Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 10/29/2025 10:06:27 PM
1 Month
Buy/Sell Ratio 0.37
27%
73%
Buy Sell
$38.87 M ($104.44) M
25 Insiders 93 Insiders
28 Transactions 162 Transactions
9/29/2025 to 10/29/2025
3 Month
Buy/Sell Ratio 1.90
65%
35%
Buy Sell
$610.50 M ($320.79) M
109 Insiders 271 Insiders
252 Transactions 541 Transactions
7/29/2025 to 10/29/2025
6 Month
Buy/Sell Ratio 1.68
62%
38%
Buy Sell
$751.61 M ($448.11) M
242 Insiders 425 Insiders
763 Transactions 1023 Transactions
4/29/2025 to 10/29/2025
12 Month
Buy/Sell Ratio 0.81
44%
56%
Buy Sell
$1,100.09 M ($1,358.09) M
437 Insiders 785 Insiders
1603 Transactions 2330 Transactions
10/29/2024 to 10/29/2025

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Bausch Health Companies Inc.
$369,628,560 8
Madrigal Pharmaceuticals, Inc.
$61,921,024 3
Zymeworks Inc.
$58,036,053 36
89Bio, Inc.
$49,999,994 1
Mineralys Therapeutics, Inc.
$47,499,981 2
Aurinia Pharmaceuticals Inc.
$37,125,126 9
Tyra Biosciences, Inc.
$35,156,072 7
Larimar Therapeutics, Inc.
$30,000,000 3
Pepgen Inc.
$30,000,000 1
Janux Therapeutics, Inc.
$25,342,965 3

Most Insider Selling

12 months
Name Value Transactions
BeOne Medicines Ltd.
($384,735,063) 2
Nuvalent, Inc.
($110,000,000) 1
Bridgebio Pharma, Inc.
($47,157,019) 23
Sionna Therapeutics, Inc.
($22,085,832) 26
Abbvie Inc.
($20,263,020) 2
Disc Medicine, Inc.
($20,108,066) 7
Disc Medicine, Inc.
($20,108,066) 7
Disc Medicine, Inc.
($19,663,022) 13
BeOne Medicines Ltd.
($19,580,110) 6
Liquidia Corp
($18,957,475) 3

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Eli Lilly & Co 8 8
Zenas Biopharma, Inc. 6 12
Mbx Biosciences, Inc. 6 9
Perspective Therapeutics, Inc. 6 9
Hcw Biologics Inc. 6 8
Avadel Pharmaceuticals Plc 6 7
Organon & Co. 6 6
Perrigo Co Plc 5 7
CalciMedica, Inc. 5 7
Zomedica Corp. 5 7

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Ani Pharmaceuticals Inc 14 32
Apellis Pharmaceuticals, Inc. 12 41
Ionis Pharmaceuticals Inc 12 31
Blueprint Medicines Corp 11 26
Liquidia Corp 10 24
Uniqure N.V. 10 16
Puma Biotechnology, Inc. 10 13
Insmed Inc 9 63
Disc Medicine, Inc. 9 38
Ptc Therapeutics, Inc. 9 36

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Sionna Therapeutics, Inc. 0.00 $0 ($34,859,336) 0.00 $0 ($38,815,070) 0.00 $0 ($38,815,070)
Disc Medicine, Inc. 0.00 $0 ($14,357,752) 0.00 $0 ($20,591,665) 0.00 $0 ($61,695,050)
Alnylam Pharmaceuticals, Inc. 0.00 $0 ($10,192,008) 0.00 $0 ($18,508,993) 0.00 $0 ($26,888,997)
Precigen, Inc. 0.00 $0 ($6,532,074) 0.03 $235,938 ($6,775,156) 0.03 $235,938 ($6,775,156)
Nuvalent, Inc. 0.00 $0 ($6,015,464) 0.00 $0 ($6,015,464) 0.00 $0 ($119,470,579)
Bridgebio Pharma, Inc. 0.00 $0 ($4,490,107) 0.00 $0 ($42,459,492) 0.00 $0 ($72,796,044)
Viking Therapeutics, Inc. 0.00 $0 ($3,932,173) 0.00 $0 ($4,916,707) 0.00 $29,943 ($17,698,502)
Corcept Therapeutics Inc 0.00 $0 ($3,403,253) 0.00 $0 ($17,220,994) 0.00 $0 ($21,110,844)
Ionis Pharmaceuticals Inc 0.00 $0 ($2,074,818) 0.05 $477,900 ($8,887,583) 0.06 $658,979 ($11,869,880)
Phibro Animal Health Corp 0.00 $0 ($1,600,353) 0.00 $0 ($2,457,667) 0.04 $110,500 ($2,457,667)
Apellis Pharmaceuticals, Inc. 0.00 $0 ($1,565,694) 0.00 $0 ($9,627,656) 0.00 $0 ($12,712,612)
Mineralys Therapeutics, Inc. 0.00 $0 ($1,542,293) 12.54 $44,999,978 ($3,588,694) 17.77 $74,099,970 ($4,169,127)
Oric Pharmaceuticals, Inc. 0.00 $0 ($1,515,074) 0.08 $262,899 ($3,482,406) 0.08 $262,899 ($3,482,406)
Cytokinetics Inc 0.00 $0 ($1,349,581) 0.00 $0 ($4,081,442) 0.00 $0 ($11,250,053)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($1,319,258) 0.00 $0 ($1,565,407) 0.02 $37,005 ($2,059,877)
Supernus Pharmaceuticals, Inc. 0.00 $0 ($1,269,234) 0.00 $0 ($2,605,335) 0.00 $0 ($2,921,769)
Stoke Therapeutics, Inc. 0.00 $0 ($1,191,522) 0.00 $0 ($3,514,630) 0.00 $0 ($4,463,914)
Arcutis Biotherapeutics, Inc. 0.00 $0 ($974,912) 0.12 $373,039 ($3,032,904) 0.07 $407,062 ($5,649,129)
Jazz Pharmaceuticals Plc 0.00 $0 ($753,560) 4.92 $9,993,082 ($2,031,390) 1.57 $9,993,082 ($6,361,051)
Arrowhead Pharmaceuticals, Inc. 0.00 $0 ($700,000) 0.00 $0 ($1,725,000) 0.00 $0 ($7,904,759)
Enliven Therapeutics, Inc. 0.00 $0 ($676,671) 0.00 $0 ($4,184,874) 0.00 $0 ($5,274,642)
Rapport Therapeutics, Inc. 0.00 $0 ($500,925) 0.51 $1,605,585 ($3,138,983) 0.53 $1,767,823 ($3,312,499)
ELITE PHARMACEUTICALS INC /NV/ 0.00 $0 ($499,200) 0.02 $9,640 ($615,000) 0.02 $9,640 ($615,000)
Ocular Therapeutix, Inc 0.00 $0 ($359,784) 0.07 $69,600 ($1,047,968) 0.04 $69,600 ($1,641,719)
Emergent Biosolutions Inc. 0.00 $0 ($306,080) 0.72 $349,800 ($486,181) 0.29 $349,800 ($1,191,296)
Werewolf Therapeutics, Inc. 0.00 $0 ($286,497) 1.70 $487,188 ($286,497) 1.70 $487,188 ($286,497)
Vertex Pharmaceuticals Inc / Ma 0.00 $0 ($280,522) 9.62 $5,844,183 ($607,809) 0.20 $5,844,183 ($28,919,620)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($250,252) 0.00 $0 ($441,450) 0.00 $0 ($8,168,346)
KALA BIO, Inc. 0.00 $0 ($248,725) 0.00 $0 ($452,240) 0.00 $0 ($524,771)
Cadrenal Therapeutics, Inc. 0.00 $0 ($229,006) 0.00 $0 ($640,578) 0.00 $0 ($640,578)
Aquestive Therapeutics, Inc. 0.00 $0 ($211,904) 0.00 $0 ($907,995) 0.00 $0 ($908,209)
Abeona Therapeutics Inc. 0.00 $0 ($132,296) 0.00 $0 ($1,987,806) 0.00 $0 ($2,149,226)
Carisma Therapeutics Inc. 0.00 $0 ($124,343) 0.00 $0 ($124,343) 0.00 $0 ($124,343)
Rocket Pharmaceuticals, Inc. 0.00 $0 ($114,581) 0.11 $34,100 ($310,306) 0.22 $234,865 ($1,076,195)
Liquidia Corp 0.00 $0 ($109,039) 0.00 $0 ($21,240,140) 0.00 $0 ($22,703,635)
Arcus Biosciences, Inc. 0.00 $0 ($100,000) 0.00 $0 ($155,561) 1.89 $402,665 ($212,550)
Bicycle Therapeutics Plc 0.00 $0 ($92,962) 0.00 $0 ($170,024) 26.44 $21,230,385 ($802,917)
Ligand Pharmaceuticals Inc 0.00 $0 ($83,800) 0.51 $1,156,546 ($2,264,312) 0.37 $1,156,546 ($3,084,311)
Verastem, Inc. 0.00 $0 ($75,497) 0.00 $0 ($789,585) 0.00 $0 ($859,275)
Ani Pharmaceuticals Inc 0.00 $0 ($36,036) 0.00 $0 ($32,625,839) 0.00 $0 ($33,849,364)
Schrodinger, Inc. 0.00 $0 ($29,387) 0.00 $0 ($29,387) 0.00 $0 ($260,045)
Rockwell Medical, Inc. 0.00 $0 ($16,122) 0.00 $0 ($24,880) 0.00 $0 ($113,308)
Amphastar Pharmaceuticals, Inc. 0.00 $0 ($13,602) 0.00 $0 ($76,120) 0.00 $0 ($118,297)
Alzamend Neuro, Inc. 0.00 $0 ($8,390) 0.00 $0 ($318,590) 0.07 $21,072 ($318,590)
Terns Pharmaceuticals, Inc. 0.00 $0 ($7,407) 16.89 $186,595 ($11,047) 1.39 $311,166 ($224,504)
Esperion Therapeutics, Inc. 0.00 $0 ($3,275) 0.00 $0 ($170,891) 0.00 $0 ($244,666)
Karyopharm Therapeutics Inc. 0.00 $0 ($2,279) 0.00 $0 ($22,854) 0.00 $0 ($203,463)
Zenas Biopharma, Inc. -- $15,228,178 $0 -- $15,228,178 $0 -- $16,339,553 $0
Summit Therapeutics Inc. -- $10,999,949 $0 -- $22,969,461 $0 -- $22,969,461 $0
Viridian Therapeutics, Inc.\De -- $9,999,990 $0 -- $9,999,990 $0 -- $9,999,990 $0
Rani Therapeutics Holdings, Inc. -- $1,260,417 $0 -- $1,260,417 $0 -- $1,310,385 $0
Mbx Biosciences, Inc. -- $537,774 $0 -- $12,537,762 $0 -- $17,159,085 $0
Cormedix Inc. -- $275,500 $0 -- $275,500 $0 -- $290,485 $0
Quoin Pharmaceuticals, Ltd. -- $128,640 $0 -- $128,640 $0 -- $728,640 $0
Turn Therapeutics Inc. -- $124,997 $0 -- $124,997 $0 -- $124,997 $0
Immuneering Corp -- $116,742 $0 -- $486,700 $0 -- $486,700 $0
MoonLake Immunotherapeutics -- $98,808 $0 -- $98,808 $0 -- $98,808 $0
Cassava Sciences Inc -- $39,940 $0 -- $591,035 $0 38.18 $591,035 ($15,480)
Maia Biotechnology, Inc. -- $24,999 $0 -- $204,998 $0 -- $1,208,623 $0
Soligenix, Inc. -- $20,000 $0 -- $20,000 $0 -- $20,000 $0
Annexon, Inc. -- $12,551 $0 5.17 $41,273 ($7,987) 0.43 $58,329 ($134,425)
Geovax Labs, Inc. -- $5,498 $0 -- $6,240 $0 -- $40,123 $0
Eli Lilly & Co -- $0 $0 1.43 $4,537,301 ($3,171,652) 0.50 $4,537,301 ($9,028,999)
Arvinas, Inc. -- $0 $0 3.62 $227,010 ($62,724) 0.25 $227,010 ($908,698)
Aurinia Pharmaceuticals Inc. -- $0 $0 64.71 $13,590,000 ($210,000) 6.03 $37,125,126 ($6,156,646)
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($129,840) 0.00 $0 ($300,311)
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($630,447) 0.00 $0 ($826,288)
Akebia Therapeutics, Inc. -- $0 $0 0.00 $0 ($198,691) 0.00 $0 ($885,909)
Zentalis Pharmaceuticals, Inc. -- $0 $0 -- $29,373 $0 3.86 $252,786 ($65,472)
Harmony Biosciences Holdings, Inc. -- $0 $0 0.00 $0 ($787,378) 0.00 $0 ($1,014,764)
Kezar Life Sciences, Inc. -- $0 $0 0.00 $0 ($3,531) 0.00 $0 ($3,531)
Arcturus Therapeutics Holdings Inc. -- $0 $0 -- $20,499 $0 -- $20,499 $0
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($369,437) 0.00 $0 ($2,094,808)
Travere Therapeutics, Inc. -- $0 $0 0.00 $0 ($30,684) 0.00 $0 ($2,480,453)
Ptc Therapeutics, Inc. -- $0 $0 0.00 $0 ($763,677) 0.00 $0 ($4,292,868)
United Therapeutics Corp -- $0 $0 0.00 $0 ($1,215,016) 0.00 $0 ($2,312,007)
Insmed Inc -- $0 $0 0.01 $201,694 ($17,621,706) 0.00 $201,694 ($49,933,407)
Anixa Biosciences Inc -- $0 $0 -- $139,200 $0 -- $325,241 $0
Urogen Pharma Ltd. -- $0 $0 0.00 $0 ($176,900) 0.00 $0 ($176,900)
Cumberland Pharmaceuticals Inc -- $0 $0 -- $29,231 $0 -- $68,215 $0
Tg Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,041,668) 0.00 $0 ($3,067,726)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($1,132,946) 0.00 $0 ($1,222,619)
Akero Therapeutics, Inc. -- $0 $0 0.00 $0 ($7,885,721) 1.05 $18,387,921 ($17,543,543)
Olema Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($204,841) 0.00 $0 ($2,141,237)
Q32 Bio Inc. -- $0 $0 0.00 $0 ($31,921) 0.00 $0 ($31,921)
Hookipa Pharma Inc. -- $0 $0 0.00 $0 ($60,046) 0.00 $0 ($60,046)
Galectin Therapeutics Inc -- $0 $0 -- $17,420 $0 -- $52,303 $0
Entrada Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,069,186) 0.00 $0 ($1,830,422)
Biomarin Pharmaceutical Inc -- $0 $0 0.00 $0 ($123,651) 0.00 $0 ($1,159,851)
Tharimmune, Inc. -- $0 $0 -- $593,424 $0 -- $613,272 $0
Shattuck Labs, Inc. -- $0 $0 -- $10,943,653 $0 -- $10,943,653 $0
Bausch Health Companies Inc. -- $0 $0 1683.03 $369,628,560 ($219,621) 1655.34 $369,628,560 ($223,295)
Pacira Biosciences, Inc. -- $0 $0 0.00 $0 ($703,698) 0.00 $0 ($729,752)
Xenon Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($91) 0.00 $0 ($91)
Zai Lab Ltd -- $0 $0 0.17 $289,100 ($1,740,677) 0.10 $289,100 ($2,917,943)
Soleno Therapeutics Inc -- $0 $0 0.00 $0 ($316,971) 0.00 $0 ($2,269,296)
Regulus Therapeutics Inc. -- $0 $0 -- $95,852 $0 0.55 $170,899 ($310,669)
Uniqure N.V. -- $0 $0 0.00 $0 ($322,426) 0.00 $0 ($1,396,278)
89Bio, Inc. -- $0 $0 0.00 $0 ($115,280) 99.68 $50,302,794 ($504,632)
Bolt Biotherapeutics, Inc. -- $0 $0 -- $1,373 $0 -- $3,856 $0
Mannkind Corp -- $0 $0 0.00 $0 ($1,423,640) 0.00 $0 ($1,827,340)
Verona Pharma Plc -- $0 $0 0.00 $0 ($17,603,746) 0.02 $476,066 ($30,641,386)
Syndax Pharmaceuticals Inc -- $0 $0 2.95 $241,896 ($81,987) 0.58 $241,896 ($418,160)
Abbvie Inc. -- $0 $0 0.00 $0 ($2,639,219) 0.00 $0 ($32,264,257)
Lifevantage Corp -- $0 $0 0.42 $20,768 ($49,460) 0.06 $24,400 ($414,080)
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $20,988 ($7,049,769) 0.00 $20,988 ($16,230,364)
Vera Therapeutics, Inc. -- $0 $0 -- $5,277,311 $0 9.65 $5,277,311 ($546,914)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($315,091) 0.00 $0 ($1,494,167)
GYRE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($204,429) 0.00 $0 ($1,546,917)
Zoetis Inc. -- $0 $0 0.00 $0 ($110,840) 0.00 $0 ($367,289)
Wave Life Sciences Ltd. -- $0 $0 0.00 $0 ($2,640,994) 0.00 $0 ($3,374,665)
Phathom Pharmaceuticals, Inc. -- $0 $0 11.00 $216,973 ($19,725) 1.59 $441,505 ($276,949)
Nektar Therapeutics -- $0 $0 0.00 $0 ($968,206) 0.00 $0 ($1,269,044)
Abbott Laboratories -- $0 $0 0.00 $0 ($1,083,874) 0.00 $0 ($1,969,919)
Alkermes Plc. -- $0 $0 0.00 $0 ($210,143) 0.00 $0 ($1,403,137)
Xeris Biopharma Holdings, Inc. -- $0 $0 0.09 $109,475 ($1,215,295) 0.08 $109,475 ($1,432,539)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,428,100) 0.00 $0 ($8,315,773)
Ardelyx, Inc. -- $0 $0 4.01 $3,403,196 ($848,166) 4.48 $6,777,784 ($1,511,980)
Bristol Myers Squibb Co -- $0 $0 0.00 $0 ($2,654,167) 0.19 $512,340 ($2,693,097)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($1,072,217) 0.00 $0 ($3,531,882)
Vanda Pharmaceuticals Inc. -- $0 $0 5.29 $169,967 ($32,130) 8.86 $513,636 ($57,993)
Theravance Biopharma, Inc. -- $0 $0 0.00 $0 ($377,870) 0.00 $0 ($485,870)
Ironwood Pharmaceuticals Inc -- $0 $0 0.00 $0 ($20,303) 0.00 $0 ($515,389)
Dyne Therapeutics, Inc. -- $0 $0 5.00 $911,000 ($182,105) 0.07 $911,000 ($12,686,521)
Dynavax Technologies Corp -- $0 $0 -- $41,116 $0 0.06 $41,116 ($661,866)
Blueprint Medicines Corp -- $0 $0 0.00 $0 ($1,085,076) 0.00 $0 ($9,249,126)
Xencor Inc -- $0 $0 0.00 $0 ($183,378) 0.00 $0 ($726,467)
Perrigo Co Plc -- $0 $0 -- $551,000 $0 1.11 $551,000 ($497,495)
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 0.00 $0 ($30,561) 0.00 $0 ($160,802)
Roivant Sciences Ltd. -- $0 $0 -- $49,957 $0 -- $49,957 $0
Evolus, Inc. -- $0 $0 0.25 $393,486 ($1,580,390) 0.10 $393,486 ($3,900,468)
Kalvista Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($992,221) 0.00 $0 ($992,221)
Cryoport, Inc. -- $0 $0 0.00 $0 ($234,271) 0.00 $0 ($347,789)
Organogenesis Holdings Inc. -- $0 $0 -- $725,290 $0 0.57 $725,290 ($1,273,959)
Spyre Therapeutics, Inc. -- $0 $0 0.00 $0 ($299,639) 0.00 $0 ($545,952)
Viatris Inc -- $0 $0 10.49 $756,002 ($72,045) 1.81 $756,002 ($418,731)
Iterum Therapeutics Plc -- $0 $0 -- $10,854 $0 -- $10,854 $0
Gossamer Bio, Inc. -- $0 $0 -- $50,016 $0 -- $50,016 $0
Johnson & Johnson -- $0 $0 0.00 $0 ($3,129,830) 0.05 $147,220 ($3,129,830)
XOMA Royalty Corp -- $0 $0 -- $50,780 $0 -- $760,508 $0
Tonix Pharmaceuticals Holding Corp. -- $0 $0 -- $110,261 $0 -- $110,261 $0
Igm Biosciences, Inc. -- $0 $0 0.00 $0 ($42,658) 0.00 $0 ($107,771)
CalciMedica, Inc. -- $0 $0 66.49 $242,702 ($3,650) 309.91 $1,131,171 ($3,650)
Relmada Therapeutics, Inc. -- $0 $0 -- $639,406 $0 -- $639,406 $0
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,520) 0.00 $0 ($2,520)
Nuvation Bio Inc. -- $0 $0 -- $1,103,906 $0 12.84 $2,091,111 ($162,883)
Longeveron Inc. -- $0 $0 0.00 $0 ($36,757) 0.00 $0 ($39,345)
Bespoke Extracts, Inc. -- $0 $0 -- $2,850 $0 -- $6,095 $0
Heron Therapeutics, Inc. /De/ -- $0 $0 -- $2,649,819 $0 -- $2,649,819 $0
Fibrogen Inc -- $0 $0 -- $119,485 $0 -- $275,188 $0
BeOne Medicines Ltd. -- $0 $0 0.00 $0 ($26,831,329) 0.00 $0 ($415,567,937)
Protagonist Therapeutics, Inc -- $0 $0 0.00 $0 ($3,944,577) 0.00 $0 ($4,525,068)
Nkarta, Inc. -- $0 $0 0.00 $0 ($3,204) 0.00 $0 ($110,751)
Kiniksa Pharmaceuticals International, plc -- $0 $0 0.00 $0 ($124,397) 0.00 $0 ($494,872)
Zomedica Corp. -- $0 $0 -- $114,713 $0 -- $497,039 $0
Neurogene Inc. -- $0 $0 0.00 $0 ($103,003) 8.15 $1,460,400 ($179,250)
Anaptysbio, Inc -- $0 $0 0.00 $0 ($144,539) 7.61 $1,099,642 ($144,539)
Savara Inc -- $0 $0 -- $119,397 $0 3.04 $882,319 ($290,675)
Phio Pharmaceuticals Corp. -- $0 $0 -- $27,011 $0 -- $27,011 $0
Immunic, Inc. -- $0 $0 -- $246,928 $0 -- $347,297 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $124,750 $0 -- $133,150 $0
Mirum Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($155,091) 0.15 $280,117 ($1,911,152)
Macrogenics Inc -- $0 $0 -- $150,515 $0 -- $150,515 $0
Alx Oncology Holdings Inc -- $0 $0 45.32 $157,755 ($3,481) 6.50 $204,159 ($31,433)
Amneal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($9,779,394) 0.00 $0 ($16,778,550)
Kura Oncology, Inc. -- $0 $0 0.99 $713,346 ($717,079) 0.79 $713,346 ($904,670)
Avidity Biosciences, Inc. -- $0 $0 0.00 $0 ($1,438,599) 0.00 $0 ($6,836,835)
Design Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,953,792) 0.00 $0 ($2,977,655)
Pmv Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($152,104) 0.00 $0 ($152,104)
Eton Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($4,770,642) 0.00 $0 ($4,770,642)
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,958) 0.00 $0 ($13,706)
Cogent Biosciences, Inc. -- $0 $0 -- $24,999,993 $0 -- $25,332,406 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 1.03 $228,343 ($221,004) 0.27 $310,319 ($1,140,979)
CervoMed Inc. -- $0 $0 -- $35,811 $0 -- $35,811 $0
Silo Pharma, Inc. -- $0 $0 -- $4,329 $0 -- $11,051 $0
Immunome Inc. -- $0 $0 -- $46,900 $0 -- $3,740,590 $0
Opko Health, Inc. -- $0 $0 -- $891,000 $0 -- $5,187,381 $0
Kronos Bio, Inc. -- $0 $0 0.00 $0 ($21,554) 0.00 $0 ($21,554)
Centessa Pharmaceuticals Plc -- $0 $0 19.45 $5,865,242 ($301,597) 1.08 $5,865,242 ($5,426,895)
Larimar Therapeutics, Inc. -- $0 $0 -- $30,000,000 $0 -- $30,000,000 $0
Palatin Technologies Inc -- $0 $0 -- $10,180 $0 -- $10,180 $0
Jade Biosciences, Inc. -- $0 $0 -- $44,400 $0 -- $44,400 $0
Atossa Therapeutics, Inc. -- $0 $0 -- $9,887 $0 -- $16,887 $0
Hcw Biologics Inc. -- $0 $0 -- $3,045,056 $0 -- $3,045,056 $0
Rezolute, Inc. -- $0 $0 -- $4,041,185 $0 -- $4,284,918 $0
Catalyst Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,580,787) 0.00 $0 ($4,277,170)
Organon & Co. -- $0 $0 -- $651,626 $0 -- $651,626 $0
Tyra Biosciences, Inc. -- $0 $0 24.38 $15,320,006 ($628,263) 7.63 $35,308,026 ($4,627,246)
Context Therapeutics Inc. -- $0 $0 -- $107,086 $0 -- $107,086 $0
Xilio Therapeutics, Inc. -- $0 $0 -- $72,765 $0 -- $72,765 $0
Io Biotech, Inc. -- $0 $0 -- $20,884 $0 -- $75,761 $0
Axsome Therapeutics, Inc. -- $0 $0 0.01 $200,466 ($14,479,691) 0.01 $200,466 ($14,479,691)
Sellas Life Sciences Group, Inc. -- $0 $0 -- $84,600 $0 -- $84,600 $0
Immix Biopharma, Inc. -- $0 $0 -- $20,241 $0 -- $124,599 $0
Ainos, Inc. -- $0 $0 0.00 $0 ($23,639) 0.00 $0 ($23,639)
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($16,286) 0.00 $0 ($304,681)
Geron Corp -- $0 $0 -- $15,667 $0 -- $221,880 $0
Madrigal Pharmaceuticals, Inc. -- $0 $0 9.14 $61,921,024 ($6,771,124) 4.86 $61,921,024 ($12,748,745)
AYTU BIOPHARMA, INC -- $0 $0 -- $124,998 $0 -- $144,498 $0
Aldeyra Therapeutics, Inc. -- $0 $0 0.12 $13,250 ($113,713) 0.12 $13,250 ($113,713)
Oncotelic Therapeutics, Inc. -- $0 $0 -- $994 $0 -- $19,332 $0
Natures Sunshine Products Inc -- $0 $0 0.00 $0 ($409,803) 0.00 $0 ($409,803)
Skye Bioscience, Inc. -- $0 $0 0.00 $0 ($800,548) 0.00 $0 ($1,960,011)
Earth Science Tech, Inc. -- $0 $0 -- $48,349 $0 -- $353,711 $0
Renovorx, Inc. -- $0 $0 -- $38,696 $0 -- $158,086 $0
An2 Therapeutics, Inc. -- $0 $0 -- $20,798 $0 21.35 $504,135 ($23,610)
Lexaria Bioscience Corp. -- $0 $0 -- $49,085 $0 -- $167,477 $0
Lyell Immunopharma, Inc. -- $0 $0 0.00 $0 ($133,557) 3.35 $447,931 ($133,557)
Rafael Holdings, Inc. -- $0 $0 -- $16,742,985 $0 -- $16,742,985 $0
Accustem Sciences Inc. -- $0 $0 -- $20,902 $0 -- $162,579 $0
Pepgen Inc. -- $0 $0 -- $30,010,393 $0 6049.27 $30,071,668 ($4,971)
Pasithea Therapeutics Corp. -- $0 $0 0.00 $0 ($792) 0.00 $0 ($792)
Journey Medical Corp -- $0 $0 0.00 $0 ($69,084) 0.00 $0 ($887,229)
Zymeworks Inc. -- $0 $0 -- $635,586 $0 -- $58,036,053 $0
Aspire Biopharma Holdings, Inc. -- $0 $0 1.00 $7,800 ($7,800) 1.00 $7,800 ($7,800)
AEON Biopharma, Inc. -- $0 $0 -- $84,550 $0 -- $84,550 $0
Akari Therapeutics Plc -- $0 $0 -- $56,660 $0 -- $56,660 $0
MetaVia Inc. -- $0 $0 -- $9,940 $0 -- $9,940 $0
NewAmsterdam Pharma Co N.V. -- $0 $0 0.09 $295,267 ($3,130,659) 0.13 $404,991 ($3,130,659)
GENELUX CORP -- $0 $0 0.00 $0 ($78,297) 0.00 $0 ($145,842)
JUPITER NEUROSCIENCES, INC. -- $0 $0 -- $4,439 $0 -- $4,439 $0
BullFrog AI Holdings, Inc. -- $0 $0 0.00 $0 ($76,536) 0.00 $0 ($150,630)
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $14,410 $0 -- $131,933 $0
Sagimet Biosciences Inc. -- $0 $0 0.00 $0 ($772,193) 0.00 $0 ($772,193)
Mural Oncology plc -- $0 $0 0.00 $0 ($42,206) 0.00 $0 ($177,234)
FibroBiologics, Inc. -- $0 $0 -- $16,800 $0 -- $16,800 $0
NEONC TECHNOLOGIES HOLDINGS, INC. -- $0 $0 -- $206,740 $0 -- $207,889 $0
ALUMIS INC. -- $0 $0 -- $1,679,612 $0 -- $1,909,889 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $1,499,988 $0 -- $1,499,988 $0
Camp4 Therapeutics Corp -- $0 $0 -- $2,054,995 $0 -- $2,054,995 $0
Apimeds Pharmaceuticals US, Inc. -- $0 $0 -- $107,074 $0 -- $107,074 $0
Aardvark Therapeutics, Inc. -- $0 $0 -- $305,717 $0 -- $305,717 $0
Greenwich Lifesciences, Inc. -- $0 $0 -- $0 $0 -- $379,229 $0
Processa Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $9,889 $0
Avid Bioservices, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,785,375)
Day One Biopharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,043,859)
Y-Mabs Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($76,905)
Syros Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($122,320)
Cartesian Therapeutics, Inc. -- $0 $0 -- $0 $0 19.01 $11,598,573 ($610,064)
2Seventy Bio, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($446,174)
Catalent, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($167,160)
Enanta Pharmaceuticals Inc -- $0 $0 -- $0 $0 2.02 $256,050 ($126,993)
Clearside Biomedical, Inc. -- $0 $0 -- $0 $0 -- $50,300 $0
LIFECORE BIOMEDICAL, INC. \DE\ -- $0 $0 -- $0 $0 -- $97,580 $0
Repare Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($42,488)
Checkpoint Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,598,055)
Chimerix Inc -- $0 $0 -- $0 $0 0.00 $0 ($91,140)
Nuvectis Pharma, Inc. -- $0 $0 -- $0 $0 5.75 $129,305 ($22,478)
Aclaris Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $1,499,998 $0
Rhythm Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,948,121)
Abcellera Biologics Inc. -- $0 $0 -- $0 $0 -- $198,068 $0
Aprea Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $10,110 $0
Tvardi Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,365)
Altimmune, Inc. -- $0 $0 -- $0 $0 -- $57,780 $0
Elanco Animal Health Inc -- $0 $0 -- $0 $0 -- $483,558 $0
Generation Bio Co. -- $0 $0 -- $0 $0 -- $203,209 $0
Ibio, Inc. -- $0 $0 -- $0 $0 -- $654,995 $0
Optinose, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($58,362)
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($94,797)
Assembly Biosciences, Inc. -- $0 $0 -- $0 $0 3.26 $49,998 ($15,315)
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($1,319)
Synlogic, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,975)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 -- $69,950 $0
Alaunos Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,022)
Avalo Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $12,750 $0
Cue Biopharma, Inc. -- $0 $0 -- $0 $0 -- $30,900 $0
Arbutus Biopharma Corp -- $0 $0 -- $0 $0 0.00 $0 ($251,655)
Galera Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $499,979 $0
Vtv Therapeutics Inc. -- $0 $0 -- $0 $0 -- $83,812 $0
Prestige Consumer Healthcare Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,696,872)
Sarepta Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($205,400)
Veru Inc. -- $0 $0 -- $0 $0 -- $84,351 $0
MARINUS PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,733)
Vyne Therapeutics Inc. -- $0 $0 -- $0 $0 -- $43,800 $0
Marker Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $35,472 $0
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,501,298)
Edgewise Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $20,000,000 $0
Cytomx Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($47,888)
Prelude Therapeutics Inc -- $0 $0 -- $0 $0 -- $876,166 $0
Avenue Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($183)
Pfizer Inc -- $0 $0 -- $0 $0 8.13 $527,312 ($64,825)
Merck & Co., Inc. -- $0 $0 -- $0 $0 1.10 $1,577,424 ($1,436,352)
Therapeuticsmd, Inc. -- $0 $0 -- $0 $0 -- $2,809 $0
Verrica Pharmaceuticals Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,805)
Equillium, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($13,500)
Janux Therapeutics, Inc. -- $0 $0 -- $0 $0 5.36 $25,342,965 ($4,731,473)
Pds Biotechnology Corp -- $0 $0 -- $0 $0 -- $50,001 $0
Atai Life Sciences N.V. -- $0 $0 -- $0 $0 0.00 $0 ($246,038)
Ovid Therapeutics Inc. -- $0 $0 -- $0 $0 0.97 $4,971 ($5,141)
Revance Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($16,296)
PALVELLA THERAPEUTICS, INC. -- $0 $0 -- $0 $0 -- $152,517 $0
Opus Genetics, Inc. -- $0 $0 -- $0 $0 -- $208,592 $0
Forte Biosciences, Inc. -- $0 $0 -- $0 $0 -- $124,998 $0
Acurx Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $170,000 $0
Ventyx Biosciences, Inc. -- $0 $0 -- $0 $0 24.31 $1,260,462 ($51,860)
Nrx Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $46,800 $0
Pyxis Oncology, Inc. -- $0 $0 -- $0 $0 -- $10,900 $0
Atea Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.08 $81,498 ($1,023,475)
Rein Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $898 $0
Unity Biotechnology, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($145,942)
TALPHERA, INC. -- $0 $0 -- $0 $0 1109.04 $131,849 ($119)
Avadel Pharmaceuticals Plc -- $0 $0 -- $0 $0 -- $761,675 $0
Tango Therapeutics, Inc. -- $0 $0 -- $0 $0 0.52 $74,000 ($143,227)
Perspective Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $594,081 $0
Maravai Lifesciences Holdings, Inc. -- $0 $0 -- $0 $0 8.65 $1,087,625 ($125,750)
Rigel Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($424,179)
Promis Neurosciences Inc. -- $0 $0 -- $0 $0 -- $14,595 $0
Anebulo Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $10,000,000 $0
Benitec Biopharma Inc. -- $0 $0 -- $0 $0 -- $13,258,726 $0
Biohaven Ltd. -- $0 $0 -- $0 $0 -- $2,038,632 $0
Serina Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $17,745 $0
Entero Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($465)
BIOADAPTIVES, INC. -- $0 $0 -- $0 $0 -- $10,625 $0
Coya Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $106,393 $0
Bio Essence Corp -- $0 $0 -- $0 $0 0.00 $0 ($81,992)
ACELYRIN, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($68,902)
MIRA PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($133,649)
Kairos Pharma, LTD. -- $0 $0 -- $0 $0 -- $9,828 $0
Nika Pharmaceuticals, Inc -- $0 $0 -- $0 $0 0.00 $0 ($500,000)
Contineum Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($117,598)
IMPACT BIOMEDICAL INC. -- $0 $0 -- $0 $0 0.00 $5,173 ($4,209,761)
Septerna, Inc. -- $0 $0 -- $0 $0 -- $934,328 $0