Industry - Pharmaceutical Preparations

  1. All Sectors
  2. Manufacturing
  3. Chemicals
Latest data: 8/4/2026 10:01:49 PM
1 Month
Buy/Sell Ratio 0.22
17%
83%
Buy Sell
$22.83 M ($105.19) M
22 Insiders 86 Insiders
38 Transactions 125 Transactions
7/4/2026 to 8/4/2026
3 Month
Buy/Sell Ratio 0.41
28%
72%
Buy Sell
$246.24 M ($606.92) M
105 Insiders 359 Insiders
184 Transactions 677 Transactions
5/4/2026 to 8/4/2026
6 Month
Buy/Sell Ratio 0.36
26%
74%
Buy Sell
$421.09 M ($1,174.59) M
203 Insiders 600 Insiders
386 Transactions 1455 Transactions
2/4/2026 to 8/4/2026
12 Month
Buy/Sell Ratio 0.50
33%
67%
Buy Sell
$1,172.75 M ($2,337.45) M
379 Insiders 858 Insiders
898 Transactions 2812 Transactions
8/4/2025 to 8/4/2026

Monthly Buy and Sell Value

Monthly Buy/Sell Ratio

Most Insider Buying

12 months
Name Value Transactions
Bausch Health Companies Inc.
$333,757,793 4
Madrigal Pharmaceuticals, Inc.
$61,921,024 3
Summit Therapeutics Inc.
$57,931,939 5
Summit Therapeutics Inc.
$57,931,939 5
Wave Life Sciences Ltd.
$54,631,065 4
Mineralys Therapeutics, Inc.
$38,762,782 3
CRESCENT BIOPHARMA, INC.
$30,612,625 2
Pepgen Inc.
$30,000,000 1
Viridian Therapeutics, Inc.\De
$29,999,980 2
Aurinia Pharmaceuticals Inc.
$27,480,033 7

Most Insider Selling

12 months
Name Value Transactions
Roivant Sciences Ltd.
($154,472,307) 10
Roivant Sciences Ltd.
($147,382,307) 9
Cogent Biosciences, Inc.
($127,400,000) 1
Liquidia Corp
($118,662,602) 19
Bridgebio Pharma, Inc.
($63,999,419) 48
Dyne Therapeutics, Inc.
($63,910,903) 17
MoonLake Immunotherapeutics
($62,962,500) 1
Sionna Therapeutics, Inc.
($55,674,636) 20
Sionna Therapeutics, Inc.
($55,674,636) 20
BeOne Medicines Ltd.
($43,467,294) 7

Most Unique Insiders Buying (>25K)

12 months
Name Unique insiders Total Trades
Eli Lilly & Co 8 8
Zenas Biopharma, Inc. 6 21
Indivior Pharmaceuticals, Inc. 6 6
CervoMed Inc. 5 12
HYPERION DEFI, INC. 5 8
Perrigo Co Plc 5 7
Summit Therapeutics Inc. 4 12
Relmada Therapeutics, Inc. 4 9
Larimar Therapeutics, Inc. 4 8
Elanco Animal Health Inc 4 6

Most Unique Insiders Selling (>25K)

12 months
Name Unique insiders Total Trades
Ani Pharmaceuticals Inc 15 54
Ionis Pharmaceuticals Inc 14 42
Liquidia Corp 12 67
Vertex Pharmaceuticals Inc / Ma 12 54
BeOne Medicines Ltd. 11 32
Uniqure N.V. 11 17
Arrowhead Pharmaceuticals, Inc. 10 22
Insmed Inc 9 42
Ptc Therapeutics, Inc. 9 40
Abeona Therapeutics Inc. 9 34

Companies with activity

1 Month 6 Month 12 Month
Name Ratio Buy $ Sell $ Ratio Buy $ Sell $ Ratio Buy $ Sell $
Ionis Pharmaceuticals Inc 0.60 $1,058,700 ($1,775,140) 0.11 $1,058,700 ($9,210,330) 0.03 $1,058,700 ($31,684,554)
MapLight Therapeutics, Inc. 0.01 $148,702 ($11,455,188) 0.03 $842,548 ($28,220,410) 0.03 $842,548 ($28,983,128)
Liquidia Corp 0.00 $0 ($30,407,838) 0.00 $0 ($161,628,490) 0.00 $0 ($185,513,344)
Dyne Therapeutics, Inc. 0.00 $0 ($24,529,261) 0.00 $274,840 ($102,882,986) 0.00 $274,840 ($103,067,398)
Sionna Therapeutics, Inc. 0.00 $0 ($7,708,563) 0.00 $0 ($95,822,256) 0.00 $0 ($156,865,204)
Viking Therapeutics, Inc. 0.00 $0 ($6,267,665) 0.02 $149,912 ($6,267,665) 0.01 $149,912 ($21,690,334)
MoonLake Immunotherapeutics 0.00 $0 ($4,318,359) 0.00 $0 ($77,039,456) 0.00 $98,808 ($83,026,619)
Immunome Inc. 0.00 $0 ($2,412,522) 0.08 $647,772 ($8,345,410) 0.13 $2,101,730 ($16,675,490)
Arcus Biosciences, Inc. 0.00 $0 ($2,031,919) 0.00 $0 ($3,174,409) 0.00 $0 ($12,591,600)
Vera Therapeutics, Inc. 0.00 $0 ($1,956,187) 0.00 $0 ($5,754,795) 0.04 $249,985 ($5,862,293)
Corcept Therapeutics Inc 0.00 $0 ($882,986) 0.42 $3,313,809 ($7,941,479) 0.16 $3,313,809 ($21,067,820)
Abeona Therapeutics Inc. 0.00 $0 ($827,935) 0.00 $0 ($2,023,465) 0.00 $0 ($3,753,653)
Entrada Therapeutics, Inc. 0.00 $0 ($807,027) 0.02 $29,316 ($1,746,254) 0.01 $29,316 ($3,595,185)
Indivior Pharmaceuticals, Inc. 0.00 $0 ($764,628) 0.01 $31,211 ($2,829,211) 0.07 $203,608 ($2,829,211)
Sagimet Biosciences Inc. 0.00 $0 ($719,429) 0.00 $0 ($824,893) 0.00 $0 ($1,114,872)
Xeris Biopharma Holdings, Inc. 0.00 $0 ($636,969) 0.00 $0 ($2,364,355) 0.00 $0 ($5,271,084)
Mirum Pharmaceuticals, Inc. 0.00 $0 ($611,273) 0.00 $0 ($1,202,252) 3.73 $8,999,984 ($2,414,931)
Precigen, Inc. 0.00 $0 ($606,000) 0.00 $0 ($18,617,046) 0.01 $235,938 ($46,482,000)
Ironwood Pharmaceuticals Inc 0.00 $0 ($578,063) 0.00 $0 ($22,314,557) 0.00 $0 ($22,508,515)
Amylyx Pharmaceuticals, Inc. 0.00 $0 ($538,868) 0.03 $51,338 ($1,743,535) 0.04 $152,183 ($4,169,323)
Puma Biotechnology, Inc. 0.00 $0 ($511,513) 0.00 $0 ($1,084,258) 0.00 $0 ($1,503,247)
Enliven Therapeutics, Inc. 0.00 $0 ($504,903) 0.00 $0 ($1,323,509) 0.00 $0 ($9,884,266)
Rapport Therapeutics, Inc. 0.00 $0 ($421,498) 0.00 $0 ($3,645,775) 0.19 $1,605,585 ($8,354,670)
Urogen Pharma Ltd. 0.00 $0 ($400,000) 0.00 $0 ($1,050,100) 0.00 $0 ($1,622,174)
BeOne Medicines Ltd. 0.00 $0 ($337,932) 0.00 $0 ($7,813,839) 0.00 $0 ($56,684,251)
Kiniksa Pharmaceuticals International, plc 0.00 $0 ($299,092) 0.00 $0 ($687,927) 0.00 $0 ($1,315,004)
Mineralys Therapeutics, Inc. 0.00 $0 ($291,441) 1.89 $8,762,797 ($4,644,544) 0.90 $53,762,774 ($59,909,964)
Olema Pharmaceuticals, Inc. 0.00 $0 ($291,162) 0.00 $0 ($291,162) 0.00 $0 ($5,482,196)
Ptc Therapeutics, Inc. 0.00 $0 ($280,743) 0.00 $0 ($8,204,870) 0.00 $0 ($12,777,219)
Ani Pharmaceuticals Inc 0.00 $0 ($272,796) 0.00 $0 ($9,899,290) 0.00 $0 ($44,554,309)
Nuvalent, Inc. 0.00 $0 ($261,363) 0.00 $0 ($261,363) 0.00 $0 ($49,326,257)
Alkermes Plc. 0.00 $0 ($208,709) 0.00 $0 ($1,026,232) 0.00 $0 ($1,255,432)
Neurogene Inc. 0.00 $0 ($173,375) 0.00 $0 ($1,133,592) 0.00 $0 ($1,133,592)
Ultragenyx Pharmaceutical Inc. 0.00 $0 ($164,372) 0.00 $0 ($3,423,217) 0.00 $0 ($4,013,412)
Bridgebio Pharma, Inc. 0.00 $0 ($160,120) 0.00 $0 ($34,217,030) 0.00 $0 ($104,203,629)
Prothena Corp Public Ltd Co 0.00 $0 ($135,975) 0.00 $0 ($135,975) 0.00 $0 ($135,975)
Korro Bio, Inc. 0.00 $0 ($130,149) 0.00 $0 ($4,417,662) 0.00 $0 ($4,417,662)
Nurix Therapeutics, Inc. 0.00 $0 ($115,989) 0.00 $0 ($1,173,364) 0.00 $0 ($1,252,296)
Aquestive Therapeutics, Inc. 0.00 $0 ($100,192) 0.00 $0 ($1,890,830) 0.00 $0 ($2,798,825)
Opus Genetics, Inc. 0.00 $0 ($86,585) 0.00 $0 ($7,863,894) 0.02 $323,693 ($16,463,894)
Pharvaris N.V. 0.00 $0 ($80,154) 0.00 $0 ($4,728,221) 0.00 $0 ($4,728,221)
Werewolf Therapeutics, Inc. 0.00 $0 ($44,749) 0.00 $0 ($1,177,507) 0.00 $0 ($3,255,559)
An2 Therapeutics, Inc. 0.00 $0 ($24,803) 0.00 $0 ($26,323) 0.00 $0 ($80,094)
Schrodinger, Inc. 0.00 $0 ($13,647) 0.00 $0 ($317,601) 0.00 $0 ($346,988)
Bicycle Therapeutics Plc 0.00 $0 ($12,957) 0.00 $0 ($130,437) 0.00 $0 ($551,656)
GENELUX CORP 0.00 $0 ($12,752) 0.00 $0 ($134,089) 0.00 $0 ($289,601)
Imunon, Inc. 0.00 $0 ($9,537) 0.00 $0 ($30,211) 0.00 $0 ($30,211)
Oric Pharmaceuticals, Inc. 0.00 $0 ($3,600) 0.00 $0 ($3,600) 0.00 $0 ($2,949,043)
RedHill Biopharma Ltd. 0.00 $0 ($1,413) 0.00 $0 ($2,987) 0.00 $0 ($2,987)
Karyopharm Therapeutics Inc. 0.00 $0 ($1,342) 0.00 $0 ($337,096) 0.00 $0 ($368,658)
Acrivon Therapeutics, Inc. 0.00 $0 ($1,008) 0.00 $0 ($1,008) 113.38 $114,341 ($1,008)
CRESCENT BIOPHARMA, INC. -- $12,375,025 $0 10.09 $12,375,025 ($1,226,126) 24.97 $30,612,625 ($1,226,126)
Parabilis Medicines, Inc. -- $6,919,551 $0 -- $7,643,080 $0 -- $7,643,080 $0
ProQR Therapeutics N.V. -- $1,111,385 $0 -- $1,342,385 $0 -- $1,342,385 $0
CytoMed Therapeutics Ltd -- $300,000 $0 -- $428,778 $0 -- $428,778 $0
Apnimed, Inc. -- $200,000 $0 -- $200,000 $0 -- $200,000 $0
Larimar Therapeutics, Inc. -- $166,890 $0 -- $25,716,890 $0 -- $25,716,890 $0
Evommune, Inc. -- $146,260 $0 0.22 $146,260 ($673,747) 0.24 $163,610 ($673,747)
Anixa Biosciences Inc -- $139,798 $0 -- $199,785 $0 -- $230,185 $0
Hcw Biologics Inc. -- $99,993 $0 -- $529,993 $0 -- $529,993 $0
Greenwich Lifesciences, Inc. -- $97,003 $0 -- $97,003 $0 -- $586,328 $0
Rani Therapeutics Holdings, Inc. -- $50,033 $0 166.18 $50,033 ($301) 4352.50 $1,310,450 ($301)
Keros Therapeutics, Inc. -- $10,610 $0 0.16 $65,500 ($421,814) 0.16 $65,500 ($421,814)
Protagenic Therapeutics, Inc.\New -- $4,806 $0 -- $4,806 $0 -- $4,806 $0
Serina Therapeutics, Inc. -- $2,030 $0 -- $76,881 $0 -- $76,881 $0
Faeth Therapeutics, Inc. -- $0 $0 -- $1,133,317 $0 -- $1,133,317 $0
Eli Lilly & Co -- $0 $0 0.00 $0 ($2,876,925) 0.84 $4,537,301 ($5,406,118)
Amicus Therapeutics, Inc. -- $0 $0 0.00 $0 ($322,839) 0.00 $0 ($1,471,085)
Arrowhead Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,554,519) 0.00 $0 ($34,306,922)
Arvinas, Inc. -- $0 $0 0.19 $268,070 ($1,418,888) 0.35 $495,080 ($1,421,163)
Apellis Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($8,153) 0.00 $0 ($12,221,660)
Aurinia Pharmaceuticals Inc. -- $0 $0 -- $25,144,033 $0 -- $27,480,033 $0
Processa Pharmaceuticals, Inc. -- $0 $0 -- $208,638 $0 -- $208,638 $0
Akebia Therapeutics, Inc. -- $0 $0 1.39 $86,588 ($62,181) 0.09 $86,588 ($962,955)
Arcutis Biotherapeutics, Inc. -- $0 $0 0.00 $0 ($2,686,490) 0.00 $0 ($11,720,809)
Zentalis Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($126,795) 0.00 $0 ($134,670)
Jazz Pharmaceuticals Plc -- $0 $0 0.00 $0 ($9,375,598) 0.00 $0 ($16,739,053)
Verastem, Inc. -- $0 $0 0.00 $0 ($109,021) 0.00 $0 ($738,403)
Regeneron Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($434,683) 0.00 $0 ($715,450)
Stoke Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,963,511) 0.00 $0 ($9,027,881)
Crinetics Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,520,753) 0.00 $0 ($2,890,190)
Travere Therapeutics, Inc. -- $0 $0 0.00 $0 ($4,124,420) 0.00 $0 ($10,026,865)
United Therapeutics Corp -- $0 $0 0.00 $0 ($1,504,287) 0.00 $0 ($2,743,588)
Insmed Inc -- $0 $0 0.00 $0 ($9,315,836) 0.00 $0 ($44,468,676)
Acadia Pharmaceuticals Inc -- $0 $0 0.00 $0 ($412,305) 0.00 $0 ($1,761,600)
Tempest Therapeutics, Inc. -- $0 $0 -- $1,000,002 $0 -- $1,000,002 $0
Q32 Bio Inc. -- $0 $0 397.79 $30,000,000 ($75,418) 138.50 $30,000,000 ($216,605)
Rallybio Corp -- $0 $0 0.00 $0 ($3,992) 0.00 $0 ($3,992)
Galectin Therapeutics Inc -- $0 $0 -- $810 $0 -- $25,546 $0
Biomarin Pharmaceutical Inc -- $0 $0 0.00 $0 ($3,154,466) 0.00 $0 ($3,154,466)
Canton Strategic Holdings, Inc. -- $0 $0 0.00 $0 ($343,882) 0.00 $0 ($343,882)
Shattuck Labs, Inc. -- $0 $0 0.61 $250,000 ($408,600) 27.40 $11,193,653 ($408,600)
Bausch Health Companies Inc. -- $0 $0 0.00 $0 ($247,836) 713.99 $333,757,793 ($467,456)
Pacira Biosciences, Inc. -- $0 $0 0.00 $0 ($457,491) 0.00 $0 ($1,386,832)
Xenon Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($133,488) 0.00 $0 ($1,280,367)
Zai Lab Ltd -- $0 $0 0.07 $65,804 ($883,325) 0.23 $354,904 ($1,559,316)
Soleno Therapeutics Inc -- $0 $0 0.00 $0 ($429,344) 0.00 $0 ($429,344)
Uniqure N.V. -- $0 $0 0.00 $0 ($2,258,860) 0.00 $0 ($2,258,860)
Vertex Pharmaceuticals Inc / Ma -- $0 $0 0.00 $0 ($53,492,348) 0.09 $5,844,183 ($65,664,392)
Mannkind Corp -- $0 $0 0.00 $0 ($65,711) 0.00 $0 ($708,687)
Syndax Pharmaceuticals Inc -- $0 $0 0.00 $0 ($780,667) 0.00 $0 ($780,667)
Viridian Therapeutics, Inc.\De -- $0 $0 -- $19,999,990 $0 423.76 $29,999,980 ($70,796)
Abbvie Inc. -- $0 $0 0.00 $0 ($5,597,068) 0.00 $0 ($8,236,287)
Nuvectis Pharma, Inc. -- $0 $0 -- $250,000 $0 -- $418,110 $0
HYPERION DEFI, INC. -- $0 $0 -- $29,580 $0 -- $641,038 $0
Rocket Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($225,234) 0.14 $68,500 ($481,417)
Lifevantage Corp -- $0 $0 2.16 $184,651 ($85,459) 0.42 $194,798 ($465,436)
Cytokinetics Inc -- $0 $0 0.00 $0 ($12,130,801) 0.00 $0 ($15,502,096)
Teva Pharmaceutical Industries Ltd -- $0 $0 0.00 $0 ($30,160,937) 0.00 $20,988 ($40,050,357)
Alnylam Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($16,804,100) 0.00 $0 ($42,288,864)
Rhythm Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($1,872,988) 0.00 $0 ($2,217,134)
Agios Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($152,255) 0.00 $0 ($467,346)
GYRE THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($82,927) 0.00 $0 ($82,927)
Zoetis Inc. -- $0 $0 -- $886,367 $0 -- $886,367 $0
Wave Life Sciences Ltd. -- $0 $0 211.76 $54,624,378 ($257,958) 16.62 $54,631,065 ($3,286,631)
Nektar Therapeutics -- $0 $0 0.00 $0 ($2,035,080) 0.00 $0 ($3,328,592)
Abbott Laboratories -- $0 $0 2.68 $1,301,477 ($485,320) 3.07 $4,402,775 ($1,435,121)
ARS Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($33,550) 0.00 $0 ($1,461,650)
Ardelyx, Inc. -- $0 $0 1.85 $1,946,331 ($1,049,240) 0.97 $1,946,331 ($2,009,444)
Bristol Myers Squibb Co -- $0 $0 0.00 $0 ($1,850,016) 0.00 $0 ($4,500,496)
Collegium Pharmaceutical, Inc -- $0 $0 0.00 $0 ($2,898,187) 0.00 $0 ($5,357,831)
Abcellera Biologics Inc. -- $0 $0 -- $241,092 $0 -- $419,552 $0
Ligand Pharmaceuticals Inc -- $0 $0 0.00 $0 ($2,797,719) 0.00 $0 ($5,365,792)
Altimmune, Inc. -- $0 $0 -- $198,439 $0 -- $325,788 $0
Vanda Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($2,824,768) 0.01 $41,500 ($2,824,768)
Theravance Biopharma, Inc. -- $0 $0 0.00 $0 ($651,804) 0.00 $0 ($2,633,575)
Elanco Animal Health Inc -- $0 $0 -- $199,781 $0 -- $1,137,688 $0
Xencor Inc -- $0 $0 0.00 $0 ($950,090) 0.00 $0 ($950,090)
Edesa Biotech, Inc. -- $0 $0 -- $233,054 $0 -- $233,054 $0
Corbus Pharmaceuticals Holdings, Inc. -- $0 $0 0.37 $101,218 ($274,502) 0.32 $101,218 ($320,614)
Roivant Sciences Ltd. -- $0 $0 0.00 $0 ($181,149,644) 0.00 $49,957 ($311,889,071)
Evolus, Inc. -- $0 $0 0.00 $0 ($79,744) 0.95 $204,486 ($214,246)
Cryoport, Inc. -- $0 $0 0.00 $0 ($6,356,126) 0.00 $0 ($6,514,666)
Organogenesis Holdings Inc. -- $0 $0 -- $40,093 $0 0.02 $40,093 ($2,619,180)
Chemomab Therapeutics Ltd. -- $0 $0 -- $20,246 $0 -- $20,246 $0
Ibio, Inc. -- $0 $0 -- $98,106 $0 -- $98,106 $0
Spyre Therapeutics, Inc. -- $0 $0 0.00 $0 ($12,767,168) 0.00 $0 ($15,504,120)
Immuneering Corp -- $0 $0 -- $35,993 $0 -- $422,978 $0
Viatris Inc -- $0 $0 0.00 $0 ($1,093,323) 0.19 $219,740 ($1,165,368)
Cingulate Inc. -- $0 $0 -- $656,964 $0 -- $656,964 $0
Johnson & Johnson -- $0 $0 0.00 $0 ($324,763) 0.01 $257,688 ($22,447,656)
Esperion Therapeutics, Inc. -- $0 $0 0.00 $0 ($342,716) 0.00 $0 ($695,474)
Oramed Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($330,744) 0.00 $0 ($330,744)
Tonix Pharmaceuticals Holding Corp. -- $0 $0 -- $418,578 $0 -- $442,639 $0
Assembly Biosciences, Inc. -- $0 $0 0.00 $0 ($14,687) 0.00 $0 ($14,687)
Royalty Pharma Plc -- $0 $0 0.00 $0 ($29,802,226) 0.00 $0 ($79,853,218)
Oruka Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,939,015) 0.00 $0 ($2,939,015)
Alzamend Neuro, Inc. -- $0 $0 -- $108,897 $0 0.56 $108,897 ($195,108)
CalciMedica, Inc. -- $0 $0 -- $199,999 $0 -- $336,118 $0
Fulcrum Therapeutics, Inc. -- $0 $0 0.00 $0 ($65,614) 0.00 $0 ($599,654)
Nuvation Bio Inc. -- $0 $0 -- $118,250 $0 -- $118,250 $0
Disc Medicine, Inc. -- $0 $0 0.00 $0 ($3,840,022) 0.00 $0 ($21,591,052)
Annexon, Inc. -- $0 $0 11.04 $3,460,219 ($313,428) 39.33 $12,327,519 ($313,428)
Lipocine Inc. -- $0 $0 -- $434,600 $0 -- $434,600 $0
Avalo Therapeutics, Inc. -- $0 $0 0.00 $0 ($565,643) 0.00 $0 ($565,643)
KYNTRA BIO, INC. -- $0 $0 -- $19,852 $0 -- $53,602 $0
Emergent Biosolutions Inc. -- $0 $0 0.00 $0 ($577,200) 0.00 $0 ($1,287,106)
Protagonist Therapeutics, Inc -- $0 $0 0.00 $0 ($184,572) 0.00 $0 ($5,241,968)
Nkarta, Inc. -- $0 $0 0.00 $0 ($4,813) 0.00 $0 ($70,422)
Ideaya Biosciences, Inc. -- $0 $0 -- $1,647,890 $0 -- $1,647,890 $0
Zomedica Corp. -- $0 $0 -- $146,903 $0 -- $275,671 $0
Phibro Animal Health Corp -- $0 $0 0.02 $317,700 ($12,717,738) 0.02 $317,700 ($20,638,034)
Anaptysbio, Inc -- $0 $0 0.00 $0 ($2,247,650) 0.00 $0 ($2,440,993)
Hepion Pharmaceuticals, Inc. -- $0 $0 -- $400,000 $0 -- $400,000 $0
Lite Strategy, Inc. -- $0 $0 -- $21,388 $0 -- $141,864 $0
Phio Pharmaceuticals Corp. -- $0 $0 -- $9,900 $0 -- $32,200 $0
Cellectar Biosciences, Inc. -- $0 $0 -- $49,997 $0 68.30 $49,997 ($732)
Prestige Consumer Healthcare Inc. -- $0 $0 0.00 $0 ($186,374) 0.00 $0 ($424,424)
Sarepta Therapeutics, Inc. -- $0 $0 0.00 $0 ($123,208) 0.00 $0 ($417,410)
Alx Oncology Holdings Inc -- $0 $0 0.00 $0 ($32,821) 131.93 $5,157,754 ($39,095)
Lexicon Pharmaceuticals, Inc. -- $0 $0 -- $722,624 $0 -- $2,722,625 $0
Amneal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($450,558) 0.00 $0 ($8,780,944)
Kura Oncology, Inc. -- $0 $0 0.00 $0 ($989,048) 0.29 $713,346 ($2,490,898)
Edgewise Therapeutics, Inc. -- $0 $0 0.00 $0 ($506,735) 0.39 $199,403 ($506,735)
Cytomx Therapeutics, Inc. -- $0 $0 0.00 $0 ($1,232,151) 0.00 $0 ($1,694,057)
Genprex, Inc. -- $0 $0 0.00 $0 ($22) 0.00 $0 ($22)
Prelude Therapeutics Inc -- $0 $0 -- $24,999,997 $0 -- $24,999,997 $0
Eton Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($3,825,717) 0.00 $0 ($4,499,431)
Supernus Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($2,034,850) 0.00 $0 ($4,640,185)
OnKure Therapeutics, Inc. -- $0 $0 0.00 $0 ($3,319) 0.00 $0 ($5,499)
Corvus Pharmaceuticals, Inc. -- $0 $0 -- $333,689 $0 -- $333,689 $0
Cocrystal Pharma, Inc. -- $0 $0 -- $67,232 $0 -- $219,806 $0
Pfizer Inc -- $0 $0 0.00 $0 ($51,400) 0.00 $0 ($51,400)
Merck & Co., Inc. -- $0 $0 0.00 $0 ($12,424,199) 0.00 $0 ($19,359,961)
Summit Therapeutics Inc. -- $0 $0 -- $103,616,650 $0 -- $126,586,111 $0
ZEVRA THERAPEUTICS, INC. -- $0 $0 0.00 $0 ($20,272) 1.58 $228,343 ($144,321)
CervoMed Inc. -- $0 $0 -- $3,000,000 $0 -- $3,737,723 $0
Ocular Therapeutix, Inc -- $0 $0 0.23 $461,354 ($2,013,826) 0.13 $461,354 ($3,456,325)
Opko Health, Inc. -- $0 $0 -- $11,350 $0 -- $4,093,941 $0
Centessa Pharmaceuticals Plc -- $0 $0 0.00 $0 ($1,927,131) 0.00 $0 ($3,395,184)
Equillium, Inc. -- $0 $0 0.00 $0 ($723,830) 0.00 $0 ($787,440)
Janux Therapeutics, Inc. -- $0 $0 0.00 $0 ($85,822) 0.00 $0 ($347,145)
Ovid Therapeutics Inc. -- $0 $0 0.00 $0 ($29,286) 0.00 $0 ($29,286)
Rezolute, Inc. -- $0 $0 -- $28,500 $0 -- $284,397 $0
Climb Bio, Inc. -- $0 $0 0.00 $0 ($879,382) 0.89 $779,626 ($879,382)
Organon & Co. -- $0 $0 0.00 $0 ($353,076) 1.42 $501,755 ($353,076)
Annovis Bio, Inc. -- $0 $0 -- $1,641,759 $0 -- $4,456,876 $0
PALVELLA THERAPEUTICS, INC. -- $0 $0 -- $849,974 $0 -- $849,974 $0
Tyra Biosciences, Inc. -- $0 $0 0.00 $0 ($262,965) 0.00 $0 ($10,061,326)
CYPHERPUNK TECHNOLOGIES INC. -- $0 $0 0.00 $0 ($42,630) 0.00 $0 ($5,112,091)
Xilio Therapeutics, Inc. -- $0 $0 -- $43,950 $0 -- $43,950 $0
Axsome Therapeutics, Inc. -- $0 $0 0.00 $0 ($8,188,876) 0.01 $200,466 ($21,562,719)
Cns Pharmaceuticals, Inc. -- $0 $0 -- $34,002 $0 -- $34,002 $0
Dermata Therapeutics, Inc. -- $0 $0 97.01 $1,270 ($13) 97.01 $1,270 ($13)
Atea Pharmaceuticals, Inc. -- $0 $0 -- $25,446 $0 -- $25,446 $0
Spero Therapeutics, Inc. -- $0 $0 0.00 $0 ($314,855) 0.00 $0 ($568,328)
Madrigal Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($6,506,959) 3.57 $61,921,024 ($17,348,067)
Aldeyra Therapeutics, Inc. -- $0 $0 -- $523,550 $0 4.72 $536,800 ($113,713)
Oncotelic Therapeutics, Inc. -- $0 $0 -- $37,832 $0 -- $37,832 $0
Natures Sunshine Products Inc -- $0 $0 0.00 $0 ($1,693,617) 0.00 $0 ($2,504,407)
Rein Therapeutics, Inc. -- $0 $0 -- $74,561 $0 -- $74,561 $0
TALPHERA, INC. -- $0 $0 -- $304,001 $0 -- $304,001 $0
Lantern Pharma Inc. -- $0 $0 -- $200,001 $0 -- $200,001 $0
Milestone Pharmaceuticals Inc. -- $0 $0 0.00 $0 ($82,490) 0.00 $0 ($180,365)
Tango Therapeutics, Inc. -- $0 $0 0.00 $0 ($997,973) 0.00 $0 ($1,725,098)
Maravai Lifesciences Holdings, Inc. -- $0 $0 0.00 $0 ($254,000) 7.40 $1,880,244 ($254,000)
Renovorx, Inc. -- $0 $0 -- $19,690 $0 -- $93,723 $0
Terns Pharmaceuticals, Inc. -- $0 $0 0.00 $0 ($49,693) 0.00 $0 ($101,652)
Rigel Pharmaceuticals Inc -- $0 $0 0.00 $0 ($160,425) 0.00 $0 ($160,425)
Promis Neurosciences Inc. -- $0 $0 -- $211,545 $0 -- $211,545 $0
HARROW, INC. -- $0 $0 -- $468,720 $0 -- $468,720 $0
Whitehawk Therapeutics, Inc. -- $0 $0 0.00 $0 ($2,459,560) 0.00 $0 ($2,459,560)
Lyell Immunopharma, Inc. -- $0 $0 0.00 $0 ($304,858) 0.00 $0 ($526,843)
Pepgen Inc. -- $0 $0 0.00 $0 ($59,312) 505.80 $30,000,000 ($59,312)
Maia Biotechnology, Inc. -- $0 $0 -- $203,776 $0 -- $658,566 $0
ASTRAZENECA PLC -- $0 $0 0.00 $0 ($2,209,482) 0.00 $0 ($2,209,482)
Legend Biotech Corp -- $0 $0 0.00 $0 ($258,204) 0.00 $0 ($258,204)
Ascendis Pharma A/S -- $0 $0 0.06 $284,412 ($4,641,021) 0.06 $284,412 ($4,641,021)
BELITE BIO, INC -- $0 $0 0.00 $0 ($8,524,794) 0.00 $0 ($8,524,794)
NovaBridge Biosciences -- $0 $0 13.56 $577,300 ($42,584) 13.56 $577,300 ($42,584)
AC Immune SA -- $0 $0 0.00 $0 ($59,360) 0.00 $0 ($59,360)
ONCOLYTICS BIOTECH INC -- $0 $0 -- $258,845 $0 -- $362,615 $0
Connect Biopharma Holdings Ltd -- $0 $0 -- $4,373,610 $0 -- $4,373,610 $0
NeuroSense Therapeutics Ltd. -- $0 $0 -- $400,000 $0 -- $400,000 $0
Valion Bio, Inc. -- $0 $0 -- $28,408 $0 -- $28,408 $0
NewcelX Ltd. -- $0 $0 -- $374,998 $0 -- $374,998 $0
SciSparc Ltd. -- $0 $0 0.00 $0 ($4,620) 0.00 $0 ($4,620)
NewAmsterdam Pharma Co N.V. -- $0 $0 0.00 $0 ($2,963,227) 0.01 $58,420 ($6,551,572)
Cadrenal Therapeutics, Inc. -- $0 $0 0.00 $0 ($388,290) 0.00 $0 ($1,098,101)
60 DEGREES PHARMACEUTICALS, INC. -- $0 $0 -- $10,131 $0 -- $30,095 $0
Adlai Nortye Ltd. -- $0 $0 0.00 $0 ($132) 0.00 $0 ($132)
FibroBiologics, Inc. -- $0 $0 -- $72,960 $0 -- $120,560 $0
NEONC TECHNOLOGIES HOLDINGS, INC. -- $0 $0 -- $423,560 $0 -- $615,579 $0
Contineum Therapeutics, Inc. -- $0 $0 0.00 $0 ($228,155) 0.00 $0 ($385,013)
IMPACT BIOMEDICAL INC. -- $0 $0 0.00 $0 ($57,835) 0.00 $0 ($57,835)
Zenas Biopharma, Inc. -- $0 $0 -- $8,755,746 $0 -- $26,646,644 $0
Mbx Biosciences, Inc. -- $0 $0 21.24 $525,663 ($24,755) 527.72 $13,063,425 ($24,755)
Bicara Therapeutics Inc. -- $0 $0 -- $4,800,000 $0 66.68 $4,800,000 ($71,981)
Upstream Bio, Inc. -- $0 $0 0.00 $0 ($77,193) 0.00 $0 ($77,193)
Telix Pharmaceuticals Ltd -- $0 $0 -- $996,738 $0 -- $996,738 $0
Nasus Pharma Ltd -- $0 $0 -- $61,809 $0 -- $61,809 $0
Veradermics, Inc -- $0 $0 -- $9,764,124 $0 -- $15,542,467 $0
Polaryx Therapeutics, Inc. -- $0 $0 -- $367,994 $0 -- $367,994 $0
Generate Biomedicines, Inc. -- $0 $0 -- $300,800 $0 -- $300,800 $0
Seaport Therapeutics, Inc. -- $0 $0 -- $235,768 $0 -- $235,768 $0
Kardigan, Inc. -- $0 $0 -- $40,000,000 $0 -- $40,000,000 $0
Amphastar Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($149,235)
KALA BIO, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($248,725)
Harmony Biosciences Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,799,327)
Arcturus Therapeutics Holdings Inc. -- $0 $0 -- $0 $0 -- $20,499 $0
Cartesian Therapeutics, Inc. -- $0 $0 -- $0 $0 0.80 $205,797 ($258,671)
Cumberland Pharmaceuticals Inc -- $0 $0 -- $0 $0 -- $5,892 $0
Tg Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($835,118)
Akero Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,563,296)
Hookipa Pharma Inc. -- $0 $0 -- $0 $0 0.00 $0 ($20,684)
Enanta Pharmaceuticals Inc -- $0 $0 -- $0 $0 0.00 $0 ($183,167)
Biomea Fusion, Inc. -- $0 $0 -- $0 $0 -- $196,731 $0
Bolt Biotherapeutics, Inc. -- $0 $0 -- $0 $0 -- $1,152 $0
Clene Inc. -- $0 $0 -- $0 $0 -- $216,664 $0
Phathom Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($12,653)
Aprea Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $60,907 $0
Dynavax Technologies Corp -- $0 $0 -- $0 $0 -- $41,116 $0
Perrigo Co Plc -- $0 $0 -- $0 $0 -- $562,500 $0
Decoy Therapeutics Inc. -- $0 $0 -- $0 $0 1142.93 $19,740 ($17)
Iterum Therapeutics Plc -- $0 $0 -- $0 $0 -- $13,045 $0
Gossamer Bio, Inc. -- $0 $0 -- $0 $0 -- $50,016 $0
Applied Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,816)
XOMA Royalty Corp -- $0 $0 -- $0 $0 -- $2,505,000 $0
Oragenics Inc -- $0 $0 -- $0 $0 0.00 $0 ($198)
Relmada Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $2,536,155 $0
Synlogic, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($284)
Assertio Holdings, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($6,806)
Bespoke Extracts, Inc. -- $0 $0 -- $0 $0 -- $1,760 $0
Heron Therapeutics, Inc. /De/ -- $0 $0 -- $0 $0 -- $2,649,819 $0
Cue Biopharma, Inc. -- $0 $0 -- $0 $0 -- $99,747 $0
Monopar Therapeutics -- $0 $0 -- $0 $0 0.31 $104,925 ($343,889)
Galera Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($1,407)
Savara Inc -- $0 $0 -- $0 $0 0.00 $0 ($121,220)
Macrogenics Inc -- $0 $0 -- $0 $0 -- $150,515 $0
Mustang Bio, Inc. -- $0 $0 -- $0 $0 0.98 $238 ($241)
Avidity Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5,556,206)
Pliant Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($163,620)
Design Therapeutics, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($2,953,792)
Cogent Biosciences, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($139,578,705)
Therapeuticsmd, Inc. -- $0 $0 -- $0 $0 -- $14,031 $0
Silo Pharma, Inc. -- $0 $0 -- $0 $0 -- $7,657 $0
Soligenix, Inc. -- $0 $0 -- $0 $0 -- $20,000 $0
Cormedix Inc. -- $0 $0 -- $0 $0 0.31 $275,500 ($886,600)
Aditxt, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($5)
Verrica Pharmaceuticals Inc. -- $0 $0 -- $0 $0 -- $17,972,698 $0
Palatin Technologies Inc -- $0 $0 -- $0 $0 0.00 $0 ($9,461)
Catalyst Pharmaceuticals, Inc. -- $0 $0 -- $0 $0 -0.00 $0 $908,000
Sellas Life Sciences Group, Inc. -- $0 $0 -- $0 $0 -- $100,806 $0
Immix Biopharma, Inc. -- $0 $0 -- $0 $0 -- $15,148 $0
Rockwell Medical, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($23,677)
Tenax Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $204,468 $0
Skye Bioscience, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($800,548)
FILANA THERAPEUTICS, INC. -- $0 $0 -- $0 $0 -- $1,231,784 $0
Geovax Labs, Inc. -- $0 $0 -- $0 $0 -- $6,240 $0
Perspective Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $42,241 $0
Aptevo Therapeutics Inc. -- $0 $0 -- $0 $0 -- $20,134 $0
Benitec Biopharma Inc. -- $0 $0 -- $0 $0 -- $22,442,099 $0
Pasithea Therapeutics Corp. -- $0 $0 -- $0 $0 -- $149,999 $0
Biohaven Ltd. -- $0 $0 -- $0 $0 -- $33,144,763 $0
Carisma Therapeutics Inc. -- $0 $0 -- $0 $0 0.00 $0 ($124,343)
BIOXYTRAN, INC -- $0 $0 -- $0 $0 -- $126,000 $0
ELITE PHARMACEUTICALS INC /NV/ -- $0 $0 -- $0 $0 0.00 $0 ($499,200)
Akari Therapeutics Plc -- $0 $0 -- $0 $0 -- $19,540 $0
Quoin Pharmaceuticals, Ltd. -- $0 $0 -- $0 $0 -- $128,640 $0
Ctt Pharmaceutical Holdings, Inc. -- $0 $0 -- $0 $0 -- $11,801 $0
Mural Oncology plc -- $0 $0 -- $0 $0 0.00 $0 ($25,414)
ALUMIS INC. -- $0 $0 -- $0 $0 -- $29,697,125 $0
ACTUATE THERAPEUTICS, INC. -- $0 $0 -- $0 $0 0.00 $0 ($1,624,000)
Bioage Labs, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($4,223,036)
Camp4 Therapeutics Corp -- $0 $0 -- $0 $0 -- $2,054,995 $0
Septerna, Inc. -- $0 $0 -- $0 $0 0.00 $0 ($63,223)
Aardvark Therapeutics, Inc. -- $0 $0 -- $0 $0 -- $450,312 $0
Turn Therapeutics Inc. -- $0 $0 -- $0 $0 -- $242,745 $0
Ataibeckley Inc. -- $0 $0 -- $0 $0 0.00 $0 ($154,377)