Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 6/13/2025 10:04:30 PM
1 Month
Buy/Sell Ratio 1.12
52%
48%
Buy Sell
$56.75 M ($50.85) M
73 Insiders 119 Insiders
157 Transactions 175 Transactions
5/13/2025 to 6/13/2025
3 Month
Buy/Sell Ratio 1.16
53%
47%
Buy Sell
$140.72 M ($121.20) M
162 Insiders 269 Insiders
510 Transactions 447 Transactions
3/13/2025 to 6/13/2025
6 Month
Buy/Sell Ratio 0.60
37%
63%
Buy Sell
$356.58 M ($597.95) M
263 Insiders 562 Insiders
801 Transactions 1274 Transactions
12/13/2024 to 6/13/2025
12 Month
Buy/Sell Ratio 0.40
28%
72%
Buy Sell
$642.60 M ($1,611.35) M
420 Insiders 795 Insiders
1432 Transactions 2332 Transactions
6/13/2024 to 6/13/2025

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Janux Therapeutics, Inc.
$79,042,965 4
Zymeworks Inc.
$58,036,053 36
89Bio, Inc.
$49,999,994 1
Climb Bio, Inc.
$49,952,817 1
Tyra Biosciences, Inc.
$33,491,371 4
ALUMIS INC.
$26,477,312 3
Aurinia Pharmaceuticals Inc.
$23,535,126 6
Bicycle Therapeutics Plc
$21,230,385 2
Precigen, Inc.
$19,999,999 1
Akero Therapeutics, Inc.
$18,387,921 4

Most Insider Selling

12 months
Name Value Transactions
Beigene, Ltd.
($384,735,063) 2
Nuvalent, Inc.
($110,000,000) 1
MoonLake Immunotherapeutics
($100,003,200) 1
Nuvalent, Inc.
($97,750,000) 1
Dyne Therapeutics, Inc.
($97,727,621) 43
Roivant Sciences Ltd.
($51,232,227) 5
Abbvie Inc.
($32,666,600) 3
Bridgebio Pharma, Inc.
($30,243,415) 6
Vertex Pharmaceuticals Inc / Ma
($23,059,374) 3
Verona Pharma Plc
($20,341,919) 23

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Hcw Biologics Inc. 6 8
Avadel Pharmaceuticals Plc 6 7
Organon & Co. 6 6
Relmada Therapeutics, Inc. 5 13
Zomedica Corp. 5 6
Maia Biotechnology, Inc. 4 13
Immunome Inc. 4 11
Biohaven Ltd. 4 10
CalciMedica, Inc. 4 8
Rezolute, Inc. 4 8

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Apellis Pharmaceuticals, Inc. 12 32
Blueprint Medicines Corp 11 26
Xencor Inc 11 12
Vertex Pharmaceuticals Inc / Ma 10 32
Ptc Therapeutics, Inc. 9 34
Nuvalent, Inc. 9 19
Arrowhead Pharmaceuticals, Inc. 9 18
Catalent, Inc. 9 9
Dyne Therapeutics, Inc. 8 61
Insmed Inc 8 56

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Ardelyx, Inc. 3.13 $1,066,380 ($340,703) 9.18 $5,055,307 ($550,815) 2.77 $6,051,904 ($2,181,124)
Arcutis Biotherapeutics, Inc. 1.70 $220,076 ($129,656) 0.13 $338,428 ($2,613,469) 0.10 $372,452 ($3,893,682)
Aspire Biopharma Holdings, Inc. 1.00 $7,800 ($7,800) 1.00 $7,800 ($7,800) 1.00 $7,800 ($7,800)
Insmed Inc 0.04 $201,694 ($4,485,343) 0.01 $201,694 ($40,281,998) 0.00 $201,694 ($40,968,405)
Verona Pharma Plc 0.00 $0 ($16,589,403) 0.00 $0 ($18,265,688) 0.01 $579,386 ($43,534,690)
Corcept Therapeutics Inc 0.00 $0 ($5,068,858) 0.00 $0 ($11,647,972) 0.00 $0 ($11,985,367)
Eton Pharmaceuticals, Inc. 0.00 $0 ($3,592,611) 0.00 $0 ($3,592,611) 0.00 $0 ($3,592,611)
Catalyst Pharmaceuticals, Inc. 0.00 $0 ($3,580,787) 0.00 $0 ($4,277,170) 0.00 $0 ($7,330,070)
Akero Therapeutics, Inc. 0.00 $0 ($2,659,245) 1.45 $18,387,921 ($12,719,553) 1.28 $18,387,921 ($14,335,490)
Beigene, Ltd. 0.00 $0 ($2,353,290) 0.00 $0 ($196,889,855) 0.00 $0 ($400,796,204)
Eli Lilly & Co 0.00 $0 ($1,652,960) 0.00 $0 ($6,787,265) 0.00 $0 ($8,222,807)
Axsome Therapeutics, Inc. 0.00 $0 ($1,105,848) 0.00 $0 ($1,105,848) 0.00 $0 ($1,105,848)
Amneal Pharmaceuticals, Inc. 0.00 $0 ($825,018) 0.00 $0 ($7,448,271) 0.00 $0 ($9,539,400)
Cytokinetics Inc 0.00 $0 ($748,127) 0.00 $0 ($8,063,532) 0.00 $0 ($9,882,313)
Enliven Therapeutics, Inc. 0.00 $0 ($600,132) 0.00 $0 ($2,113,285) 0.00 $0 ($8,643,415)
Abeona Therapeutics Inc. 0.00 $0 ($591,841) 0.00 $0 ($753,261) 0.00 $0 ($986,478)
Blueprint Medicines Corp 0.00 $0 ($568,590) 0.00 $0 ($8,520,465) 0.00 $0 ($9,708,395)
Verastem, Inc. 0.00 $0 ($567,637) 0.00 $0 ($640,195) 0.00 $0 ($661,895)
Pacira Biosciences, Inc. 0.00 $0 ($523,426) 0.00 $0 ($539,599) 0.33 $215,684 ($654,973)
Disc Medicine, Inc. 0.00 $0 ($483,928) 0.00 $0 ($41,692,680) 0.33 $14,000,076 ($41,839,680)
Acadia Pharmaceuticals Inc 0.00 $0 ($454,634) 0.00 $0 ($544,307) 0.00 $0 ($1,323,801)
Ocular Therapeutix, Inc 0.00 $0 ($320,320) 0.11 $69,600 ($658,755) 0.06 $69,600 ($1,118,934)
Mannkind Corp 0.00 $0 ($319,825) 0.00 $0 ($846,298) 0.00 $0 ($2,547,016)
Ani Pharmaceuticals Inc 0.00 $0 ($294,722) 0.00 $0 ($1,132,458) 0.00 $0 ($9,102,663)
Zai Lab Ltd 0.00 $0 ($288,540) 0.00 $0 ($2,180,892) 0.00 $0 ($2,593,646)
Theravance Biopharma, Inc. 0.00 $0 ($264,000) 0.00 $0 ($336,000) 0.00 $0 ($408,000)
Alkermes Plc. 0.00 $0 ($210,143) 0.00 $0 ($210,143) 0.00 $0 ($1,403,137)
Wave Life Sciences Ltd. 0.00 $0 ($208,500) 0.00 $0 ($208,500) 0.00 $0 ($2,733,150)
Cryoport, Inc. 0.00 $0 ($191,271) 0.00 $0 ($288,589) 0.00 $0 ($331,649)
Mineralys Therapeutics, Inc. 0.00 $0 ($173,774) 38.58 $29,099,992 ($754,207) 3.09 $29,099,992 ($9,430,798)
Ligand Pharmaceuticals Inc 0.00 $0 ($161,271) 1.18 $1,156,546 ($981,270) 0.29 $1,400,027 ($4,897,340)
GYRE THERAPEUTICS, INC. 0.00 $0 ($160,569) 0.00 $0 ($1,546,917) 0.00 $0 ($1,546,917)
Mirum Pharmaceuticals, Inc. 0.00 $0 ($155,091) 0.15 $280,117 ($1,911,152) 0.15 $293,981 ($1,911,152)
Zoetis Inc. 0.00 $0 ($110,840) 0.00 $0 ($367,289) 0.00 $0 ($367,289)
Jazz Pharmaceuticals Plc 0.00 $0 ($108,950) 2.63 $9,993,082 ($3,798,672) 2.10 $9,993,082 ($4,767,664)
Biomarin Pharmaceutical Inc 0.00 $0 ($105,928) 0.00 $0 ($809,527) 0.00 $0 ($1,224,111)
Neurogene Inc. 0.00 $0 ($103,003) 0.00 $0 ($179,250) 8.15 $1,460,400 ($179,250)
Rocket Pharmaceuticals, Inc. 0.00 $0 ($84,330) 0.40 $200,765 ($507,362) 0.16 $200,765 ($1,271,825)
Stoke Therapeutics, Inc. 0.00 $0 ($82,342) 0.00 $0 ($609,938) 0.00 $0 ($1,331,358)
Rapport Therapeutics, Inc. 0.00 $0 ($81,262) 0.64 $162,238 ($254,777) 2.00 $510,541 ($254,777)
KALA BIO, Inc. 0.00 $0 ($80,496) 0.00 $0 ($153,027) 0.00 $0 ($317,524)
Dyne Therapeutics, Inc. 0.00 $0 ($74,066) 0.00 $0 ($274,253) 0.00 $264,304 ($99,614,659)
Oric Pharmaceuticals, Inc. 0.00 $0 ($65,038) 0.00 $0 ($65,038) 0.00 $0 ($65,038)
Emergent Biosolutions Inc. 0.00 $0 ($49,417) 1.13 $349,800 ($310,767) 0.46 $349,800 ($754,533)
Akebia Therapeutics, Inc. 0.00 $0 ($47,069) 0.00 $0 ($734,287) 0.00 $0 ($734,287)
Longeveron Inc. 0.00 $0 ($36,757) 0.00 $0 ($36,757) 0.00 $0 ($39,345)
Corbus Pharmaceuticals Holdings, Inc. 0.00 $0 ($30,561) 0.00 $0 ($160,802) 0.00 $0 ($160,802)
Nektar Therapeutics 0.00 $0 ($29,424) 0.00 $0 ($299,487) 0.00 $0 ($388,731)
Vertex Pharmaceuticals Inc / Ma 0.00 $0 ($22,084) 0.00 $0 ($19,147,280) 0.00 $0 ($50,505,392)
Kronos Bio, Inc. 0.00 $0 ($21,554) 0.00 $0 ($21,554) 34.04 $733,801 ($21,554)
Kura Oncology, Inc. 0.00 $0 ($19,069) 0.00 $0 ($198,226) 0.00 $0 ($206,659)
Amphastar Pharmaceuticals, Inc. 0.00 $0 ($12,835) 0.00 $0 ($67,053) 0.00 $0 ($353,639)
Ironwood Pharmaceuticals Inc 0.00 $0 ($9,231) 0.00 $0 ($437,564) 0.00 $0 ($559,900)
Igm Biosciences, Inc. 0.00 $0 ($2,090) 0.00 $0 ($67,203) 0.00 $0 ($284,205)
Xenon Pharmaceuticals Inc. 0.00 $0 ($91) 0.00 $0 ($91) 0.00 $0 ($91)
Rafael Holdings, Inc. -- $16,742,985 $0 -- $16,742,985 $0 -- $16,742,985 $0
Bausch Health Companies Inc. -- $14,700,257 $0 -- $14,700,257 $0 169.55 $14,700,257 ($86,702)
Tyra Biosciences, Inc. -- $13,655,305 $0 24.28 $13,655,305 ($562,435) 4.25 $33,643,326 ($7,913,166)
Centessa Pharmaceuticals Plc -- $5,865,242 $0 1.14 $5,865,242 ($5,125,298) 0.70 $5,865,242 ($8,383,035)
Organogenesis Holdings Inc. -- $725,290 $0 4.93 $725,290 ($147,027) 0.57 $725,290 ($1,273,959)
Zymeworks Inc. -- $635,586 $0 -- $58,036,053 $0 -- $58,036,053 $0
Relmada Therapeutics, Inc. -- $461,311 $0 -- $461,311 $0 -- $1,104,156 $0
Syndax Pharmaceuticals Inc -- $241,896 $0 0.72 $241,896 ($336,173) 0.79 $266,933 ($336,173)
Immunic, Inc. -- $230,234 $0 -- $230,234 $0 -- $330,603 $0
Evolus, Inc. -- $189,000 $0 0.07 $189,000 ($2,574,301) 0.07 $189,000 ($2,712,627)
Hcw Biologics Inc. -- $170,002 $0 -- $3,045,056 $0 -- $3,045,056 $0
Werewolf Therapeutics, Inc. -- $159,288 $0 -- $487,188 $0 -- $487,188 $0
NEONC TECHNOLOGIES HOLDINGS, INC. -- $138,117 $0 -- $207,889 $0 -- $207,889 $0
Vanda Pharmaceuticals Inc. -- $128,467 $0 -- $472,136 $0 12.05 $472,136 ($39,190)
AYTU BIOPHARMA, INC -- $124,998 $0 -- $144,498 $0 -- $144,498 $0
Context Therapeutics Inc. -- $107,086 $0 -- $107,086 $0 -- $107,086 $0
Organon & Co. -- $100,591 $0 -- $651,626 $0 -- $651,626 $0
Regulus Therapeutics Inc. -- $95,852 $0 0.55 $170,899 ($310,669) 0.57 $178,179 ($310,669)
Tonix Pharmaceuticals Holding Corp. -- $86,200 $0 -- $86,200 $0 -- $86,200 $0
Sellas Life Sciences Group, Inc. -- $84,600 $0 -- $84,600 $0 -- $84,600 $0
AEON Biopharma, Inc. -- $84,550 $0 -- $84,550 $0 -- $84,550 $0
Maia Biotechnology, Inc. -- $50,000 $0 -- $452,498 $0 -- $1,183,624 $0
Immunome Inc. -- $46,900 $0 -- $2,430,579 $0 -- $3,838,198 $0
Aerovate Therapeutics, Inc. -- $44,400 $0 -- $44,400 $0 -- $1,594,344 $0
CervoMed Inc. -- $35,811 $0 -- $35,811 $0 -- $53,971 $0
Phathom Pharmaceuticals, Inc. -- $35,528 $0 1.02 $261,173 ($257,224) 0.53 $441,505 ($832,371)
Zomedica Corp. -- $32,970 $0 -- $312,256 $0 -- $454,896 $0
Renovorx, Inc. -- $29,400 $0 -- $148,790 $0 -- $148,790 $0
Anixa Biosciences Inc -- $28,500 $0 -- $214,541 $0 -- $350,539 $0
CalciMedica, Inc. -- $28,485 $0 -- $28,485 $0 -- $1,373,230 $0
Phio Pharmaceuticals Corp. -- $27,011 $0 -- $27,011 $0 -- $27,011 $0
Io Biotech, Inc. -- $20,884 $0 -- $75,761 $0 -- $75,761 $0
Savara Inc -- $20,825 $0 1.50 $437,075 ($290,675) 2.70 $783,747 ($290,675)
An2 Therapeutics, Inc. -- $20,798 $0 0.88 $20,798 ($23,610) 21.35 $504,135 ($23,610)
Accustem Sciences Inc. -- $18,462 $0 -- $160,139 $0 -- $160,139 $0
FibroBiologics, Inc. -- $16,800 $0 -- $16,800 $0 -- $52,069 $0
60 DEGREES PHARMACEUTICALS, INC. -- $14,410 $0 -- $17,310 $0 -- $140,433 $0
Apimeds Pharmaceuticals US, Inc. -- $14,378 $0 -- $107,074 $0 -- $107,074 $0
Pepgen Inc. -- $10,393 $0 14.42 $71,668 ($4,971) 14.42 $71,668 ($4,971)
MetaVia Inc. -- $9,940 $0 -- $9,940 $0 -- $9,940 $0
Atossa Therapeutics, Inc. -- $9,887 $0 -- $16,887 $0 -- $16,887 $0
Silo Pharma, Inc. -- $4,329 $0 -- $4,329 $0 -- $11,051 $0
Cumberland Pharmaceuticals Inc -- $4,122 $0 -- $24,830 $0 -- $58,769 $0
Tharimmune, Inc. -- $1,001 $0 -- $10,753 $0 -- $35,720 $0
Bridgebio Pharma, Inc. -- $0 $0 0.00 $0 ($33,518,998) 0.00 $0 ($34,225,961)
Arrowhead Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($6,179,759) 0.00 $0 ($6,417,239)
Arvinas, Inc. -- $0 $0 0.00 $0 ($839,578) 0.00 $0 ($845,974)
Apellis Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,913,781) 0.00 $0 ($5,906,059)
Aurinia Pharmaceuticals Inc. -- $0 $0 2.14 $12,713,126 ($5,946,646) 3.89 $23,535,126 ($6,043,548)
Greenwich Lifesciences, Inc. -- $0 $0 -- $366,319 $0 -- $567,349 $0
Nurix Therapeutics, Inc. -- $0 $0 0.00 $0 ($154,630) 0.00 $0 ($1,219,876)
Processa Pharmaceuticals, Inc. -- $0 $0 -- $9,889 $0 -- $9,889 $0
Puma Biotechnology, Inc. -- $0 $0 0.00 $0 ($195,840) 0.00 $0 ($509,917)
Avid Bioservices, Inc. -- $0 $0 0.00 $0 ($2,785,375) 0.00 $0 ($2,785,375)
Zentalis Pharmaceuticals, Inc. -- $0 $0 3.86 $252,786 ($65,472) 3.58 $252,786 ($70,569)
Harmony Biosciences Holdings, Inc. -- $0 $0 0.00 $0 ($227,386) 0.00 $0 ($1,501,932)
Y-Mabs Therapeutics, Inc. -- $0 $0 0.00 $0 ($76,905) 0.00 $0 ($1,415,005)
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,121,355) 0.00 $0 ($2,565,761)
Travere Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,449,770) 0.00 $0 ($2,887,138)
Ptc Therapeutics, Inc. -- $0 $0 0.00 $0 ($3,529,191) 0.00 $0 ($3,606,392)
United Therapeutics Corp -- $0 $0 0.00 $0 ($90,720) 0.00 $0 ($1,683,958)
Cartesian Therapeutics, Inc. -- $0 $0 6.93 $4,225,046 ($610,064) 26.37 $16,089,335 ($610,064)
Tg Therapeutics, Inc. -- $0 $0 0.00 $0 ($629,382) 0.00 $0 ($2,458,946)
Amylyx Pharmaceuticals, Inc. -- $0 $0 0.08 $37,005 ($464,463) 0.69 $464,763 ($677,713)
2Seventy Bio, Inc. -- $0 $0 0.00 $0 ($425,598) 0.00 $0 ($488,966)
Galectin Therapeutics Inc -- $0 $0 -- $34,883 $0 -- $81,570 $0
Enanta Pharmaceuticals Inc -- $0 $0 -- $256,050 $0 1.18 $256,050 ($216,583)
Clearside Biomedical, Inc. -- $0 $0 -- $13,800 $0 -- $75,210 $0
Entrada Therapeutics, Inc. -- $0 $0 0.00 $0 ($19,035) 0.00 $0 ($999,640)
LIFECORE BIOMEDICAL, INC. \DE\ -- $0 $0 -- $97,580 $0 -- $5,473,959 $0
Repare Therapeutics Inc. -- $0 $0 0.00 $0 ($42,488) 0.00 $0 ($42,488)
Uniqure N.V. -- $0 $0 0.00 $0 ($1,034,213) 0.00 $0 ($1,102,016)
89Bio, Inc. -- $0 $0 308.58 $50,099,844 ($162,357) 129.20 $50,302,794 ($389,352)
Ultragenyx Pharmaceutical Inc. -- $0 $0 0.00 $0 ($7,333,651) 0.00 $0 ($10,290,600)
Bolt Biotherapeutics, Inc. -- $0 $0 -- $2,482 $0 -- $2,482 $0
Checkpoint Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,598,055) 0.00 $0 ($4,675,363)
Chimerix Inc -- $0 $0 0.00 $0 ($91,140) 0.00 $0 ($92,205)
Abbvie Inc. -- $0 $0 0.00 $0 ($29,625,038) 0.00 $0 ($42,028,618)
Nuvectis Pharma, Inc. -- $0 $0 -- $20,925 $0 5.75 $129,305 ($22,478)
Lifevantage Corp -- $0 $0 0.04 $14,645 ($364,620) 0.08 $28,626 ($364,620)
Karyopharm Therapeutics Inc. -- $0 $0 0.00 $0 ($176,010) 0.00 $0 ($209,416)
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $0 ($15,277,900) 0.00 $0 ($26,610,888)
Alnylam Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($4,662,470) 0.00 $10,363 ($13,652,750)
Vera Therapeutics, Inc. -- $0 $0 0.00 $0 ($546,914) 0.00 $0 ($2,539,065)
Rhythm Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,948,121) 0.00 $0 ($1,948,121)
Nuvalent, Inc. -- $0 $0 0.00 $0 ($3,262,672) 0.00 $0 ($216,220,091)
Abbott Laboratories -- $0 $0 0.00 $0 ($1,223,161) 0.00 $0 ($1,226,261)
Xeris Biopharma Holdings, Inc. -- $0 $0 0.00 $0 ($217,244) 0.09 $20,281 ($217,244)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,167,150) 0.00 $0 ($41,773,210)
Bristol Myers Squibb Co -- $0 $0 111.82 $412,284 ($3,687) 12.02 $512,340 ($42,617)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($2,459,665) 0.00 $0 ($3,584,776)
Abcellera Biologics Inc. -- $0 $0 -- $198,068 $0 -- $198,068 $0
Aprea Therapeutics, Inc. -- $0 $0 -- $10,110 $0 5.95 $176,052 ($29,583)
Tvardi Therapeutics, Inc. -- $0 $0 0.00 $0 ($5,301) 0.00 $0 ($7,817)
Altimmune, Inc. -- $0 $0 -- $57,780 $0 -- $57,780 $0
Elanco Animal Health Inc -- $0 $0 -- $483,558 $0 -- $1,836,142 $0
Dynavax Technologies Corp -- $0 $0 0.00 $0 ($661,866) 0.00 $0 ($661,866)
Xencor Inc -- $0 $0 0.00 $0 ($594,003) 0.00 $0 ($894,256)
Perrigo Co Plc -- $0 $0 -- $94,850 $0 0.05 $94,850 ($2,092,745)
Generation Bio Co. -- $0 $0 -- $203,209 $0 11.04 $203,209 ($18,410)
Ibio, Inc. -- $0 $0 -- $654,995 $0 -- $654,995 $0
Viatris Inc -- $0 $0 -- $536,262 $0 0.05 $536,262 ($10,089,751)
Optinose, Inc. -- $0 $0 0.00 $0 ($58,362) 0.00 $0 ($287,300)
Arcus Biosciences, Inc. -- $0 $0 7.47 $402,665 ($53,910) 5.21 $402,665 ($77,304)
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($73,348) 0.00 $0 ($124,529)
Applied Therapeutics, Inc. -- $0 $0 0.00 $0 ($94,797) 0.00 $0 ($5,017,956)
XOMA Royalty Corp -- $0 $0 -- $709,728 $0 -- $709,728 $0
Assembly Biosciences, Inc. -- $0 $0 3.41 $49,998 ($14,664) 1.09 $49,998 ($45,693)
Alzamend Neuro, Inc. -- $0 $0 3.40 $21,072 ($6,196) 3.45 $21,372 ($6,196)
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,520) 0.00 $0 ($2,520)
Ionis Pharmaceuticals Inc -- $0 $0 0.30 $658,979 ($2,173,299) 0.21 $658,979 ($3,131,096)
Synlogic, Inc. -- $0 $0 0.00 $0 ($2,975) 0.00 $0 ($3,086)
Nuvation Bio Inc. -- $0 $0 -- $987,205 $0 21.64 $3,524,939 ($162,883)
Annexon, Inc. -- $0 $0 0.00 $0 ($126,438) 0.33 $89,664 ($274,048)
Liquidia Corp -- $0 $0 0.00 $0 ($1,463,495) 1.53 $2,999,994 ($1,954,411)
Schrodinger, Inc. -- $0 $0 0.00 $0 ($230,658) 0.00 $0 ($257,884)
Alaunos Therapeutics, Inc. -- $0 $0 0.00 $0 ($6,022) 0.00 $0 ($6,022)
Bespoke Extracts, Inc. -- $0 $0 -- $2,770 $0 -- $5,370 $0
Bicycle Therapeutics Plc -- $0 $0 12.12 $7,670,900 ($632,893) 23.05 $21,230,385 ($920,949)
Fibrogen Inc -- $0 $0 -- $155,703 $0 -- $155,703 $0
Protagonist Therapeutics, Inc -- $0 $0 0.00 $0 ($502,383) 0.00 $0 ($580,490)
Cue Biopharma, Inc. -- $0 $0 -- $30,900 $0 -- $30,900 $0
Nkarta, Inc. -- $0 $0 0.00 $0 ($107,547) 0.00 $0 ($155,088)
Kiniksa Pharmaceuticals International, plc -- $0 $0 0.00 $0 ($370,475) 0.00 $0 ($370,475)
Arbutus Biopharma Corp -- $0 $0 0.00 $0 ($251,655) 0.00 $0 ($251,655)
Phibro Animal Health Corp -- $0 $0 -- $110,500 $0 -- $210,600 $0
Anaptysbio, Inc -- $0 $0 -- $1,099,642 $0 24.34 $1,099,642 ($45,182)
Galera Therapeutics, Inc. -- $0 $0 -- $499,979 $0 103.62 $499,979 ($4,825)
Cellectar Biosciences, Inc. -- $0 $0 -- $8,400 $0 -- $8,400 $0
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($151,020) 0.00 $0 ($1,696,872)
Veru Inc. -- $0 $0 -- $84,351 $0 -- $84,351 $0
MARINUS PHARMACEUTICALS, INC. -- $0 $0 0.00 $0 ($1,733) 0.19 $6,526 ($34,622)
Alx Oncology Holdings Inc -- $0 $0 0.00 $0 ($27,952) 0.34 $46,404 ($137,584)
Vyne Therapeutics Inc. -- $0 $0 -- $43,800 $0 -- $43,800 $0
Avidity Biosciences, Inc. -- $0 $0 0.00 $0 ($5,398,236) 0.00 $0 ($11,504,671)
Marker Therapeutics, Inc. -- $0 $0 -- $35,472 $0 -- $35,472 $0
Pliant Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,501,298) 0.00 $0 ($2,420,272)
Edgewise Therapeutics, Inc. -- $0 $0 -- $20,000,000 $0 98.72 $20,000,000 ($202,603)
Design Therapeutics, Inc. -- $0 $0 0.00 $0 ($23,864) 0.00 $0 ($3,487,078)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($47,888) 0.00 $0 ($47,888)
Prelude Therapeutics Inc -- $0 $0 -- $876,166 $0 -- $876,166 $0
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($11,748) 0.00 $0 ($11,748)
Cogent Biosciences, Inc. -- $0 $0 -- $332,412 $0 -- $332,412 $0
Pfizer Inc -- $0 $0 7.70 $499,072 ($64,825) 2.48 $527,312 ($212,539)
Merck & Co., Inc. -- $0 $0 1.10 $1,577,424 ($1,436,352) 1.10 $1,577,424 ($1,436,352)
Therapeuticsmd, Inc. -- $0 $0 -- $2,809 $0 -- $11,946 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 0.09 $81,976 ($919,975) 0.25 $226,199 ($919,975)
Opko Health, Inc. -- $0 $0 -- $2,268,065 $0 -- $4,296,381 $0
Verrica Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($2,805) 0.00 $0 ($1,080,006)
Equillium, Inc. -- $0 $0 0.00 $0 ($6,500) 0.00 $0 ($86,433)
Viking Therapeutics, Inc. -- $0 $0 0.00 $29,943 ($12,781,795) 0.00 $29,943 ($21,404,523)
Janux Therapeutics, Inc. -- $0 $0 10.40 $25,342,965 ($2,436,594) 10.60 $79,042,965 ($7,459,389)
Pds Biotechnology Corp -- $0 $0 -- $50,001 $0 -- $50,001 $0
Atai Life Sciences N.V. -- $0 $0 0.00 $0 ($246,038) 0.00 $0 ($246,038)
Palatin Technologies Inc -- $0 $0 -- $10,180 $0 1.23 $10,180 ($8,274)
Ovid Therapeutics Inc. -- $0 $0 0.97 $4,971 ($5,141) 0.97 $4,971 ($5,141)
Rezolute, Inc. -- $0 $0 -- $202,333 $0 -- $5,473,852 $0
PALVELLA THERAPEUTICS, INC. -- $0 $0 -- $152,517 $0 -- $152,517 $0
Opus Genetics, Inc. -- $0 $0 -- $97,600 $0 -- $208,592 $0
Acurx Pharmaceuticals, Inc. -- $0 $0 -- $170,000 $0 -- $170,000 $0
Ventyx Biosciences, Inc. -- $0 $0 5.80 $300,573 ($51,860) 24.31 $1,260,462 ($51,860)
Nrx Pharmaceuticals, Inc. -- $0 $0 -- $46,800 $0 -- $46,800 $0
Immix Biopharma, Inc. -- $0 $0 -- $104,358 $0 -- $194,098 $0
Atea Pharmaceuticals, Inc. -- $0 $0 -- $81,498 $0 0.06 $81,498 ($1,318,774)
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($235,387) 0.00 $0 ($345,732)
Geron Corp -- $0 $0 -- $221,880 $0 -- $221,880 $0
Madrigal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,433,430) 0.00 $0 ($7,529,111)
Oncotelic Therapeutics, Inc. -- $0 $0 -- $9,712 $0 -- $28,338 $0
Rockwell Medical, Inc. -- $0 $0 0.00 $0 ($18,049) 0.00 $0 ($100,088)
Unity Biotechnology, Inc. -- $0 $0 0.00 $0 ($145,017) 0.00 $0 ($149,576)
TALPHERA, INC. -- $0 $0 -- $125,000 $0 1229.83 $146,208 ($119)
Avadel Pharmaceuticals Plc -- $0 $0 -- $355,308 $0 -- $761,675 $0
Tango Therapeutics, Inc. -- $0 $0 0.00 $0 ($143,227) 0.52 $74,000 ($143,227)
Geovax Labs, Inc. -- $0 $0 -- $33,883 $0 -- $49,483 $0
Earth Science Tech, Inc. -- $0 $0 -- $235,620 $0 -- $422,232 $0
Maravai Lifesciences Holdings, Inc. -- $0 $0 0.00 $0 ($125,750) 8.65 $1,087,625 ($125,750)
Terns Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($213,457) 3.53 $5,124,566 ($1,450,317)
Rigel Pharmaceuticals Inc -- $0 $0 0.00 $0 ($424,179) 0.00 $0 ($424,179)
Promis Neurosciences Inc. -- $0 $0 -- $14,595 $0 -- $282,837 $0
Lyell Immunopharma, Inc. -- $0 $0 -- $447,931 $0 -- $447,931 $0
Anebulo Pharmaceuticals, Inc. -- $0 $0 -- $10,000,000 $0 -- $10,000,000 $0
Benitec Biopharma Inc. -- $0 $0 -- $12,438,910 $0 -- $13,258,726 $0
Pasithea Therapeutics Corp. -- $0 $0 0.00 $0 ($792) 0.00 $0 ($792)
Biohaven Ltd. -- $0 $0 -- $2,038,632 $0 -- $6,280,010 $0
Journey Medical Corp -- $0 $0 0.00 $0 ($887,229) 0.00 $0 ($960,128)
Serina Therapeutics, Inc. -- $0 $0 -- $17,745 $0 -- $441,627 $0
Quoin Pharmaceuticals, Ltd. -- $0 $0 -- $600,000 $0 -- $680,858 $0
Entero Therapeutics, Inc. -- $0 $0 0.00 $0 ($465) 0.00 $0 ($2,721)
NewAmsterdam Pharma Co N.V. -- $0 $0 -- $109,724 $0 -- $294,715 $0
GENELUX CORP -- $0 $0 0.00 $0 ($145,842) 0.00 $0 ($182,531)
BullFrog AI Holdings, Inc. -- $0 $0 0.00 $0 ($74,094) 0.00 $0 ($287,295)
ACELYRIN, Inc. -- $0 $0 0.00 $0 ($68,902) 0.00 $0 ($68,909)
Mural Oncology plc -- $0 $0 0.00 $0 ($92,843) 0.18 $32,071 ($178,849)
Nika Pharmaceuticals, Inc -- $0 $0 0.00 $0 ($500,000) 0.00 $0 ($500,000)
ALUMIS INC. -- $0 $0 -- $1,909,889 $0 -- $26,909,889 $0
IMPACT BIOMEDICAL INC. -- $0 $0 0.00 $0 ($4,209,761) 0.00 $5,173 ($4,209,761)
Zenas Biopharma, Inc. -- $0 $0 -- $244,350 $0 -- $2,472,186 $0
Mbx Biosciences, Inc. -- $0 $0 -- $4,621,323 $0 -- $4,621,323 $0
Septerna, Inc. -- $0 $0 -- $934,328 $0 -- $934,328 $0
Emmaus Life Sciences, Inc. -- $0 $0 -- $0 $0 -- $800 $0
Precigen, Inc. -- $0 $0 -- $0 $0 -- $20,049,999 $0
G1 Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($42,917)
Day One Biopharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,922,637)
Kezar Life Sciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($3,879)
Regeneron Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($9,544,884)
Arcturus Therapeutics Holdings Inc. -- $0 $0 -- $0 $0 0.00 $0 ($249,121)
Syros Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 1.07 $321,920 ($300,686)
Keros Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($22,005,000)
Tempest Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $100,001 $0
Catalent, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,474,140)
Olema Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,290,968)
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $100,600 $0
Shattuck Labs, Inc. -- $0 $0 -- $0 $0 -- $126,999 $0
Clene Inc. -- $0 $0 -- $0 $0 -- $583,390 $0
Eyenovia, Inc. -- $0 $0 -- $0 $0 -- $42,577 $0
Aclaris Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $1,499,998 $0
Agios Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,179,076)
Vaccinex, Inc. -- $0 $0 -- $0 $0 -- $1,316,317 $0
Imunon, Inc. -- $0 $0 -- $0 $0 -- $79,730 $0
Roivant Sciences Ltd. -- $0 $0 -- $0 $0 0.00 $0 ($57,098,536)
Glycomimetics Inc -- $0 $0 -- $0 $0 -- $83,159 $0
Spyre Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($779,316)
Cingulate Inc. -- $0 $0 -- $0 $0 0.00 $0 ($841)
Gossamer Bio, Inc. -- $0 $0 -- $0 $0 257.45 $324,442 ($1,260)
Johnson & Johnson -- $0 $0 -- $0 $0 -- $147,220 $0
Protokinetix, Inc. -- $0 $0 -- $0 $0 -- $51,000 $0
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($1,319)
Lumos Pharma, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,426)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 -- $69,950 $0
KIORA PHARMACEUTICALS INC -- $0 $0 -- $0 $0 -- $54,540 $0
Avalo Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $12,750 $0
Bioxcel Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($18,173)
Amarin Corp Plc\Uk -- $0 $0 -- $0 $0 -- $102,400 $0
Aquestive Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($214)
ALT5 Sigma Corp -- $0 $0 -- $0 $0 -- $19,278 $0
Monopar Therapeutics -- $0 $0 -- $0 $0 -- $72,736 $0
Vtv Therapeutics Inc. -- $0 $0 -- $0 $0 -- $83,812 $0
Allakos Inc. -- $0 $0 -- $0 $0 0.00 $0 ($87,935)
Essa Pharma Inc. -- $0 $0 -- $0 $0 0.00 $0 ($20,903)
IGC Pharma, Inc. -- $0 $0 -- $0 $0 -- $200,000 $0
Sarepta Therapeutics, Inc. -- $0 $0 -- $0 $0 4.82 $4,955,728 ($1,027,499)
Pmv Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($15,200)
Fortress Biotech, Inc. -- $0 $0 -- $0 $0 -- $1,437,305 $0
Supernus Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($316,434)
Avenue Therapeutics, Inc. -- $0 $0 -- $0 $0 6.84 $1,250 ($183)
Cormedix Inc. -- $0 $0 -- $0 $0 -- $14,985 $0
Aridis Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -- $100,000 $0
Climb Bio, Inc. -- $0 $0 -- $0 $0 16.07 $49,952,817 ($3,108,685)
Revance Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($16,296)
Forte Biosciences, Inc. -- $0 $0 -- $0 $0 -- $124,998 $0
Pyxis Oncology, Inc. -- $0 $0 -- $0 $0 -- $10,900 $0
Aldeyra Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($127,288)
Hoth Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $16,750 $0
Rein Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $898 $0
Skye Bioscience, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,646,785)
Cassava Sciences Inc -- $0 $0 -- $0 $0 0.00 $0 ($15,480)
MoonLake Immunotherapeutics -- $0 $0 -- $0 $0 0.00 $0 ($109,189,320)
Foghorn Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($190,000)
Scynexis Inc -- $0 $0 -- $0 $0 -- $27,400 $0
Gain Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $85,154 $0
Lexaria Bioscience Corp. -- $0 $0 -- $0 $0 12.02 $123,400 ($10,268)
Whitehawk Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($182,887)
Rani Therapeutics Holdings, Inc. -- $0 $0 -- $0 $0 -- $49,967 $0
ADC Therapeutics SA -- $0 $0 -- $0 $0 0.00 $0 ($92,616)
CONDUIT PHARMACEUTICALS INC. -- $0 $0 -- $0 $0 0.00 $0 ($4,592,487)
Mereo Biopharma Group plc -- $0 $0 -- $0 $0 0.00 $0 ($2,315,682)
Flora Growth Corp. -- $0 $0 -- $0 $0 -- $30,759 $0
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 -- $0 $0 0.00 $0 ($562,305)
BIOADAPTIVES, INC. -- $0 $0 -- $0 $0 -- $10,625 $0
Coya Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $106,393 $0
Bio Essence Corp -- $0 $0 -- $0 $0 0.00 $0 ($2,492,803)
Sagimet Biosciences Inc. -- $0 $0 -- $0 $0 0.00 $0 ($178,175)
MIRA PHARMACEUTICALS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($133,649)
Kairos Pharma, LTD. -- $0 $0 -- $0 $0 -- $9,828 $0
Alto Neuroscience, Inc. -- $0 $0 -- $0 $0 -- $190,833 $0
Contineum Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($117,598)
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($85,024)
Bioage Labs, Inc. -- $0 $0 -- $0 $0 -- $4,430,395 $0