 $0 ($787,440)
Viking Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,267,665) 0.01 $149,912 ($17,758,161)
Janux Therapeutics, Inc. -- $0 $0 0.00 $0 ($85,822) 0.00 $0 ($347,145)
Larimar Therapeutics, Inc. -- $0 $0 -- $166,890 $0 -- $25,716,890 $0
Hcw Biologics Inc. -- $0 $0 -- $529,993 $0 -- $529,993 $0
Climb Bio, Inc. -- $0 $0 0.00 $0 ($1,366,820) 0.35 $779,626 ($2,246,202)
Organon & Co. -- $0 $0 0.00 $0 ($553,382) 0.91 $501,755 ($553,382)
Annovis Bio, Inc. -- $0 $0 -- $142,779 $0 -- $2,256,875 $0
Tyra Biosciences, Inc. -- $0 $0 -- $19,982 $0 0.00 $19,982 ($10,061,326)
CYPHERPUNK TECHNOLOGIES INC. -- $0 $0 0.00 $0 ($888,900) 0.00 $0 ($6,000,991)
Axsome Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,161,126) 0.00 $0 ($8,188,876)
Cns Pharmaceuticals, Inc. -- $0 $0 -- $44,002 $0 -- $44,002 $0
Dermata Therapeutics, Inc. -- $0 $0 0.00 $0 ($13) 97.01 $1,270 ($13)
Biovie Inc. -- $0 $0 -- $49,118 $0 -- $49,118 $0
Atea Pharmaceuticals, Inc. -- $0 $0 -- $25,446 $0 -- $25,446 $0
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($63,352) 0.00 $0 ($552,042)
Madrigal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($10,461,835) 0.00 $0 ($17,158,081)
Aldeyra Therapeutics, Inc. -- $0 $0 -- $418,450 $0 -- $523,550 $0
Oncotelic Therapeutics, Inc. -- $0 $0 -- $37,832 $0 -- $37,832 $0
Natures Sunshine Products Inc -- $0 $0 0.00 $0 ($742,411) 0.00 $0 ($2,094,604)
Tenax Therapeutics, Inc. -- $0 $0 -- $132,828 $0 -- $337,296 $0
Rein Therapeutics, Inc. -- $0 $0 -- $74,561 $0 -- $74,561 $0
Lantern Pharma Inc. -- $0 $0 -- $200,001 $0 -- $200,001 $0
Skye Bioscience, Inc. -- $0 $0 0.00 $0 ($444,602) 0.00 $0 ($444,602)
Tango Therapeutics, Inc. -- $0 $0 0.00 $0 ($198,613) 0.00 $0 ($1,923,711)
MoonLake Immunotherapeutics -- $0 $0 0.00 $0 ($9,613,406) 0.00 $0 ($83,026,619)
Maravai Lifesciences Holdings, Inc. -- $0 $0 0.00 $0 ($254,000) 7.40 $1,880,244 ($254,000)
Ensysce Biosciences, Inc. -- $0 $0 -- $198,000 $0 -- $444,169 $0
Rigel Pharmaceuticals Inc -- $0 $0 0.00 $0 ($160,425) 0.00 $0 ($160,425)
An2 Therapeutics, Inc. -- $0 $0 0.03 $11,602 ($344,181) 0.03 $11,602 ($398,298)
Promis Neurosciences Inc. -- $0 $0 -- $30,324 $0 -- $241,869 $0
HARROW, INC. -- $0 $0 -- $468,720 $0 -- $468,720 $0
Rani Therapeutics Holdings, Inc. -- $0 $0 -- $50,033 $0 166.18 $50,033 ($301)
Pepgen Inc. -- $0 $0 0.00 $0 ($1,739) 0.00 $0 ($59,312)
Maia Biotechnology, Inc. -- $0 $0 -- $556,093 $0 -- $985,885 $0
ASTRAZENECA PLC -- $0 $0 0.00 $3,211 ($2,209,482) 0.00 $3,211 ($2,209,482)
TAKEDA PHARMACEUTICAL CO LTD -- $0 $0 0.00 $0 ($13,088,587) 0.00 $0 ($13,088,587)
Ascendis Pharma A/S -- $0 $0 0.17 $777,066 ($4,703,356) 0.17 $777,066 ($4,703,356)
Prenetics Global Ltd -- $0 $0 -- $497,700 $0 -- $497,700 $0
NovaBridge Biosciences -- $0 $0 0.00 $0 ($122,488) 4.71 $577,300 ($122,488)
AC Immune SA -- $0 $0 0.00 $0 ($27,935) 0.00 $0 ($59,360)
KAMADA LTD -- $0 $0 0.00 $0 ($1,650,459) 0.00 $0 ($1,650,459)
Pharvaris N.V. -- $0 $0 0.00 $0 ($11,956,228) 0.00 $0 ($12,882,450)
Tiziana Life Sciences Ltd -- $0 $0 -- $1,044,492 $0 -- $1,044,492 $0
ProQR Therapeutics N.V. -- $0 $0 -- $1,342,385 $0 -- $1,342,385 $0
Adagene Inc. -- $0 $0 -- $162,244 $0 -- $162,244 $0
Connect Biopharma Holdings Ltd -- $0 $0 -- $371,610 $0 -- $4,373,610 $0
Grace Therapeutics, Inc. -- $0 $0 -- $214,000 $0 -- $214,000 $0
Serina Therapeutics, Inc. -- $0 $0 -- $76,881 $0 -- $76,881 $0
ALTERITY THERAPEUTICS LTD -- $0 $0 -- $23,810 $0 -- $23,810 $0
NeuroSense Therapeutics Ltd. -- $0 $0 -- $400,000 $0 -- $400,000 $0
Quoin Pharmaceuticals Ltd. -- $0 $0 -- $279,966 $0 -- $279,966 $0
SciSparc Ltd. -- $0 $0 0.00 $0 ($4,620) 0.00 $0 ($4,620)
International Stem Cell CORP -- $0 $0 0.00 $0 ($10,497) 0.00 $0 ($10,497)
NewAmsterdam Pharma Co N.V. -- $0 $0 5.59 $226,500 ($40,512) 0.07 $226,500 ($3,461,426)
Cadrenal Therapeutics, Inc. -- $0 $0 0.00 $0 ($388,290) 0.00 $0 ($457,523)
GENELUX CORP -- $0 $0 0.00 $0 ($237,311) 0.00 $0 ($368,042)
BullFrog AI Holdings, Inc. -- $0 $0 -- $71,342 $0 -- $71,342 $0
CytoMed Therapeutics Ltd -- $0 $0 -- $428,778 $0 -- $428,778 $0
Apollomics Inc. -- $0 $0 -- $8,250,009 $0 -- $8,250,009 $0
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $10,131 $0 -- $30,095 $0
Indivior Pharmaceuticals, Inc. -- $0 $0 0.04 $107,955 ($2,829,211) 0.11 $311,563 ($2,829,211)
Sagimet Biosciences Inc. -- $0 $0 0.00 $0 ($719,429) 0.00 $0 ($1,114,872)
NEONC TECHNOLOGIES HOLDINGS, INC. -- $0 $0 -50.65 $851,445 $16,809 -87.95 $1,478,331 $16,809
Contineum Therapeutics, Inc. -- $0 $0 0.00 $0 ($109,556) 0.00 $0 ($385,013)
ALUMIS INC. -- $0 $0 24.60 $9,699,359 ($394,311) 99.91 $39,396,484 ($394,311)
Zenas Biopharma, Inc. -- $0 $0 -- $1,629,500 $0 -- $11,418,466 $0
Mbx Biosciences, Inc. -- $0 $0 0.00 $0 ($49,089) 10.71 $525,663 ($49,089)
Camp4 Therapeutics Corp -- $0 $0 0.04 $99,051 ($2,504,037) 0.04 $99,051 ($2,504,037)
Upstream Bio, Inc. -- $0 $0 0.00 $0 ($58,226) 0.00 $0 ($104,796)
Telix Pharmaceuticals Ltd -- $0 $0 -- $517,176 $0 -- $1,016,736 $0
Septerna, Inc. -- $0 $0 0.00 $0 ($63,452,500) 0.00 $0 ($63,515,723)
Sionna Therapeutics, Inc. -- $0 $0 0.00 $0 ($66,822,500) 0.00 $0 ($139,885,152)
Aardvark Therapeutics, Inc. -- $0 $0 0.00 $0 ($394,957) 0.37 $144,595 ($394,957)
Nasus Pharma Ltd -- $0 $0 -- $20,305 $0 -- $61,809 $0
Evommune, Inc. -- $0 $0 0.22 $146,260 ($673,747) 0.24 $163,610 ($673,747)
Veradermics, Inc -- $0 $0 0.00 $0 ($10,711,700) 1.45 $15,542,467 ($10,711,700)
Polaryx Therapeutics, Inc. -- $0 $0 -- $360,004 $0 -- $367,994 $0
Generate Biomedicines, Inc. -- $0 $0 0.00 $0 ($16,002) 18.80 $300,800 ($16,002)
Seaport Therapeutics, Inc. -- $0 $0 -- $235,768 $0 -- $235,768 $0
Parabilis Medicines, Inc. -- $0 $0 -- $7,643,080 $0 -- $7,643,080 $0
Kardigan, Inc. -- $0 $0 -- $40,000,000 $0 -- $40,000,000 $0
Apnimed, Inc. -- $0 $0 -- $200,000 $0 -- $200,000 $0
Braveheart Bio, Inc. -- $0 $0 -- $4,594,950 $0 -- $4,594,950 $0
Blossomhill Therapeutics, Inc. -- $0 $0 -- $107,200 $0 -- $107,200 $0
Veraxa Biotech Ag -- $0 $0 -- $10,060 $0 -- $10,060 $0
Amicus Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,471,085)
Apellis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,785,604)
Zentalis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($134,670)
Harmony Biosciences Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,011,950)
Cartesian Therapeutics, Inc. -- $0 $0 -- $0 $0 0.80 $205,797 ($258,671)
Tempest Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $1,000,002 $0
Galectin Therapeutics Inc -- $0 $0 -- $0 $0 -- $25,546 $0
Enanta Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($183,167)
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $196,731 $0
Soleno Therapeutics Inc -- $0 $0 -- $0 $0 0.00 $0 ($429,344)
Clene Inc. -- $0 $0 -- $0 $0 -- $216,664 $0
Abbvie Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,597,068)
Vera Therapeutics, Inc. -- $0 $0 -- $0 $0 0.10 $249,985 ($2,524,590)
Phathom Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($7,079)
Aprea Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $60,907 $0
Vanda Pharmaceuticals Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,824,768)
Perrigo Co Plc -- $0 $0 -- $0 $0 -- $106,350 $0
Decoy Therapeutics Inc. -- $0 $0 -- $0 $0 1142.93 $19,740 ($17)
Edesa Biotech, Inc. -- $0 $0 -- $0 $0 -- $233,054 $0
Organogenesis Holdings Inc. -- $0 $0 -- $0 $0 0.02 $40,093 ($2,619,180)
Ibio, Inc. -- $0 $0 -- $0 $0 -- $98,106 $0
Iterum Therapeutics Plc -- $0 $0 -- $0 $0 -- $2,191 $0
Cingulate Inc. -- $0 $0 -- $0 $0 -- $656,964 $0
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,816)
XOMA Royalty Corp -- $0 $0 -- $0 $0 -- $2,505,000 $0
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($198)
Synlogic, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($284)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,806)
Protagonist Therapeutics, Inc -- $0 $0 -- $0 $0 0.00 $0 ($4,747,968)
Ideaya Biosciences, Inc. -- $0 $0 -- $0 $0 -- $1,647,890 $0
Anaptysbio, Inc -- $0 $0 -- $0 $0 0.00 $0 ($2,440,993)
Monopar Therapeutics -- $0 $0 -- $0 $0 0.31 $104,925 ($343,889)
Galera Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,407)
Savara Inc -- $0 $0 -- $0 $0 0.00 $0 ($121,220)
Sarepta Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($417,410)
Mustang Bio, Inc. -- $0 $0 -- $0 $0 0.98 $238 ($241)
Lexicon Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $2,722,625 $0
Avidity Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,226,448)
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($163,620)
Edgewise Therapeutics, Inc. -- $0 $0 -- $0 $0 0.39 $199,403 ($506,735)
Genprex, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($22)
Prelude Therapeutics Inc -- $0 $0 -- $0 $0 -- $24,999,997 $0
Supernus Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,034,850)
Cogent Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($139,578,705)
Therapeuticsmd, Inc. -- $0 $0 -- $0 $0 -- $14,031 $0
Silo Pharma, Inc. -- $0 $0 -- $0 $0 -- $7,657 $0
Cormedix Inc. -- $0 $0 -- $0 $0 0.00 $0 ($886,600)
Aditxt, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5)
Opko Health, Inc. -- $0 $0 -- $0 $0 -- $3,202,941 $0
Centessa Pharmaceuticals Plc -- $0 $0 -- $0 $0 0.00 $0 ($3,220,338)
Palatin Technologies Inc -- $0 $0 -- $0 $0 0.00 $0 ($9,461)
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($29,286)
Rezolute, Inc. -- $0 $0 -- $0 $0 -- $284,397 $0
Catalyst Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -0.00 $0 $908,000
Xilio Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $43,950 $0
Sellas Life Sciences Group, Inc. -- $0 $0 -- $0 $0 -- $100,806 $0
Immix Biopharma, Inc. -- $0 $0 -- $0 $0 -- $4,976 $0
STANDARD BIOTOOLS INC. -- $0 $0 -- $0 $0 -- $14,436,518 $0
TALPHERA, INC. -- $0 $0 -- $0 $0 -- $304,001 $0
Milestone Pharmaceuticals Inc. -- $0 $0 -- $0 $0 0.00 $0 ($180,365)
Perspective Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $42,241 $0
Aptevo Therapeutics Inc. -- $0 $0 -- $0 $0 -- $20,134 $0
Terns Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($94,245)
Whitehawk Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,459,560)
Benitec Biopharma Inc. -- $0 $0 -- $0 $0 -- $22,442,099 $0
Pasithea Therapeutics Corp. -- $0 $0 -- $0 $0 -- $149,999 $0
Biohaven Ltd. -- $0 $0 -- $0 $0 -- $33,144,763 $0
ONCOLYTICS BIOTECH INC -- $0 $0 -- $0 $0 -- $362,615 $0
BIOXYTRAN, INC -- $0 $0 -- $0 $0 -- $126,000 $0
Valion Bio, Inc. -- $0 $0 -- $0 $0 -- $28,408 $0
NewcelX Ltd. -- $0 $0 -- $0 $0 -- $374,998 $0
Mural Oncology plc -- $0 $0 -- $0 $0 0.00 $0 ($25,414)
FibroBiologics, Inc. -- $0 $0 -- $0 $0 -- $120,560 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,624,000)
IMPACT BIOMEDICAL INC. -- $0 $0 -- $0 $0 0.00 $0 ($57,835)
Bicara Therapeutics Inc. -- $0 $0 -- $0 $0 66.68 $4,800,000 ($71,981)
Bioage Labs, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,223,036)
Turn Therapeutics Inc. -- $0 $0 -- $0 $0 -- $117,747 $0
Ataibeckley Inc. -- $0 $0 -- $0 $0 0.00 $0 ($154,377)