Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 9/14/2026 10:02:20 PM
1 Month
Buy/Sell Ratio 0.20
16%
84%
Buy Sell
$25.36 M ($127.51) M
46 Insiders 136 Insiders
79 Transactions 185 Transactions
8/14/2026 to 9/14/2026
3 Month
Buy/Sell Ratio 0.15
12%
88%
Buy Sell
$111.69 M ($750.20) M
121 Insiders 345 Insiders
215 Transactions 596 Transactions
6/14/2026 to 9/14/2026
6 Month
Buy/Sell Ratio 0.30
23%
77%
Buy Sell
$403.64 M ($1,327.49) M
213 Insiders 558 Insiders
422 Transactions 1311 Transactions
3/14/2026 to 9/14/2026
12 Month
Buy/Sell Ratio 0.29
22%
78%
Buy Sell
$732.10 M ($2,568.58) M
382 Insiders 880 Insiders
864 Transactions 2807 Transactions
9/14/2025 to 9/14/2026

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Wave Life Sciences Ltd.
$54,631,065 4
Summit Therapeutics Inc.
$51,947,183 3
Summit Therapeutics Inc.
$51,947,183 3
CRESCENT BIOPHARMA, INC.
$30,612,625 2
Pepgen Inc.
$30,000,000 1
Viridian Therapeutics, Inc.\De
$29,999,980 2
ALUMIS INC.
$28,768,847 17
Aurinia Pharmaceuticals Inc.
$25,144,033 6
Larimar Therapeutics, Inc.
$25,000,000 4
Biohaven Ltd.
$24,999,998 1

Most Insider Selling

12 months
Name Value Transactions
Roivant Sciences Ltd.
($154,472,307) 10
Roivant Sciences Ltd.
($147,382,307) 9
BeOne Medicines Ltd.
($129,947,766) 10
Dyne Therapeutics, Inc.
($129,095,797) 19
Cogent Biosciences, Inc.
($127,400,000) 1
Liquidia Corp
($118,662,602) 19
Septerna, Inc.
($63,452,500) 1
MoonLake Immunotherapeutics
($62,962,500) 1
Bridgebio Pharma, Inc.
($58,606,958) 41
Sionna Therapeutics, Inc.
($55,674,636) 20

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Elanco Animal Health Inc 7 11
Indivior Pharmaceuticals, Inc. 7 8
Zenas Biopharma, Inc. 6 21
CervoMed Inc. 5 12
Hepion Pharmaceuticals, Inc. 5 11
Maia Biotechnology, Inc. 5 9
HYPERION DEFI, INC. 5 8
Braveheart Bio, Inc. 5 5
Quoin Pharmaceuticals, Ltd. 5 5
Relmada Therapeutics, Inc. 4 10

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
TAKEDA PHARMACEUTICAL CO LTD 13 18
Vertex Pharmaceuticals Inc / Ma 12 53
Ani Pharmaceuticals Inc 12 42
Ionis Pharmaceuticals Inc 12 31
BeOne Medicines Ltd. 11 36
Uniqure N.V. 11 17
Arrowhead Pharmaceuticals, Inc. 10 21
Liquidia Corp 9 59
Ptc Therapeutics, Inc. 9 45
Insmed Inc 9 39

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Kura Oncology, Inc. 5.23 $2,351,000 ($449,344) 1.63 $2,351,000 ($1,438,392) 0.80 $2,351,000 ($2,940,242)
Keros Therapeutics, Inc. 0.10 $10,270 ($101,136) 0.28 $53,350 ($191,130) 0.14 $75,770 ($522,950)
An2 Therapeutics, Inc. 0.04 $11,602 ($318,205) 0.03 $11,602 ($344,181) 0.03 $11,602 ($398,298)
Precigen, Inc. 0.02 $24,662 ($1,376,400) 0.00 $24,662 ($20,218,036) 0.00 $92,957 ($48,082,990)
Camp4 Therapeutics Corp 0.02 $39,600 ($2,504,037) 0.04 $99,051 ($2,504,037) 0.04 $99,051 ($2,504,037)
BELITE BIO, INC 0.00 $0 ($31,886,076) 0.00 $0 ($40,542,885) 0.00 $0 ($40,542,885)
Corcept Therapeutics Inc 0.00 $0 ($13,413,983) 0.15 $3,313,809 ($22,645,529) 0.10 $3,313,809 ($32,950,837)
Eli Lilly & Co 0.00 $0 ($7,638,150) 0.00 $0 ($18,835,095) 0.00 $0 ($19,845,595)
Madrigal Pharmaceuticals, Inc. 0.00 $0 ($6,581,138) 0.00 $0 ($10,461,835) 0.00 $0 ($17,158,081)
Eton Pharmaceuticals, Inc. 0.00 $0 ($6,087,773) 0.00 $0 ($9,913,490) 0.00 $0 ($9,913,490)
Royalty Pharma Plc 0.00 $0 ($5,997,250) 0.00 $0 ($33,240,887) 0.00 $0 ($86,496,019)
Ptc Therapeutics, Inc. 0.00 $0 ($4,963,724) 0.00 $0 ($10,716,043) 0.00 $0 ($17,807,429)
Disc Medicine, Inc. 0.00 $0 ($4,502,997) 0.00 $0 ($5,344,280) 0.00 $0 ($23,964,112)
Rapport Therapeutics, Inc. 0.00 $0 ($3,864,197) 0.00 $0 ($9,564,511) 0.00 $0 ($14,524,578)
Insmed Inc 0.00 $0 ($3,737,650) 0.00 $0 ($12,921,016) 0.00 $0 ($39,778,676)
Bridgebio Pharma, Inc. 0.00 $0 ($3,727,251) 0.00 $0 ($23,505,784) 0.00 $0 ($81,891,482)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($2,944,962) 0.01 $51,338 ($3,483,830) 0.02 $152,183 ($6,868,137)
Urogen Pharma Ltd. 0.00 $0 ($2,854,853) 0.00 $0 ($3,904,953) 0.00 $0 ($4,300,127)
TAKEDA PHARMACEUTICAL CO LTD 0.00 $0 ($2,746,837) 0.00 $0 ($12,448,308) 0.00 $0 ($12,448,308)
Jazz Pharmaceuticals Plc 0.00 $0 ($2,275,968) 0.00 $0 ($10,319,789) 0.00 $0 ($19,761,211)
Regeneron Pharmaceuticals, Inc. 0.00 $0 ($2,002,458) 0.00 $0 ($2,280,739) 0.00 $0 ($2,717,908)
Ligand Pharmaceuticals Inc 0.00 $0 ($1,772,434) 0.00 $0 ($4,476,521) 0.00 $0 ($7,062,452)
KAMADA LTD 0.00 $0 ($1,463,734) 0.00 $0 ($1,463,734) 0.00 $0 ($1,463,734)
Spyre Therapeutics, Inc. 0.00 $0 ($1,309,410) 0.00 $0 ($14,876,417) 0.00 $0 ($17,946,596)
Arrowhead Pharmaceuticals, Inc. 0.00 $0 ($1,186,600) 0.00 $0 ($3,099,219) 0.00 $0 ($34,468,522)
Biomarin Pharmaceutical Inc 0.00 $0 ($1,163,748) 0.00 $0 ($1,340,430) 0.00 $0 ($4,318,214)
Evolus, Inc. 0.00 $0 ($950,019) 0.00 $0 ($1,029,763) 0.00 $0 ($1,121,292)
Ani Pharmaceuticals Inc 0.00 $0 ($715,625) 0.00 $0 ($7,440,408) 0.00 $0 ($13,483,267)
Teva Pharmaceutical Industries Ltd 0.00 $0 ($695,750) 0.00 $0 ($19,222,571) 0.00 $0 ($40,746,699)
Aurinia Pharmaceuticals Inc. 0.00 $0 ($546,373) 22.80 $12,455,227 ($546,373) 46.02 $25,144,033 ($546,373)
Korro Bio, Inc. 0.00 $0 ($502,176) 0.00 $0 ($5,012,671) 0.00 $0 ($5,012,671)
Ardelyx, Inc. 0.00 $0 ($486,197) 0.00 $0 ($1,027,139) 0.98 $1,946,331 ($1,988,178)
Alkermes Plc. 0.00 $0 ($470,589) 0.00 $0 ($994,906) 0.00 $0 ($1,726,021)
Bristol Myers Squibb Co 0.00 $0 ($437,248) 0.00 $0 ($2,287,264) 0.00 $0 ($2,287,264)
Cytokinetics Inc 0.00 $0 ($432,060) 0.00 $0 ($11,441,948) 0.00 $0 ($15,055,815)
Xenon Pharmaceuticals Inc. 0.00 $0 ($425,829) 0.00 $0 ($1,199,867) 0.00 $0 ($2,346,746)
Aardvark Therapeutics, Inc. 0.00 $0 ($394,957) 0.00 $0 ($394,957) 0.61 $241,219 ($394,957)
Enliven Therapeutics, Inc. 0.00 $0 ($352,551) 0.00 $0 ($1,202,806) 0.00 $0 ($9,481,778)
Ocular Therapeutix, Inc 0.00 $0 ($333,081) 0.00 $0 ($693,500) 0.13 $461,354 ($3,421,542)
Xeris Biopharma Holdings, Inc. 0.00 $0 ($311,242) 0.00 $0 ($2,614,012) 0.00 $0 ($4,409,531)
Arcutis Biotherapeutics, Inc. 0.00 $0 ($295,805) 0.00 $0 ($1,319,688) 0.00 $0 ($11,306,357)
Q32 Bio Inc. 0.00 $0 ($275,144) 109.03 $30,000,000 ($275,144) 65.24 $30,000,000 ($459,828)
Tg Therapeutics, Inc. 0.00 $0 ($274,800) 0.00 $0 ($274,800) 0.00 $0 ($437,650)
Bausch Health Companies Inc. 0.00 $0 ($258,894) 0.00 $0 ($391,690) 0.00 $0 ($506,730)
Dyne Therapeutics, Inc. 0.00 $0 ($247,777) 0.00 $190,960 ($152,804,488) 0.00 $274,840 ($168,617,119)
Lyell Immunopharma, Inc. 0.00 $0 ($193,374) 0.00 $0 ($251,600) 0.00 $0 ($604,312)
Stoke Therapeutics, Inc. 0.00 $0 ($170,061) 0.00 $0 ($1,712,014) 0.00 $0 ($7,542,618)
Adlai Nortye Ltd. 0.00 $0 ($164,635) 0.00 $0 ($164,767) 0.00 $0 ($164,767)
BeOne Medicines Ltd. 0.00 $0 ($153,374) 0.00 $0 ($94,809,495) 0.00 $0 ($141,889,731)
GENELUX CORP 0.00 $0 ($146,670) 0.00 $0 ($251,802) 0.00 $0 ($368,042)
Skye Bioscience, Inc. 0.00 $0 ($140,313) 0.00 $0 ($140,313) 0.00 $0 ($140,313)
Macrogenics Inc 0.00 $0 ($129,086) 0.00 $0 ($129,086) 0.00 $0 ($129,086)
Mannkind Corp 0.00 $0 ($127,856) 0.00 $0 ($352,114) 0.00 $0 ($995,090)
Opus Genetics, Inc. 0.00 $0 ($127,212) 0.00 $0 ($7,991,107) 0.02 $323,693 ($16,591,107)
Aquestive Therapeutics, Inc. 0.00 $0 ($107,168) 0.00 $0 ($346,783) 0.00 $0 ($2,826,492)
Abeona Therapeutics Inc. 0.00 $0 ($87,966) 0.00 $0 ($2,111,431) 0.00 $0 ($3,698,578)
NovaBridge Biosciences 0.00 $0 ($79,904) 4.71 $577,300 ($122,488) 4.71 $577,300 ($122,488)
Amphastar Pharmaceuticals, Inc. 0.00 $0 ($75,306) 0.00 $0 ($237,158) 0.00 $0 ($370,902)
Pacira Biosciences, Inc. 0.00 $0 ($70,619) 0.00 $0 ($528,111) 0.00 $0 ($1,277,179)
Mirum Pharmaceuticals, Inc. 0.00 $0 ($65,800) 0.00 $0 ($2,061,295) 2.75 $8,999,984 ($3,273,974)
Ascendis Pharma A/S 0.00 $0 ($62,335) 0.17 $777,066 ($4,703,356) 0.17 $777,066 ($4,703,356)
Lifevantage Corp 0.00 $0 ($55,649) 0.08 $11,577 ($141,108) 0.41 $194,798 ($471,625)
Nektar Therapeutics 0.00 $0 ($43,476) 0.00 $0 ($2,034,537) 0.00 $0 ($2,433,286)
Travere Therapeutics, Inc. 0.00 $0 ($42,610) 0.00 $0 ($4,167,030) 0.00 $0 ($10,050,730)
NewAmsterdam Pharma Co N.V. 0.00 $0 ($40,512) 0.00 $0 ($40,512) 0.00 $15,639 ($3,461,426)
Acrivon Therapeutics, Inc. 0.00 $0 ($37,005) 0.00 $0 ($39,806) 2.87 $114,341 ($39,806)
CYPHERPUNK TECHNOLOGIES INC. 0.00 $0 ($34,400) 0.00 $0 ($77,030) 0.00 $0 ($5,146,491)
Liquidia Corp 0.00 $0 ($18,566) 0.00 $0 ($159,723,256) 0.00 $0 ($164,522,387)
Generate Biomedicines, Inc. 0.00 $0 ($16,002) 0.00 $0 ($16,002) 18.80 $300,800 ($16,002)
Rocket Pharmaceuticals, Inc. 0.00 $0 ($9,886) 0.00 $0 ($279,197) 0.06 $34,400 ($550,281)
Imunon, Inc. 0.00 $0 ($7,942) 0.00 $0 ($38,153) 0.00 $0 ($38,153)
Zai Lab Ltd 0.00 $0 ($7,020) 0.10 $65,804 ($647,925) 0.04 $65,804 ($1,550,156)
Chemomab Therapeutics Ltd. 0.00 $0 ($6,516) 3.11 $20,246 ($6,516) 3.11 $20,246 ($6,516)
Alx Oncology Holdings Inc 0.00 $0 ($5,410) 0.00 $0 ($36,948) 119.74 $5,099,352 ($42,588)
Alzamend Neuro, Inc. 0.00 $0 ($3,116) 106.16 $330,827 ($3,116) 1.67 $330,827 ($198,224)
Abbott Laboratories 0.00 $0 ($2,958) 2.02 $1,301,477 ($645,463) 3.30 $4,402,775 ($1,333,826)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($2,252) 0.00 $0 ($897,309) 0.00 $0 ($3,936,661)
Karyopharm Therapeutics Inc. 0.00 $0 ($38) 0.00 $0 ($40,136) 0.00 $0 ($368,615)
ALUMIS INC. -- $9,699,359 $0 24.60 $9,699,359 ($394,311) 99.91 $39,396,484 ($394,311)
CYBIN INC. -- $8,284,382 $0 -- $8,284,382 $0 -- $8,284,382 $0
Relmada Therapeutics, Inc. -- $1,671,990 $0 -- $1,671,990 $0 -- $4,030,050 $0
Elanco Animal Health Inc -- $1,030,193 $0 -- $1,672,850 $0 -- $2,610,757 $0
Abcellera Biologics Inc. -- $680,742 $0 -- $1,641,080 $0 -- $1,965,232 $0
NEONC TECHNOLOGIES HOLDINGS, INC. -- $288,593 $0 -- $1,070,516 $0 -- $1,262,535 $0
Quoin Pharmaceuticals, Ltd. -- $279,966 $0 -- $279,966 $0 -- $408,606 $0
Maia Biotechnology, Inc. -- $252,307 $0 -- $456,083 $0 -- $910,874 $0
Grace Therapeutics, Inc. -- $214,000 $0 -- $214,000 $0 -- $214,000 $0
Verrica Pharmaceuticals Inc. -- $109,690 $0 -- $210,890 $0 -- $18,183,588 $0
Veraxa Biotech Holding AG -- $82,650 $0 -- $82,650 $0 -- $82,650 $0
Indivior Pharmaceuticals, Inc. -- $53,535 $0 0.04 $107,955 ($2,829,211) 0.11 $311,563 ($2,829,211)
Anixa Biosciences Inc -- $49,350 $0 -- $249,135 $0 -- $279,535 $0
Biovie Inc. -- $49,118 $0 -- $49,118 $0 -- $49,118 $0
Tonix Pharmaceuticals Holding Corp. -- $40,180 $0 -- $458,758 $0 -- $458,758 $0
Phio Pharmaceuticals Corp. -- $27,700 $0 -- $37,600 $0 -- $59,900 $0
ALTERITY THERAPEUTICS LTD -- $23,810 $0 -- $23,810 $0 -- $23,810 $0
Protagenic Therapeutics, Inc.\New -- $23,756 $0 -- $30,717 $0 -- $30,717 $0
Telix Pharmaceuticals Ltd -- $19,998 $0 -- $1,016,736 $0 -- $1,016,736 $0
Tyra Biosciences, Inc. -- $19,982 $0 -- $19,982 $0 0.00 $19,982 ($10,061,326)
Emmaus Life Sciences, Inc. -- $15,026 $0 -- $15,026 $0 -- $15,026 $0
ELITE PHARMACEUTICALS INC /NV/ -- $8,610 $0 -- $8,610 $0 0.02 $8,610 ($499,200)
Ctt Pharmaceutical Holdings, Inc. -- $2,195 $0 -- $2,808 $0 -- $14,609 $0
Faeth Therapeutics, Inc. -- $0 $0 -- $1,133,317 $0 -- $1,133,317 $0
Arvinas, Inc. -- $0 $0 0.00 $0 ($589,509) 0.35 $495,080 ($1,421,163)
Greenwich Lifesciences, Inc. -- $0 $0 -- $97,003 $0 -- $586,328 $0
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($910,095) 0.00 $0 ($1,352,437)
Processa Pharmaceuticals, Inc. -- $0 $0 -- $208,638 $0 -- $208,638 $0
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($1,084,258) 0.00 $0 ($1,503,247)
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($62,181) 0.09 $86,588 ($962,955)
Verastem, Inc. -- $0 $0 0.00 $0 ($116,585) 0.00 $0 ($738,229)
Prothena Corp Public Ltd Co -- $0 $0 0.00 $0 ($135,975) 0.00 $0 ($135,975)
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,954,678) 0.00 $0 ($2,700,753)
United Therapeutics Corp -- $0 $0 0.00 $0 ($1,251,183) 0.00 $0 ($2,463,385)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($412,305) 0.00 $0 ($1,166,016)
Tempest Therapeutics, Inc. -- $0 $0 -- $1,000,002 $0 -- $1,000,002 $0
Olema Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($291,162) 0.00 $0 ($5,482,196)
Entrada Therapeutics, Inc. -- $0 $0 0.01 $29,316 ($2,317,150) 0.01 $29,316 ($4,674,123)
Canton Strategic Holdings, Inc. -- $0 $0 0.00 $0 ($343,882) 0.00 $0 ($343,882)
Shattuck Labs, Inc. -- $0 $0 0.61 $250,000 ($408,600) 0.61 $250,000 ($408,600)
Soleno Therapeutics Inc -- $0 $0 0.00 $0 ($429,344) 0.00 $0 ($429,344)
Uniqure N.V. -- $0 $0 0.00 $0 ($966,917) 0.00 $0 ($2,258,860)
Vertex Pharmaceuticals Inc / Ma -- $0 $0 0.00 $0 ($12,495,241) 0.00 $0 ($65,561,533)
Syndax Pharmaceuticals Inc -- $0 $0 0.00 $0 ($152,376) 0.00 $0 ($780,667)
Viridian Therapeutics, Inc.\De -- $0 $0 -- $19,999,990 $0 423.76 $29,999,980 ($70,796)
Nuvectis Pharma, Inc. -- $0 $0 -- $250,000 $0 -- $418,110 $0
HYPERION DEFI, INC. -- $0 $0 -- $29,580 $0 -- $641,038 $0
Alnylam Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,274,343) 0.00 $0 ($33,971,878)
Vera Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,011,051) 0.10 $249,985 ($2,524,590)
Rhythm Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($912,703) 0.00 $0 ($3,129,837)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($914,400) 0.00 $0 ($1,066,655)
GYRE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($82,927) 0.00 $0 ($82,927)
Zoetis Inc. -- $0 $0 -- $886,367 $0 -- $886,367 $0
Nuvalent, Inc. -- $0 $0 0.00 $0 ($261,363) 0.00 $0 ($49,326,257)
Wave Life Sciences Ltd. -- $0 $0 587.35 $54,624,378 ($93,002) 57.68 $54,631,065 ($947,139)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($33,550) 0.00 $0 ($33,550)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($650,641) 0.00 $0 ($4,285,614)
Altimmune, Inc. -- $0 $0 -- $154,199 $0 -- $370,038 $0
Theravance Biopharma, Inc. -- $0 $0 0.00 $0 ($651,804) 0.00 $0 ($2,633,575)
Ironwood Pharmaceuticals Inc -- $0 $0 0.00 $0 ($21,188,971) 0.00 $0 ($22,497,443)
Xencor Inc -- $0 $0 0.00 $0 ($422,125) 0.00 $0 ($950,090)
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 0.35 $126,255 ($365,473) 0.21 $126,255 ($612,981)
Roivant Sciences Ltd. -- $0 $0 0.00 $0 ($115,832,608) 0.00 $49,957 ($311,889,071)
CRESCENT BIOPHARMA, INC. -- $0 $0 10.09 $12,375,025 ($1,226,126) 24.97 $30,612,625 ($1,226,126)
Cryoport, Inc. -- $0 $0 0.00 $0 ($6,785,511) 0.00 $0 ($6,901,051)
Ibio, Inc. -- $0 $0 -- $98,106 $0 -- $98,106 $0
Immuneering Corp -- $0 $0 -- $35,993 $0 -- $422,978 $0
Viatris Inc -- $0 $0 0.00 $0 ($1,093,323) 0.00 $0 ($1,093,323)
Johnson & Johnson -- $0 $0 0.00 $0 ($12,515,010) 0.01 $257,688 ($34,962,666)
Arcus Biosciences, Inc. -- $0 $0 0.00 $0 ($3,174,409) 0.00 $0 ($12,572,842)
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($342,716) 0.00 $0 ($695,474)
Oramed Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($330,744) 0.00 $0 ($330,744)
Oric Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,600) 0.00 $0 ($2,949,043)
Assembly Biosciences, Inc. -- $0 $0 0.00 $0 ($14,687) 0.00 $0 ($14,687)
Oruka Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,939,015) 0.00 $0 ($2,939,015)
CalciMedica, Inc. -- $0 $0 -- $199,999 $0 -- $216,779 $0
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($65,614) 0.00 $0 ($599,654)
Ionis Pharmaceuticals Inc -- $0 $0 0.25 $1,058,700 ($4,229,345) 0.04 $1,058,700 ($25,328,906)
Nuvation Bio Inc. -- $0 $0 -- $118,250 $0 -- $118,250 $0
Annexon, Inc. -- $0 $0 -- $3,414,859 $0 39.30 $12,318,919 ($313,428)
Lipocine Inc. -- $0 $0 -- $434,600 $0 -- $434,600 $0
Schrodinger, Inc. -- $0 $0 0.00 $0 ($24,406) 0.00 $0 ($346,988)
Avalo Therapeutics, Inc. -- $0 $0 0.00 $0 ($617,656) 0.00 $0 ($617,656)
Bicycle Therapeutics Plc -- $0 $0 0.00 $0 ($130,437) 0.00 $0 ($551,656)
KYNTRA BIO, INC. -- $0 $0 -- $19,852 $0 -- $53,602 $0
Emergent Biosolutions Inc. -- $0 $0 0.00 $0 ($577,200) 0.00 $0 ($1,156,423)
Protagonist Therapeutics, Inc -- $0 $0 0.00 $0 ($184,572) 0.00 $0 ($5,004,968)
Nkarta, Inc. -- $0 $0 0.00 $0 ($4,813) 0.00 $0 ($70,422)
Kiniksa Pharmaceuticals International, plc -- $0 $0 0.00 $0 ($687,927) 0.00 $0 ($1,190,607)
Zomedica Corp. -- $0 $0 -- $146,903 $0 -- $193,929 $0
Neurogene Inc. -- $0 $0 0.00 $0 ($787,444) 0.00 $0 ($1,133,592)
Phibro Animal Health Corp -- $0 $0 0.05 $317,700 ($6,432,668) 0.02 $317,700 ($19,780,721)
Anaptysbio, Inc -- $0 $0 0.00 $0 ($2,247,650) 0.00 $0 ($2,440,993)
Hepion Pharmaceuticals, Inc. -- $0 $0 -- $1,225,000 $0 -- $1,225,000 $0
Lite Strategy, Inc. -- $0 $0 -- $21,388 $0 -- $141,864 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $49,997 $0 68.30 $49,997 ($732)
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($120,444) 0.00 $0 ($424,424)
Veru Inc. -- $0 $0 -- $4,842 $0 -- $4,842 $0
Amneal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($7,667,124) 0.00 $0 ($8,253,124)
Edgewise Therapeutics, Inc. -- $0 $0 0.00 $0 ($506,735) 0.39 $199,403 ($506,735)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,232,151) 0.00 $0 ($1,694,057)
Genprex, Inc. -- $0 $0 0.00 $0 ($22) 0.00 $0 ($22)
Prelude Therapeutics Inc -- $0 $0 -- $24,999,997 $0 -- $24,999,997 $0
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($3,319) 0.00 $0 ($5,499)
Werewolf Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,177,507) 0.00 $0 ($3,255,559)
Corvus Pharmaceuticals, Inc. -- $0 $0 -- $333,689 $0 -- $333,689 $0
Cocrystal Pharma, Inc. -- $0 $0 -- $80,406 $0 -- $300,212 $0
Pfizer Inc -- $0 $0 21.98 $2,960,110 ($134,661) 21.98 $2,960,110 ($134,661)
Merck & Co., Inc. -- $0 $0 0.00 $0 ($10,046,142) 0.00 $0 ($29,406,103)
Summit Therapeutics Inc. -- $0 $0 -- $103,616,650 $0 -- $114,616,599 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($495,047) 0.00 $0 ($619,095)
CervoMed Inc. -- $0 $0 -- $3,000,000 $0 -- $3,737,723 $0
Immunome Inc. -- $0 $0 0.05 $604,102 ($11,484,773) 0.11 $2,101,730 ($19,814,853)
Opko Health, Inc. -- $0 $0 -- $11,350 $0 -- $3,202,941 $0
Equillium, Inc. -- $0 $0 0.00 $0 ($723,830) 0.00 $0 ($787,440)
Viking Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,267,665) 0.01 $149,912 ($21,690,334)
Janux Therapeutics, Inc. -- $0 $0 0.00 $0 ($85,822) 0.00 $0 ($347,145)
Larimar Therapeutics, Inc. -- $0 $0 -- $166,890 $0 -- $25,716,890 $0
Hcw Biologics Inc. -- $0 $0 -- $529,993 $0 -- $529,993 $0
Rezolute, Inc. -- $0 $0 -- $28,500 $0 -- $284,397 $0
Organon & Co. -- $0 $0 0.00 $0 ($553,382) 0.91 $501,755 ($553,382)
Annovis Bio, Inc. -- $0 $0 -- $1,641,759 $0 -- $4,456,876 $0
PALVELLA THERAPEUTICS, INC. -- $0 $0 -- $49,974 $0 -- $849,974 $0
Xilio Therapeutics, Inc. -- $0 $0 -- $43,950 $0 -- $43,950 $0
Axsome Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,161,126) 0.00 $0 ($8,188,876)
Cns Pharmaceuticals, Inc. -- $0 $0 -- $44,002 $0 -- $44,002 $0
Dermata Therapeutics, Inc. -- $0 $0 0.00 $0 ($13) 97.01 $1,270 ($13)
Atea Pharmaceuticals, Inc. -- $0 $0 -- $25,446 $0 -- $25,446 $0
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($63,352) 0.00 $0 ($552,042)
Aldeyra Therapeutics, Inc. -- $0 $0 -- $523,550 $0 -- $523,550 $0
Oncotelic Therapeutics, Inc. -- $0 $0 -- $37,832 $0 -- $37,832 $0
Natures Sunshine Products Inc -- $0 $0 0.00 $0 ($742,411) 0.00 $0 ($2,094,604)
Rein Therapeutics, Inc. -- $0 $0 -- $74,561 $0 -- $74,561 $0
Lantern Pharma Inc. -- $0 $0 -- $200,001 $0 -- $200,001 $0
Milestone Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($82,490) 0.00 $0 ($180,365)
MoonLake Immunotherapeutics -- $0 $0 0.00 $0 ($77,039,456) 0.00 $98,808 ($83,026,619)
Maravai Lifesciences Holdings, Inc. -- $0 $0 0.00 $0 ($254,000) 7.40 $1,880,244 ($254,000)
Renovorx, Inc. -- $0 $0 -- $19,690 $0 -- $84,427 $0
Ensysce Biosciences, Inc. -- $0 $0 -- $444,169 $0 -- $444,169 $0
Terns Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($49,693) 0.00 $0 ($101,652)
Rigel Pharmaceuticals Inc -- $0 $0 0.00 $0 ($160,425) 0.00 $0 ($160,425)
Promis Neurosciences Inc. -- $0 $0 -- $75,644 $0 -- $241,869 $0
HARROW, INC. -- $0 $0 -- $468,720 $0 -- $468,720 $0
Whitehawk Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,459,560) 0.00 $0 ($2,459,560)
Rani Therapeutics Holdings, Inc. -- $0 $0 166.18 $50,033 ($301) 4352.50 $1,310,450 ($301)
Pepgen Inc. -- $0 $0 0.00 $0 ($1,739) 505.80 $30,000,000 ($59,312)
ASTRAZENECA PLC -- $0 $0 0.00 $3,211 ($2,209,482) 0.00 $3,211 ($2,209,482)
Legend Biotech Corp -- $0 $0 0.00 $0 ($258,204) 0.00 $0 ($258,204)
AC Immune SA -- $0 $0 0.00 $0 ($59,360) 0.00 $0 ($59,360)
Pharvaris N.V. -- $0 $0 0.00 $0 ($4,807,907) 0.00 $0 ($4,807,907)
Tiziana Life Sciences Ltd -- $0 $0 -- $1,044,492 $0 -- $1,044,492 $0
ProQR Therapeutics N.V. -- $0 $0 -- $1,342,385 $0 -- $1,342,385 $0
Adagene Inc. -- $0 $0 -- $92,264 $0 -- $92,264 $0
Connect Biopharma Holdings Ltd -- $0 $0 -- $4,373,610 $0 -- $4,373,610 $0
RedHill Biopharma Ltd. -- $0 $0 0.00 $0 ($2,987) 0.00 $0 ($2,987)
Serina Therapeutics, Inc. -- $0 $0 -- $76,881 $0 -- $76,881 $0
NeuroSense Therapeutics Ltd. -- $0 $0 -- $400,000 $0 -- $400,000 $0
Valion Bio, Inc. -- $0 $0 -- $28,408 $0 -- $28,408 $0
NewcelX Ltd. -- $0 $0 -- $374,998 $0 -- $374,998 $0
SciSparc Ltd. -- $0 $0 0.00 $0 ($4,620) 0.00 $0 ($4,620)
Cadrenal Therapeutics, Inc. -- $0 $0 0.00 $0 ($388,290) 0.00 $0 ($999,753)
Mineralys Therapeutics, Inc. -- $0 $0 1.89 $8,762,797 ($4,644,544) 0.15 $8,762,797 ($59,909,964)
CytoMed Therapeutics Ltd -- $0 $0 -- $428,778 $0 -- $428,778 $0
Apollomics Inc. -- $0 $0 -- $8,250,009 $0 -- $8,250,009 $0
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $10,131 $0 -- $30,095 $0
Sagimet Biosciences Inc. -- $0 $0 0.00 $0 ($719,429) 0.00 $0 ($1,114,872)
Contineum Therapeutics, Inc. -- $0 $0 0.00 $0 ($165,570) 0.00 $0 ($385,013)
IMPACT BIOMEDICAL INC. -- $0 $0 0.00 $0 ($57,835) 0.00 $0 ($57,835)
Zenas Biopharma, Inc. -- $0 $0 -- $7,671,338 $0 -- $26,646,644 $0
Mbx Biosciences, Inc. -- $0 $0 0.00 $0 ($49,089) 266.11 $13,063,425 ($49,089)
Upstream Bio, Inc. -- $0 $0 0.00 $0 ($77,193) 0.00 $0 ($77,193)
Septerna, Inc. -- $0 $0 0.00 $0 ($63,452,500) 0.00 $0 ($63,515,723)
Sionna Therapeutics, Inc. -- $0 $0 0.00 $0 ($95,822,256) 0.00 $0 ($154,898,570)
Nasus Pharma Ltd -- $0 $0 -- $61,809 $0 -- $61,809 $0
MapLight Therapeutics, Inc. -- $0 $0 0.01 $148,702 ($27,615,051) 0.03 $842,548 ($28,983,128)
Evommune, Inc. -- $0 $0 0.22 $146,260 ($673,747) 0.24 $163,610 ($673,747)
Veradermics, Inc -- $0 $0 0.00 $0 ($10,711,700) 1.45 $15,542,467 ($10,711,700)
Polaryx Therapeutics, Inc. -- $0 $0 -- $360,004 $0 -- $367,994 $0
Seaport Therapeutics, Inc. -- $0 $0 -- $235,768 $0 -- $235,768 $0
Parabilis Medicines, Inc. -- $0 $0 -- $7,643,080 $0 -- $7,643,080 $0
Kardigan, Inc. -- $0 $0 -- $40,000,000 $0 -- $40,000,000 $0
Apnimed, Inc. -- $0 $0 -- $200,000 $0 -- $200,000 $0
Braveheart Bio, Inc. -- $0 $0 -- $4,594,950 $0 -- $4,594,950 $0
Blossomhill Therapeutics, Inc. -- $0 $0 -- $107,200 $0 -- $107,200 $0
Amicus Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,471,085)
Apellis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,191,131)
KALA BIO, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($248,725)
Zentalis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($134,670)
Harmony Biosciences Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,011,950)
Cartesian Therapeutics, Inc. -- $0 $0 -- $0 $0 0.80 $205,797 ($258,671)
Rallybio Corp -- $0 $0 -- $0 $0 0.00 $0 ($3,992)
Galectin Therapeutics Inc -- $0 $0 -- $0 $0 -- $25,546 $0
Enanta Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($183,167)
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $196,731 $0
Bolt Biotherapeutics, Inc. -- $0 $0 -- $0 $0 -- $1,152 $0
Clene Inc. -- $0 $0 -- $0 $0 -- $216,664 $0
Abbvie Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,597,068)
Phathom Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($7,079)
Aprea Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $60,907 $0
Vanda Pharmaceuticals Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,824,768)
Perrigo Co Plc -- $0 $0 -- $0 $0 -- $106,350 $0
Decoy Therapeutics Inc. -- $0 $0 -- $0 $0 1142.93 $19,740 ($17)
Edesa Biotech, Inc. -- $0 $0 -- $0 $0 -- $233,054 $0
Organogenesis Holdings Inc. -- $0 $0 -- $0 $0 0.02 $40,093 ($2,619,180)
Iterum Therapeutics Plc -- $0 $0 -- $0 $0 -- $2,191 $0
Cingulate Inc. -- $0 $0 -- $0 $0 -- $656,964 $0
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,816)
XOMA Royalty Corp -- $0 $0 -- $0 $0 -- $2,505,000 $0
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($198)
Synlogic, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($284)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,806)
Cue Biopharma, Inc. -- $0 $0 -- $0 $0 -- $99,747 $0
Ideaya Biosciences, Inc. -- $0 $0 -- $0 $0 -- $1,647,890 $0
Monopar Therapeutics -- $0 $0 -- $0 $0 0.31 $104,925 ($343,889)
Galera Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,407)
Savara Inc -- $0 $0 -- $0 $0 0.00 $0 ($121,220)
Sarepta Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($417,410)
Mustang Bio, Inc. -- $0 $0 -- $0 $0 0.98 $238 ($241)
Lexicon Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $2,722,625 $0
Avidity Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,226,448)
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($163,620)
Supernus Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($3,304,084)
Cogent Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($139,578,705)
Therapeuticsmd, Inc. -- $0 $0 -- $0 $0 -- $14,031 $0
Silo Pharma, Inc. -- $0 $0 -- $0 $0 -- $7,657 $0
Soligenix, Inc. -- $0 $0 -- $0 $0 -- $20,000 $0
Cormedix Inc. -- $0 $0 -- $0 $0 0.31 $275,500 ($886,600)
Aditxt, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5)
Centessa Pharmaceuticals Plc -- $0 $0 -- $0 $0 0.00 $0 ($3,395,184)
Palatin Technologies Inc -- $0 $0 -- $0 $0 0.00 $0 ($9,461)
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($29,286)
Climb Bio, Inc. -- $0 $0 -- $0 $0 0.89 $779,626 ($879,382)
Catalyst Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -0.00 $0 $908,000
Sellas Life Sciences Group, Inc. -- $0 $0 -- $0 $0 -- $100,806 $0
Immix Biopharma, Inc. -- $0 $0 -- $0 $0 -- $15,148 $0
Rockwell Medical, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($23,677)
Tenax Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $204,468 $0
TALPHERA, INC. -- $0 $0 -- $0 $0 -- $304,001 $0
Tango Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,725,098)
FILANA THERAPEUTICS, INC. -- $0 $0 -- $0 $0 -- $1,231,784 $0
Geovax Labs, Inc. -- $0 $0 -- $0 $0 -- $5,498 $0
Perspective Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $42,241 $0
Aptevo Therapeutics Inc. -- $0 $0 -- $0 $0 -- $20,134 $0
Benitec Biopharma Inc. -- $0 $0 -- $0 $0 -- $22,442,099 $0
Pasithea Therapeutics Corp. -- $0 $0 -- $0 $0 -- $149,999 $0
Biohaven Ltd. -- $0 $0 -- $0 $0 -- $33,144,763 $0
Carisma Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($124,343)
ONCOLYTICS BIOTECH INC -- $0 $0 -- $0 $0 -- $362,615 $0
BIOXYTRAN, INC -- $0 $0 -- $0 $0 -- $126,000 $0
Mural Oncology plc -- $0 $0 -- $0 $0 0.00 $0 ($25,414)
FibroBiologics, Inc. -- $0 $0 -- $0 $0 -- $120,560 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,624,000)
Bicara Therapeutics Inc. -- $0 $0 -- $0 $0 66.68 $4,800,000 ($71,981)
Bioage Labs, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,223,036)
Turn Therapeutics Inc. -- $0 $0 -- $0 $0 -- $242,745 $0
Ataibeckley Inc. -- $0 $0 -- $0 $0 0.00 $0 ($154,377)