Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 12/10/2025 10:05:24 PM
1 Month
Buy/Sell Ratio 0.33
24%
76%
Buy Sell
$103.22 M ($312.02) M
65 Insiders 154 Insiders
144 Transactions 245 Transactions
11/10/2025 to 12/10/2025
3 Month
Buy/Sell Ratio 0.44
30%
70%
Buy Sell
$214.36 M ($489.14) M
118 Insiders 285 Insiders
227 Transactions 565 Transactions
9/10/2025 to 12/10/2025
6 Month
Buy/Sell Ratio 1.10
52%
48%
Buy Sell
$813.59 M ($742.33) M
223 Insiders 468 Insiders
653 Transactions 1117 Transactions
6/10/2025 to 12/10/2025
12 Month
Buy/Sell Ratio 0.81
44%
56%
Buy Sell
$1,175.85 M ($1,445.33) M
429 Insiders 796 Insiders
1515 Transactions 2408 Transactions
12/10/2024 to 12/10/2025

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Bausch Health Companies Inc.
$369,628,560 8
Madrigal Pharmaceuticals, Inc.
$61,921,024 3
Zymeworks Inc.
$58,036,053 36
89Bio, Inc.
$49,999,994 1
Mineralys Therapeutics, Inc.
$47,499,981 2
Benitec Biopharma Inc.
$32,438,904 5
Larimar Therapeutics, Inc.
$30,000,000 3
Pepgen Inc.
$30,000,000 1
Biohaven Ltd.
$27,038,629 6
Aurinia Pharmaceuticals Inc.
$26,303,126 6

Most Insider Selling

12 months
Name Value Transactions
BeOne Medicines Ltd.
($190,535,020) 1
Nuvalent, Inc.
($110,000,000) 1
Bridgebio Pharma, Inc.
($59,157,004) 31
Mineralys Therapeutics, Inc.
($43,350,000) 1
Nuvalent, Inc.
($35,437,488) 1
Roivant Sciences Ltd.
($26,304,500) 1
Roivant Sciences Ltd.
($26,304,500) 1
Corcept Therapeutics Inc
($25,078,150) 13
Sionna Therapeutics, Inc.
($22,085,832) 26
Sionna Therapeutics, Inc.
($21,463,466) 7

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Eli Lilly & Co 8 8
Mbx Biosciences, Inc. 6 9
Hcw Biologics Inc. 6 8
Zenas Biopharma, Inc. 6 8
Organon & Co. 6 7
Perrigo Co Plc 5 8
Zomedica Corp. 5 6
Quoin Pharmaceuticals, Ltd. 5 5
ALUMIS INC. 4 21
Relmada Therapeutics, Inc. 4 13

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Ani Pharmaceuticals Inc 15 35
Apellis Pharmaceuticals, Inc. 12 42
Ionis Pharmaceuticals Inc 12 32
Insmed Inc 11 67
Blueprint Medicines Corp 11 24
Puma Biotechnology, Inc. 11 14
Liquidia Corp 10 26
Arrowhead Pharmaceuticals, Inc. 10 23
Uniqure N.V. 10 15
Disc Medicine, Inc. 9 38

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Wave Life Sciences Ltd. 0.01 $6,688 ($596,179) 0.00 $6,688 ($3,237,173) 0.00 $6,688 ($3,237,173)
Roivant Sciences Ltd. 0.00 $0 ($52,609,000) 0.00 $49,957 ($52,609,000) 0.00 $49,957 ($52,609,000)
Mineralys Therapeutics, Inc. 0.00 $0 ($52,438,499) 0.81 $44,999,978 ($55,853,419) 1.31 $74,099,970 ($56,607,626)
Nuvalent, Inc. 0.00 $0 ($37,039,298) 0.00 $0 ($43,054,763) 0.00 $0 ($156,317,435)
Insmed Inc 0.00 $0 ($21,774,049) 0.00 $0 ($31,425,459) 0.00 $201,694 ($71,707,456)
Royalty Pharma Plc 0.00 $0 ($21,046,759) 0.00 $0 ($21,046,759) 0.00 $0 ($21,046,759)
Sionna Therapeutics, Inc. 0.00 $0 ($16,329,272) 0.00 $0 ($55,144,342) 0.00 $0 ($55,144,342)
Bridgebio Pharma, Inc. 0.00 $0 ($15,224,286) 0.00 $0 ($71,984,008) 0.00 $0 ($105,503,006)
Precigen, Inc. 0.00 $0 ($12,291,748) 0.01 $235,938 ($19,066,904) 0.01 $235,938 ($19,066,904)
Vertex Pharmaceuticals Inc / Ma 0.00 $0 ($9,651,208) 0.58 $5,844,183 ($10,034,589) 0.20 $5,844,183 ($29,181,869)
Tyra Biosciences, Inc. 0.00 $0 ($9,139,017) 0.17 $1,664,700 ($9,767,280) 1.48 $15,320,006 ($10,329,715)
BeOne Medicines Ltd. 0.00 $0 ($7,365,123) 0.00 $0 ($31,877,782) 0.00 $0 ($228,733,017)
MoonLake Immunotherapeutics 0.00 $0 ($5,987,162) 0.02 $98,808 ($5,987,162) 0.02 $98,808 ($5,987,162)
Jazz Pharmaceuticals Plc 0.00 $0 ($5,458,839) 0.00 $0 ($7,204,929) 0.91 $9,993,082 ($11,003,601)
Leap Therapeutics, Inc. 0.00 $0 ($5,069,461) 0.00 $0 ($5,069,461) 0.00 $0 ($5,069,461)
Corcept Therapeutics Inc 0.00 $0 ($3,918,937) 0.00 $0 ($16,138,269) 0.00 $0 ($27,786,242)
Arcus Biosciences, Inc. 0.00 $0 ($3,188,363) 0.00 $0 ($5,442,152) 0.07 $402,665 ($5,496,062)
Stoke Therapeutics, Inc. 0.00 $0 ($2,856,573) 0.00 $0 ($6,174,474) 0.00 $0 ($6,784,411)
Ionis Pharmaceuticals Inc 0.00 $0 ($2,262,848) 0.00 $0 ($13,832,388) 0.04 $658,979 ($16,005,686)
Ani Pharmaceuticals Inc 0.00 $0 ($2,244,317) 0.00 $0 ($34,496,773) 0.00 $0 ($35,703,291)
Teva Pharmaceutical Industries Ltd 0.00 $0 ($2,054,826) 0.00 $20,988 ($8,129,734) 0.00 $20,988 ($23,407,634)
Theravance Biopharma, Inc. 0.00 $0 ($1,981,771) 0.00 $0 ($2,095,640) 0.00 $0 ($2,431,640)
Arcutis Biotherapeutics, Inc. 0.00 $0 ($1,941,764) 0.00 $34,610 ($6,965,027) 0.04 $373,039 ($9,578,496)
Entrada Therapeutics, Inc. 0.00 $0 ($1,848,932) 0.00 $0 ($2,918,118) 0.00 $0 ($2,937,153)
Organogenesis Holdings Inc. 0.00 $0 ($1,592,120) 0.00 $0 ($1,592,120) 0.67 $1,821,329 ($2,733,851)
Arrowhead Pharmaceuticals, Inc. 0.00 $0 ($1,485,150) 0.00 $0 ($3,210,150) 0.00 $0 ($9,389,909)
Phibro Animal Health Corp 0.00 $0 ($1,177,833) 0.00 $0 ($5,958,604) 0.02 $110,500 ($5,958,604)
Xenon Pharmaceuticals Inc. 0.00 $0 ($1,146,879) 0.00 $0 ($1,146,879) 0.00 $0 ($1,146,971)
Madrigal Pharmaceuticals, Inc. 0.00 $0 ($1,082,986) 7.88 $61,921,024 ($7,854,110) 5.49 $61,921,024 ($11,287,540)
Eli Lilly & Co 0.00 $0 ($1,010,500) 1.79 $4,537,301 ($2,529,192) 0.49 $4,537,301 ($9,316,457)
Cormedix Inc. 0.00 $0 ($817,800) 0.34 $275,500 ($817,800) 0.34 $275,500 ($817,800)
Werewolf Therapeutics, Inc. 0.00 $0 ($708,474) 0.00 $0 ($1,521,718) 0.32 $487,188 ($1,521,718)
Enliven Therapeutics, Inc. 0.00 $0 ($691,966) 0.00 $0 ($3,969,357) 0.00 $0 ($6,082,642)
Amneal Pharmaceuticals, Inc. 0.00 $0 ($586,000) 0.00 $0 ($9,091,532) 0.00 $0 ($16,539,804)
Kura Oncology, Inc. 0.00 $0 ($498,680) 0.60 $713,346 ($1,196,690) 0.51 $713,346 ($1,394,916)
Rapport Therapeutics, Inc. 0.00 $0 ($489,138) 0.45 $1,605,585 ($3,546,859) 0.47 $1,767,823 ($3,801,636)
Cytokinetics Inc 0.00 $0 ($467,270) 0.00 $0 ($3,968,091) 0.00 $0 ($12,031,623)
Ardelyx, Inc. 0.00 $0 ($452,741) 0.76 $725,880 ($960,204) 3.83 $5,781,187 ($1,511,019)
Spyre Therapeutics, Inc. 0.00 $0 ($435,356) 0.00 $0 ($1,784,773) 0.00 $0 ($1,784,773)
Natures Sunshine Products Inc 0.00 $0 ($363,095) 0.00 $0 ($772,898) 0.00 $0 ($772,898)
Ocular Therapeutix, Inc 0.00 $0 ($335,663) 0.00 $0 ($1,341,101) 0.03 $69,600 ($1,999,856)
Verastem, Inc. 0.00 $0 ($331,860) 0.00 $0 ($579,968) 0.00 $0 ($1,220,163)
Sagimet Biosciences Inc. 0.00 $0 ($289,979) 0.00 $0 ($1,062,172) 0.00 $0 ($1,062,172)
Centessa Pharmaceuticals Plc 0.00 $0 ($288,289) 0.00 $0 ($589,886) 1.03 $5,865,242 ($5,715,183)
Zai Lab Ltd 0.00 $0 ($283,408) 0.28 $289,100 ($1,020,458) 0.09 $289,100 ($3,201,350)
Ptc Therapeutics, Inc. 0.00 $0 ($271,052) 0.00 $0 ($1,034,729) 0.00 $0 ($4,563,920)
Amicus Therapeutics, Inc. 0.00 $0 ($258,933) 0.00 $0 ($502,793) 0.00 $0 ($502,793)
Urogen Pharma Ltd. 0.00 $0 ($250,000) 0.00 $0 ($426,900) 0.00 $0 ($426,900)
Xeris Biopharma Holdings, Inc. 0.00 $0 ($240,076) 0.08 $109,475 ($1,455,372) 0.07 $109,475 ($1,672,616)
Prestige Consumer Healthcare Inc. 0.00 $0 ($238,050) 0.00 $0 ($238,050) 0.00 $0 ($389,070)
Protagonist Therapeutics, Inc 0.00 $0 ($229,896) 0.00 $0 ($4,174,474) 0.00 $0 ($4,676,856)
Nektar Therapeutics 0.00 $0 ($216,794) 0.00 $0 ($1,155,577) 0.00 $0 ($1,455,064)
Abbott Laboratories 0.00 $0 ($203,043) 0.00 $0 ($949,801) 0.00 $0 ($2,172,962)
Enanta Pharmaceuticals Inc 0.00 $0 ($183,167) 0.00 $0 ($183,167) 1.40 $256,050 ($183,167)
Collegium Pharmaceutical, Inc 0.00 $0 ($171,673) 0.00 $0 ($2,459,644) 0.00 $0 ($4,919,309)
Fulcrum Therapeutics, Inc. 0.00 $0 ($165,495) 0.00 $0 ($165,495) 0.00 $0 ($168,015)
Tg Therapeutics, Inc. 0.00 $0 ($162,850) 0.00 $0 ($1,204,518) 0.00 $0 ($1,833,901)
Harmony Biosciences Holdings, Inc. 0.00 $0 ($119,945) 0.00 $0 ($907,323) 0.00 $0 ($1,134,709)
Alkermes Plc. 0.00 $0 ($117,200) 0.00 $0 ($117,200) 0.00 $0 ($327,343)
Q32 Bio Inc. 0.00 $0 ($109,266) 0.00 $0 ($141,187) 0.00 $0 ($141,187)
Vera Therapeutics, Inc. 0.00 $0 ($107,498) 49.09 $5,277,311 ($107,498) 8.06 $5,277,311 ($654,412)
Apellis Pharmaceuticals, Inc. 0.00 $0 ($100,300) 0.00 $0 ($9,727,956) 0.00 $0 ($12,812,912)
Puma Biotechnology, Inc. 0.00 $0 ($97,228) 0.00 $0 ($727,675) 0.00 $0 ($923,516)
Pacira Biosciences, Inc. 0.00 $0 ($95,396) 0.00 $0 ($542,074) 0.00 $0 ($1,091,553)
Mannkind Corp 0.00 $0 ($94,448) 0.00 $0 ($671,790) 0.00 $0 ($1,518,088)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($94,418) 0.00 $0 ($1,659,825) 0.02 $37,005 ($2,124,288)
Ligand Pharmaceuticals Inc 0.00 $0 ($91,457) 0.00 $0 ($2,283,717) 0.35 $1,156,546 ($3,264,987)
United Therapeutics Corp 0.00 $0 ($90,065) 0.00 $0 ($1,305,081) 0.00 $0 ($1,395,801)
Lifevantage Corp 0.00 $0 ($80,934) 0.03 $9,756 ($379,977) 0.03 $24,400 ($744,597)
Dyne Therapeutics, Inc. 0.00 $0 ($76,374) 4.94 $911,000 ($184,413) 1.61 $911,000 ($565,212)
Abeona Therapeutics Inc. 0.00 $0 ($71,168) 0.00 $0 ($1,467,133) 0.00 $0 ($2,220,394)
GENELUX CORP 0.00 $0 ($52,624) 0.00 $0 ($58,748) 0.00 $0 ($204,590)
Rocket Pharmaceuticals, Inc. 0.00 $0 ($34,463) 0.13 $34,100 ($260,439) 0.31 $234,865 ($767,802)
Ironwood Pharmaceuticals Inc 0.00 $0 ($19,973) 0.00 $0 ($31,045) 0.00 $0 ($468,609)
Liquidia Corp 0.00 $0 ($16,868) 0.00 $0 ($23,911,969) 0.00 $0 ($25,375,464)
Equillium, Inc. 0.00 $0 ($7,696) 0.00 $0 ($7,696) 0.00 $0 ($14,196)
Rockwell Medical, Inc. 0.00 $0 ($4,419) 0.00 $0 ($29,298) 0.00 $0 ($47,348)
Galera Therapeutics, Inc. 0.00 $0 ($1,407) 0.00 $0 ($1,407) 355.35 $499,979 ($1,407)
Aditxt, Inc. 0.00 $0 ($3) 0.00 $0 ($3) 0.00 $0 ($3)
Catalyst Pharmaceuticals, Inc. -0.00 $0 $908,000 -0.00 $0 $865,728 0.00 $0 ($3,369,170)
Biohaven Ltd. -- $33,144,763 $0 -- $33,144,763 $0 -- $35,183,395 $0
CRESCENT BIOPHARMA, INC. -- $18,237,600 $0 -- $18,237,600 $0 -- $18,237,600 $0
Verrica Pharmaceuticals Inc. -- $17,972,698 $0 -- $17,972,698 $0 6407.95 $17,972,698 ($2,805)
ALUMIS INC. -- $12,697,142 $0 -- $12,697,142 $0 -- $14,607,031 $0
Annexon, Inc. -- $8,812,448 $0 1110.08 $8,866,766 ($7,987) 65.96 $8,866,766 ($134,425)
Opko Health, Inc. -- $2,978,156 $0 -- $4,082,591 $0 -- $7,331,081 $0
XOMA Royalty Corp -- $2,505,000 $0 -- $2,555,780 $0 -- $3,265,508 $0
Maravai Lifesciences Holdings, Inc. -- $1,880,244 $0 -- $1,880,244 $0 14.95 $1,880,244 ($125,750)
CervoMed Inc. -- $737,723 $0 -- $737,723 $0 -- $773,534 $0
Cassava Sciences Inc -- $640,749 $0 -- $1,231,784 $0 -- $1,231,784 $0
Annovis Bio, Inc. -- $615,116 $0 -- $2,815,117 $0 -- $2,815,117 $0
Organon & Co. -- $501,755 $0 -- $501,755 $0 -- $1,153,382 $0
Johnson & Johnson -- $257,688 $0 0.08 $257,688 ($3,129,830) 0.13 $404,908 ($3,129,830)
Maia Biotechnology, Inc. -- $209,793 $0 -- $234,792 $0 -- $834,088 $0
Cartesian Therapeutics, Inc. -- $205,797 $0 -- $205,797 $0 7.26 $4,430,843 ($610,064)
Tenax Therapeutics, Inc. -- $204,468 $0 -- $204,468 $0 -- $204,468 $0
Edgewise Therapeutics, Inc. -- $199,403 $0 -- $199,403 $0 -- $20,199,404 $0
NEONC TECHNOLOGIES HOLDINGS, INC. -- $192,019 $0 -- $192,019 $0 -- $399,908 $0
Abcellera Biologics Inc. -- $178,460 $0 -- $178,460 $0 -- $376,528 $0
Biomea Fusion, Inc. -- $153,732 $0 -- $153,732 $0 -- $153,732 $0
Pasithea Therapeutics Corp. -- $149,999 $0 -- $149,999 $0 189.39 $149,999 ($792)
BIOXYTRAN, INC -- $126,000 $0 -- $126,000 $0 -- $126,000 $0
Turn Therapeutics Inc. -- $108,997 $0 -- $233,995 $0 -- $233,995 $0
Perrigo Co Plc -- $106,350 $0 -- $562,500 $0 -- $657,350 $0
Sellas Life Sciences Group, Inc. -- $100,806 $0 -- $115,606 $0 -- $185,406 $0
Rezolute, Inc. -- $53,167 $0 -- $4,094,352 $0 -- $4,338,085 $0
Perspective Therapeutics, Inc. -- $42,241 $0 -- $42,241 $0 -- $359,010 $0
Greenwich Lifesciences, Inc. -- $38,502 $0 -- $149,158 $0 -- $515,477 $0
Fibrogen Inc -- $33,750 $0 -- $153,234 $0 -- $308,937 $0
Renovorx, Inc. -- $27,200 $0 -- $36,496 $0 -- $185,286 $0
Cocrystal Pharma, Inc. -- $22,787 $0 -- $22,787 $0 -- $22,787 $0
Lite Strategy, Inc. -- $22,777 $0 -- $22,777 $0 -- $22,777 $0
Salarius Pharmaceuticals, Inc. -- $19,740 $0 -- $19,740 $0 -- $19,740 $0
Zomedica Corp. -- $14,550 $0 -- $128,768 $0 -- $441,024 $0
Phio Pharmaceuticals Corp. -- $12,050 $0 -- $12,050 $0 -- $39,061 $0
Silo Pharma, Inc. -- $5,582 $0 -- $5,582 $0 -- $12,008 $0
Immix Biopharma, Inc. -- $4,976 $0 -- $25,217 $0 -- $129,575 $0
Iterum Therapeutics Plc -- $2,191 $0 -- $13,045 $0 -- $13,045 $0
Arvinas, Inc. -- $0 $0 3.49 $227,010 ($64,998) 0.25 $227,010 ($904,576)
Amphastar Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($63,877) 0.00 $0 ($130,930)
Aurinia Pharmaceuticals Inc. -- $0 $0 64.71 $13,590,000 ($210,000) 4.27 $26,303,126 ($6,156,646)
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($138,529) 0.00 $0 ($293,159)
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($151,622) 0.00 $0 ($885,909)
KALA BIO, Inc. -- $0 $0 0.00 $0 ($371,744) 0.00 $0 ($524,771)
Kezar Life Sciences, Inc. -- $0 $0 0.00 $0 ($3,531) 0.00 $0 ($3,531)
Regeneron Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($280,766) 0.00 $0 ($280,766)
Arcturus Therapeutics Holdings Inc. -- $0 $0 -- $20,499 $0 -- $20,499 $0
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($369,437) 0.00 $0 ($1,490,792)
Travere Therapeutics, Inc. -- $0 $0 0.00 $0 ($306,229) 0.00 $0 ($2,755,998)
Anixa Biosciences Inc -- $0 $0 -- $110,700 $0 -- $325,241 $0
Cumberland Pharmaceuticals Inc -- $0 $0 -- $19,381 $0 -- $48,606 $0
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($1,349,295) 0.00 $0 ($1,893,602)
Akero Therapeutics, Inc. -- $0 $0 0.00 $0 ($3,982,022) 1.10 $18,387,921 ($16,701,574)
Olema Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($204,841) 0.00 $0 ($1,174,859)
Hookipa Pharma Inc. -- $0 $0 0.00 $0 ($60,046) 0.00 $0 ($60,046)
Galectin Therapeutics Inc -- $0 $0 -- $17,420 $0 -- $52,303 $0
Tharimmune, Inc. -- $0 $0 -- $592,423 $0 -- $603,176 $0
Shattuck Labs, Inc. -- $0 $0 -- $10,943,653 $0 -- $10,943,653 $0
Bausch Health Companies Inc. -- $0 $0 1665.69 $365,820,183 ($219,621) 1683.03 $369,628,560 ($219,621)
Soleno Therapeutics Inc -- $0 $0 0.00 $0 ($316,971) 0.00 $0 ($2,269,296)
Uniqure N.V. -- $0 $0 0.00 $0 ($322,426) 0.00 $0 ($1,356,639)
89Bio, Inc. -- $0 $0 0.00 $0 ($115,280) 180.45 $50,099,844 ($277,638)
Ultragenyx Pharmaceutical Inc. -- $0 $0 0.00 $0 ($421,046) 0.00 $0 ($7,754,696)
Verona Pharma Plc -- $0 $0 0.00 $0 ($9,120,880) 0.00 $0 ($18,265,688)
Syndax Pharmaceuticals Inc -- $0 $0 0.00 $0 ($81,987) 0.58 $241,896 ($418,160)
Viridian Therapeutics, Inc.\De -- $0 $0 -- $9,999,990 $0 -- $9,999,990 $0
Abbvie Inc. -- $0 $0 0.00 $0 ($2,639,219) 0.00 $0 ($32,264,257)
Nuvectis Pharma, Inc. -- $0 $0 -- $168,110 $0 -- $189,035 $0
Karyopharm Therapeutics Inc. -- $0 $0 0.00 $0 ($21,174) 0.00 $0 ($197,184)
Alnylam Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($18,508,993) 0.00 $0 ($23,611,223)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($315,091) 0.00 $0 ($315,091)
Phathom Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($26,804) 1.55 $441,505 ($284,028)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,428,100) 0.00 $0 ($2,595,250)
Bristol Myers Squibb Co -- $0 $0 0.00 $0 ($2,650,480) 0.16 $412,284 ($2,654,167)
Vanda Pharmaceuticals Inc. -- $0 $0 1.29 $41,500 ($32,130) 15.99 $513,636 ($32,130)
Dynavax Technologies Corp -- $0 $0 -- $41,116 $0 0.06 $41,116 ($661,866)
Blueprint Medicines Corp -- $0 $0 0.00 $0 ($285,100) 0.00 $0 ($8,805,564)
Xencor Inc -- $0 $0 0.00 $0 ($132,464) 0.00 $0 ($726,467)
Evolus, Inc. -- $0 $0 0.15 $204,486 ($1,326,167) 0.10 $393,486 ($3,900,468)
Kalvista Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($992,221) 0.00 $0 ($992,221)
Cryoport, Inc. -- $0 $0 0.00 $0 ($118,348) 0.00 $0 ($331,589)
Immuneering Corp -- $0 $0 -- $486,700 $0 -- $486,700 $0
Viatris Inc -- $0 $0 3.05 $219,740 ($72,045) 10.49 $756,002 ($72,045)
Gossamer Bio, Inc. -- $0 $0 -- $50,016 $0 -- $50,016 $0
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($170,891) 0.00 $0 ($244,239)
Oric Pharmaceuticals, Inc. -- $0 $0 0.08 $262,899 ($3,450,144) 0.08 $262,899 ($3,482,406)
Tonix Pharmaceuticals Holding Corp. -- $0 $0 -- $24,061 $0 -- $110,261 $0
Igm Biosciences, Inc. -- $0 $0 0.00 $0 ($40,568) 0.00 $0 ($107,771)
Alzamend Neuro, Inc. -- $0 $0 0.00 $0 ($312,394) 0.07 $21,072 ($318,590)
CalciMedica, Inc. -- $0 $0 61.22 $223,467 ($3,650) 66.49 $242,702 ($3,650)
Relmada Therapeutics, Inc. -- $0 $0 -- $2,374,795 $0 -- $2,836,106 $0
Synlogic, Inc. -- $0 $0 0.00 $0 ($284) 0.00 $0 ($3,259)
Assertio Holdings, Inc. -- $0 $0 0.00 $0 ($6,806) 0.00 $0 ($6,806)
Nuvation Bio Inc. -- $0 $0 -- $1,103,906 $0 -- $2,091,111 $0
Disc Medicine, Inc. -- $0 $0 0.00 $0 ($20,002,370) 0.00 $0 ($61,695,050)
Schrodinger, Inc. -- $0 $0 0.00 $0 ($29,387) 0.00 $0 ($260,045)
Bespoke Extracts, Inc. -- $0 $0 -- $2,640 $0 -- $5,410 $0
Heron Therapeutics, Inc. /De/ -- $0 $0 -- $2,649,819 $0 -- $2,649,819 $0
Bicycle Therapeutics Plc -- $0 $0 0.00 $0 ($170,024) 26.44 $21,230,385 ($802,917)
Emergent Biosolutions Inc. -- $0 $0 0.00 $0 ($709,906) 0.34 $349,800 ($1,020,674)
Nkarta, Inc. -- $0 $0 0.00 $0 ($3,204) 0.00 $0 ($110,751)
Kiniksa Pharmaceuticals International, plc -- $0 $0 0.00 $0 ($124,397) 0.00 $0 ($494,872)
Aquestive Therapeutics, Inc. -- $0 $0 0.00 $0 ($907,995) 0.00 $0 ($907,995)
Anaptysbio, Inc -- $0 $0 0.00 $0 ($144,539) 7.61 $1,099,642 ($144,539)
Savara Inc -- $0 $0 -- $98,572 $0 1.84 $535,647 ($290,675)
Immunic, Inc. -- $0 $0 -- $16,694 $0 -- $246,928 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $124,750 $0 -- $133,150 $0
Mirum Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($155,091) 0.15 $280,117 ($1,911,152)
Macrogenics Inc -- $0 $0 -- $150,515 $0 -- $150,515 $0
Alx Oncology Holdings Inc -- $0 $0 45.32 $157,755 ($3,481) 5.02 $157,755 ($31,433)
Avidity Biosciences, Inc. -- $0 $0 0.00 $0 ($1,438,599) 0.00 $0 ($6,836,835)
Design Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,953,792) 0.00 $0 ($2,977,655)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($461,906) 0.00 $0 ($509,794)
Pmv Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($152,104) 0.00 $0 ($152,104)
Eton Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,178,031) 0.00 $0 ($4,770,642)
Supernus Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,605,335) 0.00 $0 ($2,605,335)
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,958) 0.00 $0 ($13,706)
Cogent Biosciences, Inc. -- $0 $0 -- $24,999,993 $0 -- $25,332,406 $0
Merck & Co., Inc. -- $0 $0 0.00 $0 ($1,336,435) 0.57 $1,577,424 ($2,772,787)
Summit Therapeutics Inc. -- $0 $0 -- $22,969,461 $0 -- $22,969,461 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 1.03 $228,343 ($221,004) 0.27 $310,319 ($1,140,979)
Soligenix, Inc. -- $0 $0 -- $20,000 $0 -- $20,000 $0
Viking Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,916,707) 0.00 $29,943 ($17,698,502)
Larimar Therapeutics, Inc. -- $0 $0 -- $30,000,000 $0 -- $30,000,000 $0
Xilio Therapeutics, Inc. -- $0 $0 -- $72,765 $0 -- $72,765 $0
Axsome Therapeutics, Inc. -- $0 $0 0.01 $200,466 ($13,373,843) 0.01 $200,466 ($14,479,691)
Ainos, Inc. -- $0 $0 0.00 $0 ($23,639) 0.00 $0 ($23,639)
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($111,726) 0.00 $0 ($347,113)
Aldeyra Therapeutics, Inc. -- $0 $0 0.12 $13,250 ($113,713) 0.12 $13,250 ($113,713)
Oncotelic Therapeutics, Inc. -- $0 $0 -- $994 $0 -- $10,705 $0
Skye Bioscience, Inc. -- $0 $0 0.00 $0 ($800,548) 0.00 $0 ($800,548)
Geovax Labs, Inc. -- $0 $0 -- $6,240 $0 -- $40,123 $0
Earth Science Tech, Inc. -- $0 $0 -- $48,349 $0 -- $295,969 $0
Aptevo Therapeutics Inc. -- $0 $0 -- $20,134 $0 -- $20,134 $0
Terns Pharmaceuticals, Inc. -- $0 $0 16.89 $186,595 ($11,047) 0.83 $186,595 ($224,504)
An2 Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,086) 0.75 $20,798 ($27,695)
Lexaria Bioscience Corp. -- $0 $0 -- $49,085 $0 -- $49,085 $0
Lyell Immunopharma, Inc. -- $0 $0 0.00 $0 ($147,804) 3.03 $447,931 ($147,804)
Rani Therapeutics Holdings, Inc. -- $0 $0 -- $1,260,417 $0 -- $1,290,410 $0
Benitec Biopharma Inc. -- $0 $0 -- $19,999,994 $0 -- $32,438,904 $0
Accustem Sciences Inc. -- $0 $0 -- $20,902 $0 -- $162,579 $0
Pepgen Inc. -- $0 $0 -- $30,000,000 $0 6049.27 $30,071,668 ($4,971)
Carisma Therapeutics Inc. -- $0 $0 0.00 $0 ($124,343) 0.00 $0 ($124,343)
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 0.02 $9,640 ($615,000) 0.02 $9,640 ($615,000)
Akari Therapeutics Plc -- $0 $0 -- $56,660 $0 -- $56,660 $0
Quoin Pharmaceuticals, Ltd. -- $0 $0 -- $128,640 $0 -- $728,640 $0
NewAmsterdam Pharma Co N.V. -- $0 $0 0.09 $295,267 ($3,130,659) 0.13 $404,991 ($3,130,659)
Cadrenal Therapeutics, Inc. -- $0 $0 0.00 $0 ($640,578) 0.00 $0 ($640,578)
JUPITER NEUROSCIENCES, INC. -- $0 $0 -- $4,439 $0 -- $4,439 $0
BullFrog AI Holdings, Inc. -- $0 $0 0.00 $0 ($76,536) 0.00 $0 ($150,630)
Mural Oncology plc -- $0 $0 0.00 $0 ($67,620) 0.00 $0 ($160,463)
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $1,499,988 $0 -- $1,499,988 $0
Zenas Biopharma, Inc. -- $0 $0 -- $15,228,178 $0 -- $15,472,528 $0
Mbx Biosciences, Inc. -- $0 $0 -- $12,537,762 $0 -- $17,159,085 $0
Camp4 Therapeutics Corp -- $0 $0 -- $2,054,995 $0 -- $2,054,995 $0
Septerna, Inc. -- $0 $0 0.00 $0 ($63,223) 14.78 $934,328 ($63,223)
Aardvark Therapeutics, Inc. -- $0 $0 -- $305,717 $0 -- $305,717 $0
Processa Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $9,889 $0
Avid Bioservices, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,785,375)
Zentalis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 3.86 $252,786 ($65,472)
Y-Mabs Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($76,905)
2Seventy Bio, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($432,992)
Clearside Biomedical, Inc. -- $0 $0 -- $0 $0 -- $13,800 $0
Biomarin Pharmaceutical Inc -- $0 $0 -- $0 $0 0.00 $0 ($809,527)
LIFECORE BIOMEDICAL, INC. \DE\ -- $0 $0 -- $0 $0 -- $97,580 $0
Repare Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($42,488)
Regulus Therapeutics Inc. -- $0 $0 -- $0 $0 0.55 $170,899 ($310,669)
Bolt Biotherapeutics, Inc. -- $0 $0 -- $0 $0 -- $3,856 $0
Checkpoint Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,598,055)
Chimerix Inc -- $0 $0 -- $0 $0 0.00 $0 ($91,140)
Rhythm Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,948,121)
GYRE THERAPEUTICS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,546,917)
Zoetis Inc. -- $0 $0 -- $0 $0 0.00 $0 ($367,289)
Aprea Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $10,110 $0
Tvardi Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,301)
Altimmune, Inc. -- $0 $0 -- $0 $0 -- $57,780 $0
Elanco Animal Health Inc -- $0 $0 -- $0 $0 -- $483,558 $0
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($160,802)
Generation Bio Co. -- $0 $0 -- $0 $0 -- $203,209 $0
Ibio, Inc. -- $0 $0 -- $0 $0 -- $654,995 $0
Optinose, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($58,362)
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($94,797)
Assembly Biosciences, Inc. -- $0 $0 -- $0 $0 3.41 $49,998 ($14,664)
Longeveron Inc. -- $0 $0 -- $0 $0 0.00 $0 ($36,757)
Alaunos Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,022)
Cue Biopharma, Inc. -- $0 $0 -- $0 $0 -- $30,900 $0
Neurogene Inc. -- $0 $0 -- $0 $0 0.00 $0 ($179,250)
Arbutus Biopharma Corp -- $0 $0 -- $0 $0 0.00 $0 ($251,655)
Veru Inc. -- $0 $0 -- $0 $0 -- $84,351 $0
MARINUS PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,733)
Vyne Therapeutics Inc. -- $0 $0 -- $0 $0 -- $43,800 $0
Marker Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $35,472 $0
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,501,298)
Prelude Therapeutics Inc -- $0 $0 -- $0 $0 -- $876,166 $0
Pfizer Inc -- $0 $0 -- $0 $0 7.70 $499,072 ($64,825)
Therapeuticsmd, Inc. -- $0 $0 -- $0 $0 -- $2,809 $0
Immunome Inc. -- $0 $0 -- $0 $0 -- $2,430,579 $0
Kronos Bio, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($21,554)
Janux Therapeutics, Inc. -- $0 $0 -- $0 $0 10.40 $25,342,965 ($2,436,594)
Pds Biotechnology Corp -- $0 $0 -- $0 $0 -- $50,001 $0
Atai Life Sciences N.V. -- $0 $0 -- $0 $0 0.00 $0 ($246,038)
Palatin Technologies Inc -- $0 $0 -- $0 $0 -- $10,180 $0
Jade Biosciences, Inc. -- $0 $0 -- $0 $0 -- $44,400 $0
Atossa Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $16,887 $0
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 0.97 $4,971 ($5,141)
Hcw Biologics Inc. -- $0 $0 -- $0 $0 -- $3,045,056 $0
PALVELLA THERAPEUTICS, INC. -- $0 $0 -- $0 $0 -- $152,517 $0
Opus Genetics, Inc. -- $0 $0 -- $0 $0 -- $97,600 $0
Acurx Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $170,000 $0
Ventyx Biosciences, Inc. -- $0 $0 -- $0 $0 5.80 $300,573 ($51,860)
Context Therapeutics Inc. -- $0 $0 -- $0 $0 -- $107,086 $0
Nrx Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $46,800 $0
Io Biotech, Inc. -- $0 $0 -- $0 $0 -- $75,761 $0
Atea Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $81,498 $0
Geron Corp -- $0 $0 -- $0 $0 -- $221,880 $0
AYTU BIOPHARMA, INC -- $0 $0 -- $0 $0 -- $144,498 $0
Unity Biotechnology, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($145,017)
TALPHERA, INC. -- $0 $0 -- $0 $0 -- $125,000 $0
Avadel Pharmaceuticals Plc -- $0 $0 -- $0 $0 -- $431,759 $0
Tango Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($143,227)
Rigel Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($424,179)
Promis Neurosciences Inc. -- $0 $0 -- $0 $0 -- $14,595 $0
Rafael Holdings, Inc. -- $0 $0 -- $0 $0 -- $16,742,985 $0
Anebulo Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $10,000,000 $0
Journey Medical Corp -- $0 $0 -- $0 $0 0.00 $0 ($887,229)
Zymeworks Inc. -- $0 $0 -- $0 $0 -- $58,036,053 $0
Aspire Biopharma Holdings, Inc. -- $0 $0 -- $0 $0 1.00 $7,800 ($7,800)
AEON Biopharma, Inc. -- $0 $0 -- $0 $0 -- $84,550 $0
Serina Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $17,745 $0
MetaVia Inc. -- $0 $0 -- $0 $0 -- $9,940 $0
Entero Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($465)
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 -- $35,810 $0
ACELYRIN, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($68,902)
FibroBiologics, Inc. -- $0 $0 -- $0 $0 -- $16,800 $0
Nika Pharmaceuticals, Inc -- $0 $0 -- $0 $0 0.00 $0 ($500,000)
IMPACT BIOMEDICAL INC. -- $0 $0 -- $0 $0 0.00 $0 ($4,209,761)
Apimeds Pharmaceuticals US, Inc. -- $0 $0 -- $0 $0 -- $107,074 $0