Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 4/30/2025 10:07:34 PM
1 Month
Buy/Sell Ratio 1.59
61%
39%
Buy Sell
$32.29 M ($20.30) M
42 Insiders 76 Insiders
75 Transactions 98 Transactions
3/30/2025 to 4/30/2025
3 Month
Buy/Sell Ratio 0.36
26%
74%
Buy Sell
$158.03 M ($435.36) M
125 Insiders 395 Insiders
317 Transactions 669 Transactions
1/30/2025 to 4/30/2025
6 Month
Buy/Sell Ratio 0.38
27%
73%
Buy Sell
$347.73 M ($916.56) M
248 Insiders 581 Insiders
740 Transactions 1293 Transactions
10/30/2024 to 4/30/2025
12 Month
Buy/Sell Ratio 0.31
23%
77%
Buy Sell
$581.82 M ($1,862.95) M
384 Insiders 826 Insiders
1217 Transactions 2403 Transactions
4/30/2024 to 4/30/2025

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Janux Therapeutics, Inc.
$79,042,965 4
Zymeworks Inc.
$57,400,468 34
89Bio, Inc.
$49,999,994 1
Climb Bio, Inc.
$49,952,817 1
ALUMIS INC.
$25,000,000 1
Aurinia Pharmaceuticals Inc.
$23,535,126 6
Bicycle Therapeutics Plc
$21,230,385 2
Precigen, Inc.
$19,999,999 1
Tyra Biosciences, Inc.
$19,836,066 1
Akero Therapeutics, Inc.
$18,387,921 4

Most Insider Selling

12 months
Name Value Transactions
Beigene, Ltd.
($384,735,063) 2
Nuvalent, Inc.
($110,000,000) 1
MoonLake Immunotherapeutics
($100,003,200) 1
Nuvalent, Inc.
($97,750,000) 1
Dyne Therapeutics, Inc.
($97,727,621) 43
Regeneron Pharmaceuticals, Inc.
($97,430,272) 2
Roivant Sciences Ltd.
($51,232,227) 5
Janux Therapeutics, Inc.
($37,081,025) 1
Abbvie Inc.
($32,666,600) 3
Bridgebio Pharma, Inc.
($30,243,415) 6

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Avadel Pharmaceuticals Plc 6 7
Zomedica Corp. 5 9
Elanco Animal Health Inc 5 6
Immunome Inc. 4 13
Biohaven Ltd. 4 13
Maia Biotechnology, Inc. 4 10
Nuvation Bio Inc. 4 9
Rezolute, Inc. 4 8
CalciMedica, Inc. 4 8
Relmada Therapeutics, Inc. 4 7

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Apellis Pharmaceuticals, Inc. 12 32
Vertex Pharmaceuticals Inc / Ma 11 42
Blueprint Medicines Corp 11 27
Xencor Inc 11 12
Aurinia Pharmaceuticals Inc. 10 15
Puma Biotechnology, Inc. 10 12
Ptc Therapeutics, Inc. 9 34
Ani Pharmaceuticals Inc 9 28
Nuvalent, Inc. 9 22
Arrowhead Pharmaceuticals, Inc. 9 19

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Rocket Pharmaceuticals, Inc. 4.48 $200,765 ($44,786) 0.26 $200,765 ($765,889) 0.16 $200,765 ($1,276,996)
IMPACT BIOMEDICAL INC. 0.00 $0 ($4,209,761) 0.00 $5,173 ($4,209,761) 0.00 $5,173 ($4,209,761)
Corcept Therapeutics Inc 0.00 $0 ($3,365,010) 0.00 $0 ($3,889,850) 0.00 $0 ($4,000,586)
Bridgebio Pharma, Inc. 0.00 $0 ($2,558,025) 0.00 $0 ($30,336,552) 0.00 $0 ($30,412,344)
Arrowhead Pharmaceuticals, Inc. 0.00 $0 ($1,533,337) 0.00 $0 ($6,179,759) 0.00 $0 ($6,459,174)
Cytokinetics Inc 0.00 $0 ($1,120,905) 0.00 $0 ($7,168,611) 0.00 $0 ($10,903,487)
Rhythm Pharmaceuticals, Inc. 0.00 $0 ($1,082,497) 0.00 $0 ($1,509,174) 0.00 $0 ($1,509,174)
Akero Therapeutics, Inc. 0.00 $0 ($1,056,780) 1.90 $18,387,921 ($9,657,822) 1.66 $18,387,921 ($11,059,495)
Centessa Pharmaceuticals Plc 0.00 $0 ($841,433) 0.00 $0 ($5,125,298) 0.00 $0 ($8,383,035)
Amneal Pharmaceuticals, Inc. 0.00 $0 ($664,000) 0.00 $0 ($6,999,156) 0.00 $0 ($8,521,644)
Liquidia Corp 0.00 $0 ($521,665) 0.00 $0 ($1,463,495) 1.53 $2,999,994 ($1,954,411)
Kiniksa Pharmaceuticals International, plc 0.00 $0 ($370,475) 0.00 $0 ($370,475) 0.00 $0 ($370,475)
Mineralys Therapeutics, Inc. 0.00 $0 ($316,487) 50.13 $29,099,992 ($580,433) 2.59 $29,099,992 ($11,230,784)
Arcutis Biotherapeutics, Inc. 0.00 $0 ($302,934) 0.01 $34,024 ($2,616,225) 0.01 $47,560 ($3,648,456)
Enliven Therapeutics, Inc. 0.00 $0 ($282,731) 0.00 $0 ($1,089,768) 0.00 $0 ($53,404,572)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($261,779) 0.07 $37,005 ($494,470) 0.68 $474,199 ($697,367)
Harmony Biosciences Holdings, Inc. 0.00 $0 ($227,386) 0.00 $0 ($227,386) 0.00 $0 ($1,501,932)
Blueprint Medicines Corp 0.00 $0 ($216,461) 0.00 $0 ($8,164,050) 0.00 $0 ($10,254,277)
Jazz Pharmaceuticals Plc 0.00 $0 ($185,625) 0.00 $0 ($4,329,661) 0.00 $0 ($5,048,352)
Ptc Therapeutics, Inc. 0.00 $0 ($178,770) 0.00 $0 ($3,529,191) 0.00 $0 ($3,612,135)
Unity Biotechnology, Inc. 0.00 $0 ($140,611) 0.00 $0 ($145,942) 0.00 $0 ($150,511)
Abeona Therapeutics Inc. 0.00 $0 ($119,500) 0.00 $0 ($161,420) 0.13 $51,799 ($394,637)
Checkpoint Therapeutics, Inc. 0.00 $0 ($110,868) 0.00 $0 ($4,598,055) 0.00 $0 ($4,675,363)
89Bio, Inc. 0.00 $0 ($91,208) 309.83 $50,302,794 ($162,357) 129.20 $50,302,794 ($389,352)
Bicycle Therapeutics Plc 0.00 $0 ($84,714) 33.55 $21,230,385 ($632,893) 23.05 $21,230,385 ($920,949)
Rapport Therapeutics, Inc. 0.00 $0 ($81,310) 0.94 $162,238 ($173,516) 2.94 $510,541 ($173,516)
Protagonist Therapeutics, Inc 0.00 $0 ($80,776) 0.00 $0 ($580,490) 0.00 $0 ($1,812,140)
BullFrog AI Holdings, Inc. 0.00 $0 ($74,094) 0.00 $0 ($74,094) 0.00 $0 ($287,295)
Theravance Biopharma, Inc. 0.00 $0 ($36,000) 0.00 $0 ($108,000) 0.00 $0 ($144,000)
Xencor Inc 0.00 $0 ($30,233) 0.00 $0 ($543,088) 0.00 $0 ($955,213)
Ani Pharmaceuticals Inc 0.00 $0 ($27,584) 0.00 $0 ($1,223,525) 0.00 $0 ($16,439,117)
Phathom Pharmaceuticals, Inc. 0.00 $0 ($16,740) 0.87 $224,532 ($257,224) 0.27 $224,532 ($832,371)
Assembly Biosciences, Inc. 0.00 $0 ($14,664) 3.26 $49,998 ($15,315) 0.57 $49,998 ($88,433)
Amphastar Pharmaceuticals, Inc. 0.00 $0 ($14,190) 0.00 $0 ($42,177) 0.00 $0 ($495,126)
OnKure Therapeutics, Inc. 0.00 $0 ($11,748) 0.00 $0 ($11,748) 0.00 $0 ($11,748)
Rockwell Medical, Inc. 0.00 $0 ($11,552) 0.00 $0 ($88,428) 0.00 $0 ($100,088)
Karyopharm Therapeutics Inc. 0.00 $0 ($3,502) 0.00 $0 ($180,608) 0.00 $0 ($1,881,698)
Terns Pharmaceuticals, Inc. 0.00 $0 ($2,366) 0.58 $124,571 ($213,457) 3.56 $5,167,110 ($1,450,317)
Ventyx Biosciences, Inc. 0.00 $0 ($2,019) 24.31 $1,260,462 ($51,860) 24.31 $1,260,462 ($51,860)
Travere Therapeutics, Inc. 0.00 $0 ($631) 0.00 $0 ($2,449,770) 0.00 $0 ($2,887,138)
Synlogic, Inc. 0.00 $0 ($173) 0.00 $0 ($2,975) 0.00 $0 ($3,086)
Esperion Therapeutics, Inc. 0.00 $0 ($113) 0.00 $0 ($73,775) 0.00 $0 ($125,006)
Edgewise Therapeutics, Inc. -- $20,000,000 $0 -- $20,000,000 $0 98.72 $20,000,000 ($202,603)
Zymeworks Inc. -- $6,577,701 $0 -- $57,400,468 $0 -- $57,400,468 $0
Cartesian Therapeutics, Inc. -- $1,522,517 $0 19.01 $11,598,573 ($610,064) 26.37 $16,089,335 ($610,064)
Nuvation Bio Inc. -- $987,205 $0 6.06 $987,205 ($162,883) 24.71 $4,025,027 ($162,883)
XOMA Royalty Corp -- $599,344 $0 -- $709,728 $0 -- $709,728 $0
Opko Health, Inc. -- $519,212 $0 -- $4,296,381 $0 -- $4,634,513 $0
Savara Inc -- $416,250 $0 2.62 $762,922 ($290,675) 2.62 $762,922 ($290,675)
ALUMIS INC. -- $230,277 $0 -- $230,277 $0 -- $25,230,277 $0
Benitec Biopharma Inc. -- $211,736 $0 -- $13,258,726 $0 -- $13,258,726 $0
Bristol Myers Squibb Co -- $202,215 $0 13.16 $512,340 ($38,930) 13.16 $512,340 ($38,930)
Greenwich Lifesciences, Inc. -- $164,835 $0 -- $379,229 $0 -- $3,067,346 $0
TALPHERA, INC. -- $125,000 $0 1109.04 $131,849 ($119) 1306.65 $155,341 ($119)
Renovorx, Inc. -- $119,390 $0 -- $119,390 $0 -- $119,390 $0
PALVELLA THERAPEUTICS, INC. -- $100,797 $0 -- $152,517 $0 -- $152,517 $0
Pepgen Inc. -- $61,275 $0 12.33 $61,275 ($4,971) 0.44 $61,275 ($139,071)
Accustem Sciences Inc. -- $58,876 $0 -- $141,676 $0 -- $141,676 $0
Mbx Biosciences, Inc. -- $45,312 $0 -- $4,621,323 $0 -- $4,621,323 $0
Geovax Labs, Inc. -- $33,883 $0 -- $33,883 $0 -- $49,483 $0
Viking Therapeutics, Inc. -- $29,943 $0 0.00 $29,943 ($12,781,795) 0.00 $29,943 ($21,404,523)
Zentalis Pharmaceuticals, Inc. -- $29,373 $0 3.86 $252,786 ($65,472) 1.11 $252,786 ($227,894)
Lyell Immunopharma, Inc. -- $19,958 $0 -- $447,931 $0 -- $447,931 $0
Rezolute, Inc. -- $19,733 $0 -- $243,733 $0 -- $5,505,237 $0
Aprea Therapeutics, Inc. -- $10,110 $0 -- $10,110 $0 5.95 $176,052 ($29,583)
Therapeuticsmd, Inc. -- $2,809 $0 -- $2,809 $0 -- $11,946 $0
Cumberland Pharmaceuticals Inc -- $279 $0 -- $31,965 $0 -- $45,082 $0
Eli Lilly & Co -- $0 $0 0.00 $0 ($5,857,347) 0.00 $0 ($12,965,995)
Arvinas, Inc. -- $0 $0 0.00 $0 ($845,974) 0.00 $0 ($845,974)
Apellis Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,084,956) 0.00 $0 ($5,906,059)
Aurinia Pharmaceuticals Inc. -- $0 $0 3.96 $23,535,126 ($5,946,646) 3.81 $23,535,126 ($6,169,587)
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($170,471) 0.00 $0 ($1,194,511)
Processa Pharmaceuticals, Inc. -- $0 $0 -- $9,889 $0 -- $9,889 $0
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($195,840) 0.00 $0 ($833,729)
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($687,218) 0.00 $0 ($746,256)
Avid Bioservices, Inc. -- $0 $0 0.00 $0 ($2,785,375) 0.00 $0 ($2,785,375)
KALA BIO, Inc. -- $0 $0 0.00 $0 ($72,531) 0.00 $0 ($319,267)
Day One Biopharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,043,859) 0.00 $0 ($4,961,866)
Verastem, Inc. -- $0 $0 0.00 $0 ($69,690) 0.00 $0 ($88,273)
Y-Mabs Therapeutics, Inc. -- $0 $0 0.00 $0 ($76,905) 0.00 $0 ($2,660,282)
Stoke Therapeutics, Inc. -- $0 $0 0.00 $0 ($949,284) 0.00 $0 ($1,635,592)
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,725,372) 0.00 $0 ($2,988,101)
United Therapeutics Corp -- $0 $0 0.00 $0 ($1,096,991) 0.00 $0 ($1,683,958)
Syros Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($122,320) 1.07 $321,920 ($300,686)
Insmed Inc -- $0 $0 0.00 $0 ($32,311,701) 0.00 $0 ($35,007,434)
Anixa Biosciences Inc -- $0 $0 -- $186,041 $0 -- $445,192 $0
Tg Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,026,057) 0.00 $0 ($2,458,946)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($89,673) 0.00 $0 ($869,167)
2Seventy Bio, Inc. -- $0 $0 0.00 $0 ($446,174) 0.00 $0 ($496,634)
Catalent, Inc. -- $0 $0 0.00 $0 ($167,160) 0.00 $0 ($1,550,163)
Olema Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($11,396,670) 0.00 $0 ($29,512,042)
Galectin Therapeutics Inc -- $0 $0 -- $34,883 $0 -- $81,570 $0
Enanta Pharmaceuticals Inc -- $0 $0 2.02 $256,050 ($126,993) 1.18 $256,050 ($216,583)
Clearside Biomedical, Inc. -- $0 $0 -- $50,300 $0 -- $85,445 $0
Entrada Therapeutics, Inc. -- $0 $0 0.00 $0 ($761,236) 0.32 $427,978 ($1,348,637)
Biomarin Pharmaceutical Inc -- $0 $0 0.00 $0 ($1,036,200) 0.00 $0 ($1,515,010)
LIFECORE BIOMEDICAL, INC. \DE\ -- $0 $0 -- $97,580 $0 -- $5,473,959 $0
Tharimmune, Inc. -- $0 $0 -- $19,848 $0 -- $34,719 $0
Shattuck Labs, Inc. -- $0 $0 -- $0 $0 -- $126,999 $0
Bausch Health Companies Inc. -- $0 $0 0.00 $0 ($3,674) 0.00 $0 ($86,702)
Pacira Biosciences, Inc. -- $0 $0 0.00 $0 ($26,054) 0.33 $215,684 ($653,601)
Repare Therapeutics Inc. -- $0 $0 0.00 $0 ($42,488) 0.00 $0 ($42,488)
Zai Lab Ltd -- $0 $0 0.00 $0 ($1,177,266) 0.04 $64,200 ($1,803,365)
Regulus Therapeutics Inc. -- $0 $0 0.24 $75,047 ($310,669) 0.26 $82,327 ($310,669)
Uniqure N.V. -- $0 $0 0.00 $0 ($1,073,852) 0.00 $0 ($1,223,716)
Ultragenyx Pharmaceutical Inc. -- $0 $0 0.00 $0 ($7,718,399) 0.00 $0 ($10,789,815)
Vertex Pharmaceuticals Inc / Ma -- $0 $0 0.00 $0 ($28,311,810) 0.00 $0 ($68,927,337)
Mannkind Corp -- $0 $0 0.00 $0 ($403,700) 0.00 $0 ($1,960,064)
Verona Pharma Plc -- $0 $0 0.04 $476,066 ($13,037,640) 0.02 $579,386 ($26,001,975)
Syndax Pharmaceuticals Inc -- $0 $0 0.00 $0 ($336,173) 0.07 $25,037 ($336,173)
Chimerix Inc -- $0 $0 0.00 $0 ($91,140) 0.00 $0 ($92,205)
Abbvie Inc. -- $0 $0 0.00 $0 ($29,625,038) 0.00 $0 ($42,028,618)
Nuvectis Pharma, Inc. -- $0 $0 5.75 $129,305 ($22,478) 7.36 $165,360 ($22,478)
Lifevantage Corp -- $0 $0 0.01 $3,632 ($364,620) 0.05 $17,613 ($364,620)
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $0 ($9,180,595) 0.00 $0 ($21,239,184)
Alnylam Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($8,371,620) 0.00 $0 ($13,644,367)
Aclaris Therapeutics, Inc. -- $0 $0 -- $1,499,998 $0 -- $1,499,998 $0
Vera Therapeutics, Inc. -- $0 $0 0.00 $0 ($546,914) 0.00 $0 ($2,539,065)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,179,076) 0.00 $0 ($1,239,536)
GYRE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($1,342,488) 0.00 $0 ($1,342,488)
Zoetis Inc. -- $0 $0 0.00 $0 ($256,449) 0.00 $0 ($256,449)
Nuvalent, Inc. -- $0 $0 0.00 $0 ($113,455,115) 0.00 $0 ($221,428,919)
Wave Life Sciences Ltd. -- $0 $0 0.00 $0 ($733,671) 0.00 $0 ($2,524,650)
Nektar Therapeutics -- $0 $0 0.00 $0 ($300,838) 0.00 $0 ($412,271)
Abbott Laboratories -- $0 $0 0.00 $0 ($886,045) 0.00 $0 ($3,317,264)
Alkermes Plc. -- $0 $0 0.00 $0 ($1,192,994) 0.00 $0 ($1,192,994)
Xeris Biopharma Holdings, Inc. -- $0 $0 0.00 $0 ($217,244) 0.14 $30,595 ($217,244)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($6,887,672) 0.00 $0 ($44,526,907)
Ardelyx, Inc. -- $0 $0 5.08 $3,374,588 ($663,814) 1.13 $3,374,588 ($2,995,311)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($2,459,665) 0.00 $0 ($5,073,324)
Abcellera Biologics Inc. -- $0 $0 -- $198,068 $0 -- $198,068 $0
Tvardi Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,365) 0.00 $0 ($10,769)
Ligand Pharmaceuticals Inc -- $0 $0 0.00 $0 ($819,999) 0.04 $243,480 ($6,309,524)
Altimmune, Inc. -- $0 $0 -- $57,780 $0 -- $57,780 $0
Vanda Pharmaceuticals Inc. -- $0 $0 13.29 $343,669 ($25,863) 8.77 $343,669 ($39,190)
Ironwood Pharmaceuticals Inc -- $0 $0 0.00 $0 ($495,086) 0.00 $0 ($2,010,554)
Elanco Animal Health Inc -- $0 $0 -- $483,558 $0 -- $2,090,842 $0
Dyne Therapeutics, Inc. -- $0 $0 0.00 $0 ($12,504,416) 0.00 $264,304 ($100,209,638)
Dynavax Technologies Corp -- $0 $0 0.00 $0 ($661,866) 0.00 $0 ($704,993)
Perrigo Co Plc -- $0 $0 0.00 $0 ($497,495) 0.01 $27,900 ($2,092,745)
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 0.00 $0 ($130,241) 0.00 $0 ($130,241)
Evolus, Inc. -- $0 $0 0.00 $0 ($2,320,078) 0.00 $0 ($3,327,330)
Cryoport, Inc. -- $0 $0 0.00 $0 ($113,518) 0.00 $0 ($295,114)
Generation Bio Co. -- $0 $0 -- $203,209 $0 11.04 $203,209 ($18,410)
Organogenesis Holdings Inc. -- $0 $0 0.00 $0 ($1,273,959) 0.00 $0 ($1,273,959)
Ibio, Inc. -- $0 $0 -- $654,995 $0 -- $654,995 $0
Spyre Therapeutics, Inc. -- $0 $0 0.00 $0 ($246,313) 0.00 $0 ($779,316)
Viatris Inc -- $0 $0 0.00 $0 ($346,686) 0.00 $0 ($11,918,920)
Optinose, Inc. -- $0 $0 0.00 $0 ($58,362) 0.00 $0 ($287,300)
Johnson & Johnson -- $0 $0 -- $147,220 $0 -- $147,220 $0
Arcus Biosciences, Inc. -- $0 $0 7.07 $402,665 ($56,989) 5.21 $402,665 ($77,304)
Applied Therapeutics, Inc. -- $0 $0 0.00 $0 ($94,797) 0.00 $0 ($5,453,317)
Oragenics Inc -- $0 $0 0.00 $0 ($1,319) 0.00 $0 ($1,319)
Igm Biosciences, Inc. -- $0 $0 0.00 $0 ($65,113) 0.00 $0 ($282,116)
Alzamend Neuro, Inc. -- $0 $0 -- $21,072 $0 -- $21,372 $0
CalciMedica, Inc. -- $0 $0 -- $888,469 $0 -- $1,344,745 $0
Ionis Pharmaceuticals Inc -- $0 $0 0.06 $181,079 ($2,982,297) 0.05 $181,079 ($3,387,372)
Assertio Holdings, Inc. -- $0 $0 -- $69,950 $0 -- $105,300 $0
Disc Medicine, Inc. -- $0 $0 0.00 $0 ($41,103,384) 0.34 $14,000,076 ($41,250,384)
Annexon, Inc. -- $0 $0 0.13 $17,056 ($126,438) 0.44 $120,106 ($274,048)
Longeveron Inc. -- $0 $0 0.00 $0 ($2,588) 0.00 $0 ($2,588)
Schrodinger, Inc. -- $0 $0 0.00 $0 ($230,658) 0.00 $0 ($257,884)
Alaunos Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,022) 0.00 $0 ($6,022)
Bespoke Extracts, Inc. -- $0 $0 -- $3,245 $0 -- $6,208 $0
Avalo Therapeutics, Inc. -- $0 $0 -- $12,750 $0 -- $12,750 $0
Fibrogen Inc -- $0 $0 -- $155,703 $0 -- $181,587 $0
Beigene, Ltd. -- $0 $0 0.00 $0 ($388,736,608) 0.00 $0 ($398,442,914)
Emergent Biosolutions Inc. -- $0 $0 0.00 $0 ($705,115) 0.00 $0 ($780,946)
Cue Biopharma, Inc. -- $0 $0 -- $30,900 $0 -- $30,900 $0
Nkarta, Inc. -- $0 $0 0.00 $0 ($107,547) 0.00 $0 ($155,088)
Zomedica Corp. -- $0 $0 -- $382,326 $0 -- $655,524 $0
Neurogene Inc. -- $0 $0 19.15 $1,460,400 ($76,247) 19.15 $1,460,400 ($76,247)
Aquestive Therapeutics, Inc. -- $0 $0 0.00 $0 ($214) 0.00 $0 ($214)
Arbutus Biopharma Corp -- $0 $0 0.00 $0 ($251,655) 0.00 $0 ($251,655)
Phibro Animal Health Corp -- $0 $0 -- $110,500 $0 -- $210,600 $0
ALT5 Sigma Corp -- $0 $0 -- $9,000 $0 -- $19,278 $0
Anaptysbio, Inc -- $0 $0 -- $1,099,642 $0 13.62 $1,099,642 ($80,762)
Galera Therapeutics, Inc. -- $0 $0 -- $499,979 $0 103.62 $499,979 ($4,825)
Vtv Therapeutics Inc. -- $0 $0 -- $83,812 $0 -- $83,812 $0
Immunic, Inc. -- $0 $0 -- $100,369 $0 -- $100,369 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $8,400 $0 -- $8,400 $0
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($1,696,872) 0.00 $0 ($1,696,872)
Mirum Pharmaceuticals, Inc. -- $0 $0 0.16 $280,117 ($1,756,062) 0.17 $293,981 ($1,756,062)
Sarepta Therapeutics, Inc. -- $0 $0 0.00 $0 ($205,400) 3.23 $4,955,728 ($1,536,399)
Veru Inc. -- $0 $0 -- $84,351 $0 0.32 $106,047 ($334,454)
MARINUS PHARMACEUTICALS, INC. -- $0 $0 0.00 $0 ($1,733) 0.19 $6,526 ($34,622)
Alx Oncology Holdings Inc -- $0 $0 1.66 $46,404 ($27,952) 0.45 $148,742 ($328,923)
Vyne Therapeutics Inc. -- $0 $0 -- $43,800 $0 -- $43,800 $0
Kura Oncology, Inc. -- $0 $0 0.00 $0 ($187,590) 0.00 $0 ($245,507)
Avidity Biosciences, Inc. -- $0 $0 0.00 $0 ($5,398,236) 0.00 $0 ($15,312,081)
Marker Therapeutics, Inc. -- $0 $0 -- $35,472 $0 -- $35,472 $0
Pliant Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,501,298) 0.00 $0 ($2,420,272)
Design Therapeutics, Inc. -- $0 $0 0.00 $0 ($23,864) 0.00 $0 ($3,487,078)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($47,888) 0.00 $0 ($47,888)
Prelude Therapeutics Inc -- $0 $0 -- $876,166 $0 -- $876,166 $0
Supernus Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($316,434) 0.00 $0 ($316,434)
Cogent Biosciences, Inc. -- $0 $0 -- $332,412 $0 -- $332,412 $0
Avenue Therapeutics, Inc. -- $0 $0 0.00 $0 ($183) 6.84 $1,250 ($183)
Pfizer Inc -- $0 $0 7.70 $499,072 ($64,825) 2.48 $527,312 ($212,539)
Merck & Co., Inc. -- $0 $0 1.10 $1,577,424 ($1,436,352) 1.10 $1,577,424 ($1,436,352)
ZEVRA THERAPEUTICS, INC. -- $0 $0 0.09 $81,976 ($919,975) 0.25 $226,199 ($919,975)
Silo Pharma, Inc. -- $0 $0 -- $6,722 $0 -- $12,255 $0
Cormedix Inc. -- $0 $0 -- $14,985 $0 -- $14,985 $0
Ocular Therapeutix, Inc -- $0 $0 0.00 $0 ($593,751) 0.00 $0 ($937,108)
Immunome Inc. -- $0 $0 -- $3,693,690 $0 -- $5,206,510 $0
Verrica Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($2,805) 0.00 $0 ($1,080,006)
Equillium, Inc. -- $0 $0 0.00 $0 ($13,500) 0.00 $0 ($86,433)
Janux Therapeutics, Inc. -- $0 $0 5.36 $25,342,965 ($4,731,473) 1.53 $79,042,965 ($51,723,396)
Pds Biotechnology Corp -- $0 $0 -- $50,001 $0 -- $50,001 $0
Atai Life Sciences N.V. -- $0 $0 0.00 $0 ($246,038) 0.00 $0 ($536,539)
Atossa Therapeutics, Inc. -- $0 $0 -- $7,000 $0 -- $7,000 $0
Ovid Therapeutics Inc. -- $0 $0 0.97 $4,971 ($5,141) 0.97 $4,971 ($5,141)
Catalyst Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($696,382) 0.00 $0 ($3,957,416)
Revance Therapeutics, Inc. -- $0 $0 0.00 $0 ($16,296) 0.00 $0 ($16,296)
Opus Genetics, Inc. -- $0 $0 -- $208,592 $0 -- $223,542 $0
Forte Biosciences, Inc. -- $0 $0 -- $124,998 $0 -- $124,998 $0
Acurx Pharmaceuticals, Inc. -- $0 $0 -- $170,000 $0 -- $170,000 $0
Tyra Biosciences, Inc. -- $0 $0 5.17 $19,836,066 ($3,839,088) 2.50 $19,988,021 ($7,987,211)
Nrx Pharmaceuticals, Inc. -- $0 $0 -- $46,800 $0 -- $46,800 $0
Io Biotech, Inc. -- $0 $0 -- $54,876 $0 -- $54,876 $0
Pyxis Oncology, Inc. -- $0 $0 -- $10,900 $0 -- $10,900 $0
Immix Biopharma, Inc. -- $0 $0 -- $104,358 $0 -- $236,578 $0
Atea Pharmaceuticals, Inc. -- $0 $0 0.08 $81,498 ($1,023,475) 0.06 $81,498 ($1,322,798)
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($288,395) 0.00 $0 ($345,732)
Geron Corp -- $0 $0 -- $206,212 $0 -- $206,212 $0
Madrigal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($5,977,621) 0.00 $0 ($7,768,779)
AYTU BIOPHARMA, INC -- $0 $0 -- $19,500 $0 -- $19,500 $0
Oncotelic Therapeutics, Inc. -- $0 $0 -- $18,338 $0 -- $28,338 $0
Rein Therapeutics, Inc. -- $0 $0 -- $898 $0 -- $898 $0
Skye Bioscience, Inc. -- $0 $0 0.00 $0 ($1,159,462) 0.00 $0 ($2,646,785)
Avadel Pharmaceuticals Plc -- $0 $0 -- $761,675 $0 -- $761,675 $0
Tango Therapeutics, Inc. -- $0 $0 0.52 $74,000 ($143,227) 0.69 $74,000 ($107,188)
Cassava Sciences Inc -- $0 $0 0.00 $0 ($15,480) 0.00 $0 ($15,480)
Earth Science Tech, Inc. -- $0 $0 -- $305,362 $0 -- $545,197 $0
Maravai Lifesciences Holdings, Inc. -- $0 $0 8.65 $1,087,625 ($125,750) 8.65 $1,087,625 ($125,750)
Rigel Pharmaceuticals Inc -- $0 $0 0.00 $0 ($424,179) 0.00 $0 ($424,179)
An2 Therapeutics, Inc. -- $0 $0 20.47 $483,337 ($23,610) 20.47 $483,337 ($23,610)
Promis Neurosciences Inc. -- $0 $0 -- $14,595 $0 -- $282,837 $0
Lexaria Bioscience Corp. -- $0 $0 -- $118,392 $0 12.02 $123,400 ($10,268)
Rani Therapeutics Holdings, Inc. -- $0 $0 -- $49,967 $0 -- $49,967 $0
Anebulo Pharmaceuticals, Inc. -- $0 $0 -- $10,000,000 $0 -- $10,000,000 $0
Maia Biotechnology, Inc. -- $0 $0 -- $1,003,625 $0 -- $1,003,625 $0
Biohaven Ltd. -- $0 $0 -- $2,038,632 $0 -- $8,791,598 $0
Journey Medical Corp -- $0 $0 0.00 $0 ($818,145) 0.00 $0 ($891,044)
Serina Therapeutics, Inc. -- $0 $0 -- $17,745 $0 -- $730,976 $0
Quoin Pharmaceuticals, Ltd. -- $0 $0 -- $600,000 $0 3131.76 $680,858 ($217)
Entero Therapeutics, Inc. -- $0 $0 0.00 $0 ($465) 0.00 $0 ($2,721)
BIOADAPTIVES, INC. -- $0 $0 -- $10,625 $0 -- $10,625 $0
NewAmsterdam Pharma Co N.V. -- $0 $0 -- $109,724 $0 -- $294,715 $0
GENELUX CORP -- $0 $0 0.00 $0 ($67,545) 0.00 $0 ($104,234)
Coya Therapeutics, Inc. -- $0 $0 -- $106,393 $0 -- $106,393 $0
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $117,523 $0 -- $126,023 $0
ACELYRIN, Inc. -- $0 $0 0.00 $0 ($68,902) 0.00 $0 ($68,909)
MIRA PHARMACEUTICALS, INC. -- $0 $0 0.00 $0 ($133,649) 0.06 $8,176 ($133,649)
Mural Oncology plc -- $0 $0 0.00 $0 ($135,028) 0.18 $32,071 ($178,849)
Kairos Pharma, LTD. -- $0 $0 -- $9,828 $0 -- $9,828 $0
Nika Pharmaceuticals, Inc -- $0 $0 0.00 $0 ($500,000) 0.00 $0 ($500,000)
Contineum Therapeutics, Inc. -- $0 $0 0.00 $0 ($117,598) 0.00 $0 ($117,598)
Zenas Biopharma, Inc. -- $0 $0 -- $1,111,375 $0 -- $2,472,186 $0
Septerna, Inc. -- $0 $0 -- $934,328 $0 -- $934,328 $0
Emmaus Life Sciences, Inc. -- $0 $0 -- $0 $0 -- $800 $0
Precigen, Inc. -- $0 $0 -- $0 $0 -- $20,049,999 $0
G1 Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($441,370)
Kezar Life Sciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($3,879)
Regeneron Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($132,396,942)
Arcturus Therapeutics Holdings Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,895,985)
Verve Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $475,760 $0
Keros Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($22,005,000)
Tempest Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $100,001 $0
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $155,961 $0
Reshape Lifesciences Inc. -- $0 $0 -- $0 $0 0.00 $0 ($12)
Clene Inc. -- $0 $0 -- $0 $0 -- $583,390 $0
Eyenovia, Inc. -- $0 $0 -- $0 $0 -- $42,577 $0
Vaccinex, Inc. -- $0 $0 -- $0 $0 -- $1,325,527 $0
Imunon, Inc. -- $0 $0 -- $0 $0 -- $79,730 $0
Roivant Sciences Ltd. -- $0 $0 -- $0 $0 0.00 $0 ($57,098,536)
Glycomimetics Inc -- $0 $0 -- $0 $0 -- $83,159 $0
Cingulate Inc. -- $0 $0 -- $0 $0 0.00 $0 ($841)
Gossamer Bio, Inc. -- $0 $0 -- $0 $0 257.45 $324,442 ($1,260)
Protokinetix, Inc. -- $0 $0 -- $0 $0 -- $85,000 $0
Adicet Bio, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($8,437)
Relmada Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $642,845 $0
Fulcrum Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,831)
Lumos Pharma, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,426)
KIORA PHARMACEUTICALS INC -- $0 $0 -- $0 $0 -- $95,206 $0
Bioxcel Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($423,308)
Amarin Corp Plc\Uk -- $0 $0 -- $0 $0 -- $102,400 $0
Monopar Therapeutics -- $0 $0 -- $0 $0 -- $125,187 $0
Allakos Inc. -- $0 $0 -- $0 $0 0.00 $0 ($87,935)
Phio Pharmaceuticals Corp. -- $0 $0 -- $0 $0 -- $1,490 $0
Essa Pharma Inc. -- $0 $0 -- $0 $0 0.00 $0 ($25,727)
IGC Pharma, Inc. -- $0 $0 -- $0 $0 -- $200,000 $0
Pmv Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($15,200)
Fortress Biotech, Inc. -- $0 $0 -- $0 $0 76.98 $1,454,894 ($18,900)
Corvus Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $1,034,624 $0
CervoMed Inc. -- $0 $0 -- $0 $0 -- $18,160 $0
Kronos Bio, Inc. -- $0 $0 -- $0 $0 -- $3,852,882 $0
Palatin Technologies Inc -- $0 $0 -- $0 $0 0.00 $0 ($8,274)
Aerovate Therapeutics, Inc. -- $0 $0 -- $0 $0 37.23 $1,549,944 ($41,631)
Erasca, Inc. -- $0 $0 -- $0 $0 -- $181,920 $0
Aridis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $100,000 $0
Climb Bio, Inc. -- $0 $0 -- $0 $0 16.07 $49,952,817 ($3,108,685)
Axsome Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($789,107)
Aldeyra Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($127,288)
Natures Sunshine Products Inc -- $0 $0 -- $0 $0 0.00 $0 ($46,940)
Hoth Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $16,750 $0
MoonLake Immunotherapeutics -- $0 $0 -- $0 $0 0.00 $0 ($109,189,320)
Foghorn Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($190,000)
Scynexis Inc -- $0 $0 -- $0 $0 -- $27,400 $0
Gain Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $85,154 $0
Whitehawk Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($331,582)
Third Harmonic Bio, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($352,654)
ADC Therapeutics SA -- $0 $0 -- $0 $0 0.00 $0 ($225,811)
CONDUIT PHARMACEUTICALS INC. -- $0 $0 -- $0 $0 0.00 $0 ($4,592,487)
Mereo Biopharma Group plc -- $0 $0 -- $0 $0 0.00 $0 ($2,315,682)
BriaCell Therapeutics Corp. -- $0 $0 -- $0 $0 -- $2,000,001 $0
Flora Growth Corp. -- $0 $0 -- $0 $0 -- $30,759 $0
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 -- $0 $0 0.00 $0 ($562,305)
LIPELLA PHARMACEUTICALS INC. -- $0 $0 -- $0 $0 -- $7,590 $0
Bio Essence Corp -- $0 $0 -- $0 $0 0.00 $0 ($2,492,803)
Sagimet Biosciences Inc. -- $0 $0 -- $0 $0 0.00 $0 ($178,175)
FibroBiologics, Inc. -- $0 $0 -- $0 $0 -- $35,269 $0
Alto Neuroscience, Inc. -- $0 $0 -- $0 $0 -- $190,833 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($85,024)
Bioage Labs, Inc. -- $0 $0 -- $0 $0 -- $4,430,395 $0