Insider Buying and Selling - SPRO

Transaction	Filed	Name	Type	Shares @ Price	Value	Balance change		Ownership
02/06/2026	02/09/2026	Keutzer Timothy Chief Operating Officer Officer	Sell	-18,652 @ $2.36	($44,018.72)	742,506	(-2.45%)	Direct
02/06/2026	02/09/2026	Rajavelu Esther Chief Executive Officer, Chief Financial Officer a CEO	Sell	-87,917 @ $2.36	($207,484.12)	1,012,091	(-7.99%)	Direct
02/04/2026	02/05/2026	Keutzer Timothy Chief Operating Officer Officer	Sell	-3,471 @ $2.24	($7,775.04)	761,158	(-0.45%)	Direct
02/03/2026	02/05/2026	Keutzer Timothy Chief Operating Officer Officer	Sell	-24,224 @ $2.14	($51,839.36)	764,629	(-3.07%)	Direct
02/02/2026	02/05/2026	Keutzer Timothy Chief Operating Officer Officer	Sell	-18,891 @ $2.20	($41,560.20)	788,853	(-2.34%)	Direct
02/02/2026	02/04/2026	Rajavelu Esther Chief Executive Officer, Chief Financial Officer a CEO	Sell	-18,442 @ $2.20	($40,572.40)	1,100,008	(-1.65%)	Direct
11/07/2025	11/12/2025	Rajavelu Esther Chief Executive Officer, Chief Financial Officer a CEO	Sell	-40,270 @ $2.37	($95,439.90)	869,450	(-4.43%)	Direct
08/28/2025	09/03/2025	Keutzer Timothy Chief Operating Officer Officer	Sell	-1,695 @ $1.97	($3,339.15)	739,744	(-0.23%)	Direct
08/28/2025	09/03/2025	Mahadevia Ankit Director	Sell	-6,572 @ $1.97	($12,946.84)	703,294	(-0.93%)	Direct

Spero Therapeutics, Inc. - SPRO